Syntactical knowledge in a case of agrammatism: Evidence from transcoding Roman and Arabic numerals

The ability of an aphasic subject with agrammatism in both comprehension and production to transcribe quantities from Roman numerals to Arabic and the reverse was investigated. Systematic errors in the transcoding processes were observed that could not be accounted for by the peculiarities of the two ideographic coding systems or by difficulties with direct transcoding rules. The results are discussed in the framework of the current debate on preserved/impaired hierarchical syntactical knowledge of agrammatic subjects. The findings paralleled the results of previous studies on the transcoding skills of agrammatics from/to alphabetic numerals to/from digital forms. In the case of this particular patient, it is therefore tentatively concluded in favor of preserved syntactical knowledge.     

Sentence understanding and knowledge of the world: Evidences from a sentence-picture matching task performed by aphasic patients

The abilities of aphasic patients to perform a sentence-picture matching task were investigated on simple declarative reversible sentences. Two factors were found to differentially affect Broca's versus Wernicke's aphasics' performance: sentence plausibility and spatial arrangement. Sentence plausibility, that is to say, the liability of two given nouns in a sentence to act as agent and recipient according to normal subjects' expectancies, had a significant effect on the frequency of correct responses of Broca's aphasics but not on those of Wernicke's. Conversely, the latter were found to be more sensitive to a match or mismatch in the left-to-right spatial arrangement of the grammatical subject and object in a sentence on the one hand, and the order of the corresponding personages in the picture on the other. The results are discussed in terms of “frame selection” and the handling of ordered structure strategies contributing to normal system, but selectively disturbed in the case of brain damage.     

Processing of locatives “in,” “on,” and “under” by aphasic patients: An analysis of the regression hypothesis

The present study investigated the comprehension of aphasic subjects as to locative prepositions “in,” “on,” and “under.” Patients had to locate a movable object with reference to a stationary referential object in order to achieve the spatial relations requested under oral instructions. The influence of two types of contextual relations between the objects in each stimulus pair on the subjects' performances was examined. Spatial relations were biased by the conventional knowledge of the most normal relationship between the two elements in everyday life in Experiment 1; in Experiment 2, perceptivomotor constraints constituted the contextual bias. Analyzing the patients' responses in the light of developmental strategies did not lend support to the regression hypothesis. Broca's aphasics were sensitive to the two contextual factors investigated; Wernickes' performances were affected only by the perceptivomotor contextual bias. The results are discussed with reference to earlier studies on the differential syntactical comprehension skills of Broca's and Wernicke's aphasics in sentence-picture matching tasks and production tasks.     

Affective deficits and pain insensitivity in schizophrenia

Affective deficits have long been considered a prominent feature of schizophrenia and play a central role in recent theory and research on the pathophysiology of this disorder. However, it has recently been argued that current approaches to the conceptualization and assessment of affective flattening in schizophrenia are confounded by the social and neuromotor deficits that are also prevalent in this disorder. Insensitivity to pain in individuals with schizophrenia — a phenomenon that has been reported frequently but never systematically investigated — provides one approach to examining affective flattening unconfounded by social and neuromotor deficits. Two studies are described in which signal detection theory measures of thermal pain sensitivity were examined in patients with schizophrenia, mood disorder, and normal controls; in addition, in the patients with schizophrenia, the relationships between these measures and measures of affective deficits were examined. Patients with schizophrenia had significantly poorer sensory discrimination of painful thermal stimuli than control subjects, but did not differ from controls with respect to their response criterion for reports of pain; patients with mood disorder had a significantly higher (i.e., more stoical) criterion for reports of pain than controls. As predicted, among the patients with schizophrenia, higher response criterion was significantly correlated with greater affective flattening and less intense affective experience (as well as with fewer positive symptoms and poorer premorbid adjustment). The results of these studies suggest that pain insensitivity in schizophrenia may reflect affective as well as sensory abnormalities, and that pain insensitivity in schizophrenia may provide a method for studying affective flattening in this disorder that is relatively independent of the social and neuromotor deficits that confound existing measures of this symptom. Continued examination of the relationship between pain insensitivity and affective deficits in schizophrenia is also important because numerous clinical reports have suggested that pain insensitivity is detrimental to health and can have life-threatening consequences in individuals with this disorder.This research was supported, in part, by research grants from the National Institute of Neurological Disorders and Stroke to Robert H. Dworkin (NS-30714) and W. Crawford Clark (NS-09263, NS-20248).     

