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281.
Previous work has shown that preterm infants are at higher risk for cognitive/language delays than full‐term infants. Recent studies, focusing on prosody (i.e. rhythm, intonation), have suggested that prosodic perception development in preterms is indexed by maturational rather than postnatal/listening age. However, because prosody is heard in‐utero, and preterms thus lose significant amounts of prenatal prosodic experience, both their maturation level and their prosodic experience (listening age) are shorter than that of full‐terms for the same postnatal age. This confound does not apply to the acquisition of phonetics/phonotactics (i.e. identity and order of consonants/vowels), given that consonant differences in particular are only perceived after birth, which could lead to a different developmental pattern. Accordingly, we explore the possibility that consonant‐based phonotactic perception develops according to listening age. Healthy French‐learning full‐term and preterm infants were tested on the perception of consonant sequences in a behavioral paradigm. The pattern of development for full‐term infants revealed that 7‐month‐olds look equally at labial‐coronal (i.e. /pat/) compared to coronal‐labial sequences (i.e. /tap/), but that 10‐month‐olds prefer the labial‐coronal sequences that are more frequent in the French lexicon. Preterm 10‐month‐olds (having 10 months of phonetic listening experience but 7 months of maturational age) behaved as full‐term 10‐month‐olds. These results establish that preterm developmental timing for consonant‐based phonotactic acquisition is based on listening age (experience with input). This questions the interpretation of previous results on prosodic acquisition in terms of maturational constraints, and raises the possibility that different constraints apply to the acquisition of different phonological subcomponents.  相似文献   
282.
The ability of an aphasic subject with agrammatism in both comprehension and production to transcribe quantities from Roman numerals to Arabic and the reverse was investigated. Systematic errors in the transcoding processes were observed that could not be accounted for by the peculiarities of the two ideographic coding systems or by difficulties with direct transcoding rules. The results are discussed in the framework of the current debate on preserved/impaired hierarchical syntactical knowledge of agrammatic subjects. The findings paralleled the results of previous studies on the transcoding skills of agrammatics from/to alphabetic numerals to/from digital forms. In the case of this particular patient, it is therefore tentatively concluded in favor of preserved syntactical knowledge.  相似文献   
283.
The effect of visual distracting stimuli upon the straight alleyway performance of dorsal hippocampectomized Wistar rats was investigated. In comparison with control animals it was observed that dorsal hippocampectomized animals (1) ambulated more during the preexposure phase, (2) acquired at the same rate a running response for food (training phase), (3) reacted similarly to a new visual stimulus (black cards) presented in a sector of the alleyway, and (4) habituated to successive presentations of that stimulus in the same place. (5) However, dorsal hippocampectomized rats did not react, unlike the controls, to the presentation of the same stimulus in another place of the alleyway but (6) reacted to the visual pattern change of the stimulus (now black/white check cards) in the same place. These results indicate that under certain experimental conditions, hippocampus-lesioned animals are capable of interrupting a running response for food in order to explore a new conspicuously located stimulus, habituate to repeated presentations of that stimulus, and to react to a new pattern of visual stimulation. They suggest that hippocampectomized rats do not lose the capacity to react to a new stimulus; the disruption seems to be related to the spatial context of stimulus presentation, supporting a spatial mapping hypothesis of hippocampal function.  相似文献   
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The abilities of aphasic patients to perform a sentence-picture matching task were investigated on simple declarative reversible sentences. Two factors were found to differentially affect Broca's versus Wernicke's aphasics' performance: sentence plausibility and spatial arrangement. Sentence plausibility, that is to say, the liability of two given nouns in a sentence to act as agent and recipient according to normal subjects' expectancies, had a significant effect on the frequency of correct responses of Broca's aphasics but not on those of Wernicke's. Conversely, the latter were found to be more sensitive to a match or mismatch in the left-to-right spatial arrangement of the grammatical subject and object in a sentence on the one hand, and the order of the corresponding personages in the picture on the other. The results are discussed in terms of “frame selection” and the handling of ordered structure strategies contributing to normal system, but selectively disturbed in the case of brain damage.  相似文献   
286.
The present study investigated the comprehension of aphasic subjects as to locative prepositions “in,” “on,” and “under.” Patients had to locate a movable object with reference to a stationary referential object in order to achieve the spatial relations requested under oral instructions. The influence of two types of contextual relations between the objects in each stimulus pair on the subjects' performances was examined. Spatial relations were biased by the conventional knowledge of the most normal relationship between the two elements in everyday life in Experiment 1; in Experiment 2, perceptivomotor constraints constituted the contextual bias. Analyzing the patients' responses in the light of developmental strategies did not lend support to the regression hypothesis. Broca's aphasics were sensitive to the two contextual factors investigated; Wernickes' performances were affected only by the perceptivomotor contextual bias. The results are discussed with reference to earlier studies on the differential syntactical comprehension skills of Broca's and Wernicke's aphasics in sentence-picture matching tasks and production tasks.  相似文献   
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With the high-amplitude sucking procedure, newborns were presented with two lists of phonetically varied Japanese words differing in pitch contour. Discrimination of the lists was found, thus indicating that newborns are able to extract pitch contour information at the word level.  相似文献   
290.
Affective deficits have long been considered a prominent feature of schizophrenia and play a central role in recent theory and research on the pathophysiology of this disorder. However, it has recently been argued that current approaches to the conceptualization and assessment of affective flattening in schizophrenia are confounded by the social and neuromotor deficits that are also prevalent in this disorder. Insensitivity to pain in individuals with schizophrenia — a phenomenon that has been reported frequently but never systematically investigated — provides one approach to examining affective flattening unconfounded by social and neuromotor deficits. Two studies are described in which signal detection theory measures of thermal pain sensitivity were examined in patients with schizophrenia, mood disorder, and normal controls; in addition, in the patients with schizophrenia, the relationships between these measures and measures of affective deficits were examined. Patients with schizophrenia had significantly poorer sensory discrimination of painful thermal stimuli than control subjects, but did not differ from controls with respect to their response criterion for reports of pain; patients with mood disorder had a significantly higher (i.e., more stoical) criterion for reports of pain than controls. As predicted, among the patients with schizophrenia, higher response criterion was significantly correlated with greater affective flattening and less intense affective experience (as well as with fewer positive symptoms and poorer premorbid adjustment). The results of these studies suggest that pain insensitivity in schizophrenia may reflect affective as well as sensory abnormalities, and that pain insensitivity in schizophrenia may provide a method for studying affective flattening in this disorder that is relatively independent of the social and neuromotor deficits that confound existing measures of this symptom. Continued examination of the relationship between pain insensitivity and affective deficits in schizophrenia is also important because numerous clinical reports have suggested that pain insensitivity is detrimental to health and can have life-threatening consequences in individuals with this disorder.This research was supported, in part, by research grants from the National Institute of Neurological Disorders and Stroke to Robert H. Dworkin (NS-30714) and W. Crawford Clark (NS-09263, NS-20248).  相似文献   
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