Association of <Emphasis Type="Italic">ADAM10</Emphasis> and <Emphasis Type="Italic">CAMK2A</Emphasis> Polymorphisms with Conduct Disorder: Evidence from Family-Based Studies

Twin and family studies have shown that genetic factors play a role in the development of conduct disorder (CD). The purpose of this study was to identify genetic variants associated with CD using a family-based association study. We used 4,720 single nucleotide polymorphisms (SNPs) from the Illumina Panel and 11,120 SNPs from the Affymetrix 10K GeneChips genotyped in 155 Caucasian nuclear families from Genetic Analysis Workshop (GAW) 14, a subset from the Collaborative Study on the Genetics of Alcoholism (COGA). 20 SNPs had suggestive associations with CD (p < 10⁻³), nine of which were located in known genes, including ADAM10 (rs383902, p = 0.00036) and CAMK2A (rs2053053, p = 0.00098). Our results were verified using the International Multi-Center ADHD Genetics Project (IMAGE) dataset. In conclusion, we identified several loci associated with CD. Especially, the two genes (ADAM10 and CAMK2A) have been reported to be associated with Alzheimer’s disease, bipolar disorder and depression. These findings may serve as a resource for replication in other populations.     

Predictors of Depressive Symptoms Among Children Affected by HIV in Rural China: A 3-Year Longitudinal Study

The current study was designed to examine the trend of depression among children affected by HIV (n = 1,221) in rural China over a period of 3 years and to explore baseline psychosocial factors that can predict depressive symptoms at 1- and 2-year follow-ups. Baseline depression score, trusting relationship with caregivers, perceived public stigma against children affected by HIV, and future expectation at baseline positively predicted the 1-year follow-up depression, while children’ self-report health status, self-esteem, and perceived social support negatively predicted depression at 1-year follow-up survey. Depression and self-report health status at baseline significantly predicted depression at the 2-year follow-up. The data in the current study suggested that depressive symptoms were chronic or recurring among some children affected by HIV/AIDS. The findings also underscore the importance of early identification, early intervention, and ongoing counseling for mental health problems among children affected by HIV/AIDS. Future psychological support programs need to target both mental health symptoms and resilient factors that will help these children to cope with adverse life events associated with HIV/AIDS.     

Saving Lives: For the Best Outcome?

Philosophia - In this article, I critique a moral argument developed in Frances Kamm’s Intricate Ethics: Rights, Responsibilities, and Permissible Harm. The argument, which I label the Best...     

Sex differences of parental phubbing on online hostility among adolescents: A moderated mediation model

To explore the relationship between parental phubbing (PP) and adolescent online hostility and its' psychological mechanism, 689 Chinese adolescents were recruited to complete a paper-and-pencil questionnaire. We took cyber flaming (CF) as an overall category for hostile online communication to investigate the relationship between PP and CF and the mediating role of perspective-taking (PT) in this relationship and examined whether there is a sex difference in this process. After controlling the average daily online time, the results showed that PP predicted adolescent CF positively. The relationship between PP and CF was partially mediated by PT. The effect of PP on PT was moderated by sex, with the result being significant only for boys. Related findings and future directions were discussed.     

歧视知觉与心理健康的关系:基于中国留守儿童的元分析

研究以心理健康双因素模型为视角,运用元分析技术梳理了留守儿童歧视知觉与积极和消极心理健康的关系,并探究了影响其关系的调节变量。通过文献检索与筛选,共27篇中英文文献,56个独立样本纳入元分析,包含被试17146名。结果显示,歧视知觉与积极心理健康指标呈显著的负相关关系(r=-0.298),与消极心理健康指标呈显著的正相关关系(r=0.365)。调节效应分析发现,留守儿童歧视知觉与积极心理健康的关系受到歧视知觉测量工具的影响,与消极心理健康的关系受到歧视知觉测量工具、学龄段以及消极结果类型的影响。同时,元回归分析发现,文献年份对歧视知觉与积极心理健康指标关系的调节效应显著; 性别对歧视知觉与积极和消极心理健康关系的调节作用均不显著。研究结果进一步明确了留守儿童歧视知觉与积极和消极心理健康的关系,为探索提升留守儿童心理社会适应的新路径提供了借鉴。     

When the “Charm of Three” Fades: Mental Imagery Moderates the Impact of the Number of Ad Claims on Persuasion

Given the prevalence of imagery appeals in today’s marketplace, the current research studies the role of mental imagery in how consumers process and react to advertisements with different numbers of ad claims. Past research has proposed “three” as the magical number of ad claims that maximizes persuasion, with more than three ad claims increasing skepticism and reducing evaluation. In the current research, we replicate this so-called “charm of three” effect, but only when consumers do not engage in mental imagery; when they do, however, we find that the effect is moderated, in that more ad claims beyond three produces more favorable product evaluation. Additionally, we provide evidence that the moderating effect of mental imagery is driven by transportation and skepticism toward the ad claims, with mental imagery increasing transportation and decreasing skepticism when there are more than three ad claims. Our research contributes to a better understanding of the “charm of three” effect, its boundary conditions, and underlying mechanism.     

心理学对经济学的涉入——从理性自利到社会偏好的决策框架

理性认知能力与社会偏好存在紧密的关联。文章简要回顾了经济决策理论从理性模型到有限理性模型和社会偏好模型的发展进程,论述了人们理性的局限性及其根源,并进一步探讨理性认知能力与社会偏好的关系。对人类以及灵长目动物的研究显示,有限理性可能是由根源于演化的适应性机制所导致。人类不公平厌恶的起源、个体公平能力的发展规律和表征公平的大脑结构上的证据表明,理性认知能力能让人更好地抑制自私性,实现更高层次的公平。     

城镇化进程中离乡农民心理健康特点调查及心理素质、相对剥夺感的影响机制

为探讨城镇化进程中离乡农民的心理健康特点以及心理素质、相对剥夺感对其的影响,通过量表对1339名城乡居民进行调查。结果发现:离乡与留乡农民在幸福感、拥有生命意义感、感知控制感、心理素质方面显著低于城镇居民,在状态焦虑方面显著高于城镇居民; 离乡农民在抑郁上显著高于城镇居民,在感知控制感上显著高于留乡农民,在心理素质上显著低于留乡农民; 留乡农民在相对剥夺感上显著高于城镇居民; 离乡农民的幸福感、拥有生命意义感、感知控制感态与相对剥夺感呈显著负相关,与心理素质呈显著正相关; 离乡农民的抑郁、状态焦虑与相对剥夺感呈显著正相关,与心理素质呈显著负相关; 离乡农民的相对剥夺感与心理素质之间呈显著负相关。心理素质除了可以直接预测心理健康各项指标,还可以通过相对剥夺感的中介作用,间接预测幸福感、抑郁及状态焦虑。提升心理素质和降低相对剥夺感是离乡农民心理健康服务的重要切入点。     

Effects of a Multilevel Resilience-Based Intervention on Mental Health for Children Affected by Parental HIV: A Cluster Randomized Controlled Trial

Journal of Child and Family Studies - The present study aimed to examine the efficacy of the Child-Caregiver-Advocacy Resilience (ChildCARE) intervention, a multilevel resilience-based psychosocial...     

Regulatory Focus as a Mediator between Perceived Parenting Style and Friendship Intimacy in Chinese Emerging Adulthood

Journal of Child and Family Studies - In this study, we examined the relationship continuity between parent–child relationships and friendships. Based on the theoretical framework of the...