Rats with dorsal hippocampal lesions do react to new stimuli but not to spatial changes of known stimuli

The effect of visual distracting stimuli upon the straight alleyway performance of dorsal hippocampectomized Wistar rats was investigated. In comparison with control animals it was observed that dorsal hippocampectomized animals (1) ambulated more during the preexposure phase, (2) acquired at the same rate a running response for food (training phase), (3) reacted similarly to a new visual stimulus (black cards) presented in a sector of the alleyway, and (4) habituated to successive presentations of that stimulus in the same place. (5) However, dorsal hippocampectomized rats did not react, unlike the controls, to the presentation of the same stimulus in another place of the alleyway but (6) reacted to the visual pattern change of the stimulus (now black/white check cards) in the same place. These results indicate that under certain experimental conditions, hippocampus-lesioned animals are capable of interrupting a running response for food in order to explore a new conspicuously located stimulus, habituate to repeated presentations of that stimulus, and to react to a new pattern of visual stimulation. They suggest that hippocampectomized rats do not lose the capacity to react to a new stimulus; the disruption seems to be related to the spatial context of stimulus presentation, supporting a spatial mapping hypothesis of hippocampal function.     

Predictors of picture naming speed.

We report the results of a large-scale picture naming experiment in which we evaluated the potential contribution of nine theoretically relevant factors to naming latencies. The experiment included a large number of items and a large sample of participants. In order to make this experiment as similar as possible to classic picture naming experiments, participants were familiarized with the materials during a training session. Speeded naming latencies were determined by a software key on the basis of the digital recording of the responses. The effects of various variables on these latencies were assessed with multiple regression techniques, using a repeated measures design. The interpretation of the observed effects is discussed in relation to previous studies and current views on lexical access during speech production.     

Discrediting Identity Work: Understandings of Intimate Partner Violence by Transgender Survivors

This study explores how individuals can actively work to discredit identity work. We examine eighteen transgender victims’ accounts of intimate partner violence (IPV), providing insight into how abusers undermine victims’ constructions of self-concepts. Our findings illustrate two primary strategies of discrediting identity work: altercasting and targeting sign-vehicles, including controlling through props. Empirically examining the accounts of transgender IPV victims’ experiences contributes to addressing a serious gap in research on transgender IPV victims, while expanding theoretical understandings of processes of discrediting identity work within the context of abusive intimate relationships.     

Human biological and nonbiological point-light movements: Creation and validation of the dataset

Human action perception is so powerful that people can identify movement efficiently in the absence of pictorial information, such as in point-light displays. Interest is growing in this type of stimulus for research in neuroscience. This interest stems from the advantage of separating the component of pure human action kinematics from other pictorial information, such as facial expression and muscle contraction. Although several groups have previously developed datasets of human point-light actions, due to the lack of datasets composed of daily actions with short durations, we developed 20 biological and 40 control (scrambled) point-light movements by using the technique of recording people wearing reflector patches. The videos are about 1 s long. Subsequently, we performed a judgment task in which 100 participants (50 male and 50 female) evaluated each video according to three categories: human action resemblance, performed action, and gender of actor. We present the mean scores of each evaluation for each video, and further propose a selection of the most suitable videos to be used as human point-light action displays and scrambled point-light displays for control. Finally, we discuss our findings on the gender attributions of the point-light displays.