进化心理学对心理素质结构研究的整合与重构——以学生心理素质结构研究为例

传统的心理素质结构研究模式不经济,研究结果出现纵向断裂横向分裂的趋势.从进化心理学的视角来看,心理素质结构的最终功能均指向个体的适应性,其形成是与周围环境不断排斥和融合的过程.建构的心理素质结构融合模型能在一定程度上解决传统研究模式的弊端,并建议今后的研究应以分析人为主导转而分析人及其所处的文化环境并重,进而引导人的心理素质结构的不断发展.     

视觉刺激探测的警觉性注意特征初探

采用"预警提示-目标探测"范式,对视觉刺激探测的警觉性注意特征进行初步探索。实验一表明,随着预备到目标刺激的时间间隔(interstimulus interval,ISI)变化,固定位置上探测目标刺激的速度也随之变化,并且对大概率刺激的探测更快,表现出了警觉性注意的稳定性和选择性特征。实验二进一步考察了目标刺激在不同ISI和不同空间位置的情况,除发现与实验一相似的结果以外,被试探测目标刺激的速度随注意视角增大而下降,表现出了警觉性注意的集中性特征。     

个体对效价预期和风险评估的时程加工机制:来自ERP的证据

采用事件相关电位技术(ERP),通过简单赌博任务,操纵结果预期的效价(输或赢)与风险(高风险与低风险),考察了个体对结果预期阶段的效价和风险评估的脑内时程动态加工过程。脑电结果发现:(1)在N2成分上,结果预期的效价主效应显著,预期输比预期赢能够引起更大的N2波幅;结果预期的风险主效应不显著。(2)在N500成分上,效价与风险之间的交互作用边缘显著,进一步简单效应分析发现,在预期输的条件下,肯定会输的N500波幅显著大于可能会输;而在预期赢的条件下,肯定会赢与可能会赢之间的N500波幅差异不显著。这说明,在不确定决策过程中的结果预期阶段,个体可能先对结果预期的效价进行加工,然后再对风险进行评估。     

比较皮下注射大剂量甲氨蝶呤针与口服小剂量甲氨蝶呤片治疗类风湿关节炎疗效及安全性观察

比较皮下注射大剂量甲氨蝶呤针与口服小剂量甲氨蝶呤片分别联合小剂量醋酸泼尼松治疗类风湿关节炎的疗效及安全性差异.25例对口服小剂量甲氨蝶呤片联合小剂量醋酸泼尼松治疗3个月反应欠佳的活动性类风湿关节炎患者,将治疗方案调整为皮下注射大剂量甲氨蝾呤针联合等剂量醋酸泼尼松,回顾性分析治疗方案调整前及调整后12周时患者的肿胀关节数目、压痛关节数目、C反应蛋白、红细胞沉降率、DAS28评分及不良反应等临床及血液学指标.结果治疗方案调整后,患者压痛关节数较前减少(0.67±0.89和3.78±4.15),差异有统计学意义(P=0.043); DAS28评分较前降低(2.55±0.82和3.93±1.05),差异有统计学意义(P=0.007),严重不良反应发生率均为0％.联合小剂量醋酸泼尼松治疗类风湿关节炎,皮下注射大剂量甲氨蝶呤针疗效优于口服小剂量甲氨蝶呤片,安全性相当.     

青少年攻击行为与友谊质量的交叉滞后回归分析

该研究采用问卷法,对湖北省一所初级中学二年级青少年进行了一个学年的纵向追踪研究,使用Bjorkquist等人编制的直接和间接攻击量表(DIA)以及Parker和Asher编制的友谊质量问卷(FQQ)测查青少年的身体攻击和友谊质量。然后采用二元交叉滞后回归分析法考察了初中二、三年级学生在一个学年中的攻击行为与友谊质量(总问卷及分问卷得分)的关系。结果表明,在控制了前测"肯定与关心"得分后,身体攻击显著地负向预测了"肯定与关心"得分。在控制了前测的"冲突解决策略"得分后,攻击行为边缘显著地预测了后测的"冲突解决策略"得分。同时发现,后测"身体攻击"和"冲突与背叛"不存在显著的相关。     

伊斯兰教与世俗化问题再思考

宗教作为一种社会存在、社会文化形态,它与人类社会是双向互动的。社会生活世俗化与社会宗教道德规范化、制度化,在任何人类社会都是互有联系和区别的现象。本文以伊斯兰教历史上三个有代表性的时间节点为线索,就其与世俗化的关系问题进行了一些学理上的梳理。     

