The objective of this study investigated cognitive impairments and their correlations with fractional anisotropy (FA) and mean diffusivity (MD) in patients with neuromyelitis optica (NMO) without visible lesions on conventional brain MRI during acute relapse. Twenty one patients with NMO and 21 normal control subjects received several cognitive tests to assess cognitive function. Head diffusion tensor imaging (DTI) of all patients with NMO were collected with a 3-T MR system. Correlations of cognitive test scores and whole brain FA and MD were examined by voxel-based analysis. Region-of-interest analysis was applied to the significantly correlated regions which the most frequently appeared. We found that NMO patients without visible brain lesions had significantly impaired learning and memory, decreased information processing speed, and damaged attention compared with normal control subjects. These impaired cognitive domains were significantly correlated with FA and MD in local regions of corpus callosum, anterior cingulate and medial frontal cortex. In corpus callosum of NMO patients, mean FA was significantly lower and mean MD higher than normal control subjects. Our findings suggest that cognitive impairments in learning and memory, information processing speed and attention occur in NMO patients without visible brain lesions during acute relapse. The impairments in immediate and short-term memory in NMO patients may be due to information encoding deficits in the process of information acquisition. The corpus callosum of such patients may have local microscopic damages that play a role in cognitive impairments during acute relapse. 相似文献
Journal of Child and Family Studies - Drawing on self-determination theory and problem-behavior theory, we tested the relation between parental psychological control and adolescents’... 相似文献
Sex Roles - We introduce a new inventory measuring sex-based harassment intentions and threat perceptions grounded in gender status threat theories (Berdahl, 2007; Stephan et al., 2016). In Study 1... 相似文献
In response to the COVID-19 pandemic, restrictions on economic activities have resulted in a sharp rise of unemployment. The purpose of this research is to explore mental disorders associated with COVID-19 related unemployment using a large, nationally representative dataset, the 2020 COVID-19 Household Pulse Survey. ANOVA with post hoc tests (Tukey HSD) are utilized to reveal the mean difference of mental disorders between various employment status, as well as between reasons of unemployment. Binary logit model is used to investigate the potential effect of different reasons of unemployment on mental disorders. Individuals who were not working during the pandemic due to involuntary reasons had higher probabilities of mental disorders than those who were working and those who voluntarily separated from work. Among respondents who were not working due to COVID-19 related reasons, respondents whose employer went out of business were the most likely to experience mental disorders. Household job uncertainty in the next four weeks positively contributed to mental disorders. Government should consider measures to contain the spread of virous while keeping as many people employed as possible. Government should also consider providing adequate financial and counseling assistance to individuals who are in the greatest need for such support.
The study aims to investigate the quality of life (QOL) and the psychological situation in Chinese patients with rosacea. A total of 196 healthy controls and 201 rosacea patients were involved in the final analysis. The general information, the Dermatology Life Quality Index (DLQI) and the Hospital Anxiety and Depression Scale (HADS) were collected. Significantly higher DLQI, anxiety and depression score were observed in the rosacea group compared to the control group (p < .01). Total DLQI score of patients was positively related with anxiety (r = .526, p < .001) and depression scores (r = .399, p < .001) in HADS. Rosacea had significant psychological impact on Chinese patients and had substantial influence on their QOL. Physicians should address the psychosocial needs of rosacea patients as much as its physical symptoms. 相似文献
To confirm the relationship between pro‐social behaviour and increased physical functioning revealed by previous researchers in Western samples, we conducted four experiments with 378 Chinese undergraduates. The participants' strength to hold, to grip and to lift, as well as their vitality (walking speed), were measured after thinking of acts of kindness. The results showed that recalling pro‐social behaviour (helping others or spending money on others) that had occurred in the past or imagining pro‐social behaviour happening in the future imbued people with more physical strength and vitality. In three experiments, pro‐social behaviour boosted the positive mood of the actors, but the effect was only significant in one experiment, suggesting that the hidden gift may include increased happiness, but that enhanced physical functioning cannot be accounted for by differences in emotions. These results add to the evidence that the function of pro‐social behaviour in promoting physical functioning may be culturally universal. 相似文献
To understand how individuals’ senses of competence are cultivated, scholars have primarily focused on situational factors such as job autonomy and supervisor support. Against this backdrop, we propose that individuals can work as active agents and enhance their sense of competence by initiating actions that aim to master the environment. We adopt the behavioral concordance model and propose that people higher in proactive personality are more likely to engage in proactive behavior that elevates their senses of competence over time. We further propose that such behavioral concordance contributes to boosting a sense of competence is more prominent among those with higher proactive personality. Our predictions are supported by data from 172 employees and their direct supervisors in China, after controlling for the effect of job autonomy and supervisor support for autonomy. Specifically, only those higher in proactive personality engaged in more proactive behavior and increased their sense of competence over time. This study highlights both a self-initiated and a behavioral perspective on understanding the development of a sense of competence. 相似文献
This article investigates how test-takers change their strategies to handle increased test difficulty. An adult sample reported their test-taking strategies immediately after completing the tasks in a reading test. Data were analyzed using structural equation modeling specifying a measurement-invariant, ability-moderated, latent transition analysis in Mplus (Muthén & Asparouhov, 2011). It was found that almost half of the test-takers (47%) changed their strategies when encountering increased task-difficulty. The changes were characterized by augmenting comprehending-meaning strategies with score-maximizing and test-wiseness strategies. Moreover, test-takers' ability was the driving influence that facilitated and/or buffered the changes. The test outcomes, when reviewed in light of adjusted test-taking strategies, demonstrated a form of process-based validity evidence. 相似文献
Attention toward social entrepreneurship has increased worldwide, particularly within younger generations. Based on the identified model of social entrepreneurial intentions, this study proposed a multiple mediation framework to examine the mediating role of entrepreneurial creativity for university students. It also compared the differences between Taiwanese (N = 311) and Hong Kong students (N = 311). Through a survey using both online and offline channels, the results of Study 1 confirmed the factor structures of the 3 scales, involving 5 antecedents of social entrepreneurial intention (i.e., empathy, moral obligation, self-efficacy, perceived social support, and prior experience with social problems), 2 factors of entrepreneurial creativity (i.e., originality and usefulness), and 2 factors of social entrepreneurial intention (i.e. conviction and preparation). The results of Study 2 supported the proposed multiple mediation model across regions. Prior experience with social problems, perceived social support, and originality were identified as the 3 most influential factors affecting the social entrepreneurial intentions of university students. The major differences between Taiwan and Hong Kong involved prior experience, empathy, self-efficacy, perceived social support, and usefulness. 相似文献