The objective of this study investigated cognitive impairments and their correlations with fractional anisotropy (FA) and mean diffusivity (MD) in patients with neuromyelitis optica (NMO) without visible lesions on conventional brain MRI during acute relapse. Twenty one patients with NMO and 21 normal control subjects received several cognitive tests to assess cognitive function. Head diffusion tensor imaging (DTI) of all patients with NMO were collected with a 3-T MR system. Correlations of cognitive test scores and whole brain FA and MD were examined by voxel-based analysis. Region-of-interest analysis was applied to the significantly correlated regions which the most frequently appeared. We found that NMO patients without visible brain lesions had significantly impaired learning and memory, decreased information processing speed, and damaged attention compared with normal control subjects. These impaired cognitive domains were significantly correlated with FA and MD in local regions of corpus callosum, anterior cingulate and medial frontal cortex. In corpus callosum of NMO patients, mean FA was significantly lower and mean MD higher than normal control subjects. Our findings suggest that cognitive impairments in learning and memory, information processing speed and attention occur in NMO patients without visible brain lesions during acute relapse. The impairments in immediate and short-term memory in NMO patients may be due to information encoding deficits in the process of information acquisition. The corpus callosum of such patients may have local microscopic damages that play a role in cognitive impairments during acute relapse. 相似文献
Journal of Child and Family Studies - Drawing on self-determination theory and problem-behavior theory, we tested the relation between parental psychological control and adolescents’... 相似文献
Sex Roles - We introduce a new inventory measuring sex-based harassment intentions and threat perceptions grounded in gender status threat theories (Berdahl, 2007; Stephan et al., 2016). In Study 1... 相似文献
In response to the COVID-19 pandemic, restrictions on economic activities have resulted in a sharp rise of unemployment. The purpose of this research is to explore mental disorders associated with COVID-19 related unemployment using a large, nationally representative dataset, the 2020 COVID-19 Household Pulse Survey. ANOVA with post hoc tests (Tukey HSD) are utilized to reveal the mean difference of mental disorders between various employment status, as well as between reasons of unemployment. Binary logit model is used to investigate the potential effect of different reasons of unemployment on mental disorders. Individuals who were not working during the pandemic due to involuntary reasons had higher probabilities of mental disorders than those who were working and those who voluntarily separated from work. Among respondents who were not working due to COVID-19 related reasons, respondents whose employer went out of business were the most likely to experience mental disorders. Household job uncertainty in the next four weeks positively contributed to mental disorders. Government should consider measures to contain the spread of virous while keeping as many people employed as possible. Government should also consider providing adequate financial and counseling assistance to individuals who are in the greatest need for such support.
Avoidance of culturally diverse peers undermines the benefits of multicultural teams. Using uncertainty reduction theory, we argue that team members’ cultural intelligence (CQ; the capability to work effectively in culturally diverse settings) and language competence (the ability to communicate in a language) exert main and synergistic effects on avoidance behaviors. We further propose that avoidance negatively predicts individuals’ task performance (behaviors that contribute to team outcomes) and voice behaviors (giving suggestions to improve the status quo). Put together, we test a moderated mediation model where the mediating role of avoidance between CQ and outcomes of task performance and voice behaviors is moderated by language competence. Our results, based on data collected from multicultural team members at three time points, showed no main effects of CQ and language competence on avoidance. Instead, we found synergistic effects such that CQ was negatively related to avoidance only when language competence was high. Avoidance was negatively related to peer-rated task performance and voice behaviors. Conditional process analyses supported our moderated mediation hypothesis, suggesting that avoidance explains why people with higher CQ and higher language competence have higher task performance and voice behaviors. 相似文献