Dopamine D1 receptors are responsible for stress-induced emotional memory deficit in mice

It is established that stress impairs spatial learning and memory via the hypothalamus-pituitary-adrenal axis response. Dopamine D1 receptors were also shown to be responsible for a stress-induced deficit of working memory. However, whether stress affects the subsequent emotional learning and memory is not elucidated yet. Here, we employed the well-established one-trial step-through task to study the effect of an acute psychological stress (induced by tail hanging for 5, 10, or 20?min) on emotional learning and memory, and the possible mechanisms as well. We demonstrated that tail hanging induced an obvious stress response. Either an acute tail-hanging stress or a single dose of intraperitoneally injected dopamine D1 receptor antagonist (SCH23390) significantly decreased the step-through latency in the one-trial step-through task. However, SCH23390 prevented the acute tail-hanging stress-induced decrease in the step-through latency. In addition, the effects of tail-hanging stress and/or SCH23390 on the changes in step-through latency were not through non-memory factors such as nociceptive perception and motor function. Our data indicate that the hyperactivation of dopamine D1 receptors mediated the stress-induced deficit of emotional learning and memory. This study may have clinical significance given that psychological stress is considered to play a role in susceptibility to some mental diseases such as depression and post-traumatic stress disorder.     

Eye movements of second language learners when reading spaced and unspaced Chinese text

The effect of spacing in relation to word segmentation was examined for four groups of non-native Chinese speakers (American, Korean, Japanese, and Thai) who were learning Chinese as second language. Chinese sentences with four types of spacing information were used: unspaced text, word-spaced text, character-spaced text, and nonword-spaced text. Also, participants' native languages were different in terms of their basic characteristics: English and Korean are spaced, whereas the other two are unspaced; Japanese is character based whereas the other three are alphabetic. Thus, we assessed whether any spacing effects were modulated by native language characteristics. Eye movement measures showed least disruption to reading for word-spaced text and longer reading times for unspaced than character-spaced text, with nonword-spaced text yielding the most disruption. These effects were uninfluenced by native language (though reading times differed between groups as a result of Chinese reading experience). Demarcation of word boundaries through spacing reduces non-native readers' uncertainty about the characters that constitute a word, thereby speeding lexical identification, and in turn, reading. More generally, the results indicate that words have psychological reality for those who are learning to read Chinese as a second language, and that segmentation of text into words is more beneficial to successful comprehension than is separating individual Chinese characters with spaces.     

The impact of development of population-based study in the biomedical field on laws and regulations: a cross-strait experience on biobank development

Together with the completion of the Human Genome Project, biomedical research has marched into the "Post-Genomic Era." In order to take advantage of this extracted gene related information extensively and precisely so as to realize man's biological phenomena as well as the mechanism of pathogenesis, consequentially, a large scale sample collection of different geological areas and/or ethnic groups becomes necessary for the future population based genetic research of a country and, in turn, the construction of population-based genetic database (Biobank). In recent years, both mainland China and Taiwan have not only made great progress in information and computation technologies, but have also gradually taken a close look into the quality of medicine delivery. Thus, it becomes unavoidable for both sides to create each one's population-based genetic databases (Biobank). Theoretically speaking, the Biobank development shall benefit the study on the correlation between genes and disease and also the solution for disease treatment as well. At the same time, medical diagnostic technology has also been significantly improved. It is believable that the population-based genetic database might be utilized to promote medical quality and to reduce the cost of public health delivery. Further; in the near future, it might become the "raw materials "for medical research application. However when taking promotion of public welfare as the premises for a Biobank development, the severe and multi challenge occurred against the traditional legal rules in terms of the privacy protection, public trust development, the compliance of informed consent principle, the implementation of benefit-sharing doctrine and the possible discrimination concern about the population/participants selection and some other ELSI issues. In this paper, the major legal issues encountered by the Biobank development will first be reviewed accompanied by the background information concerning the Biobank development scenario crossing the Taiwan Strait. Also, mainly following the realm of comparative policy or legal approaches, the paper learning from the fruits of this comparative study, tries to propose some recommendations for future legislative consideration by both mainland China and Taiwan. It's been this author's wish that, when establishing a large scale population based Biobank, the promotion of public trust shall be placed as the primary goal together with the emphasis on supporting publicity and transparency on the administrative practices, so as to encourage the public participation in observing the principle of altruism and, in turn, benefit the future biomedicine development.