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181.
Orbital prefrontal cortex and guidance of instrumental behavior of rats by visuospatial stimuli predicting reward magnitude 下载免费PDF全文
The orbital prefrontal cortex (OPFC) is part of a circuitry mediating the perception of reward and the initiation of adaptive behavioral responses. We investigated whether the OPFC is involved in guidance of the speed of instrumental behavior by visuospatial stimuli predictive of different reward magnitudes. Unoperated rats, sham-lesioned rats, and rats with bilateral lesions of the OPFC by N-methyl-D-aspartate (NMDA) were trained in a visuospatial discrimination task. The task required a lever press on the illuminated lever of two available to obtain a food reward. Different reward magnitudes were permanently assigned to lever presses to respective sides of the operant chamber; that is, responses to one lever (e.g., the left one) were always rewarded with one pellet and responses to the other lever with five pellets. On each trial, the position of the illuminated lever was pseudorandomly determined in advance. Results revealed that OPFC lesions did not impair acquisition of the task, as the speed of conditioned responses was significantly shorter with expectancy of a high reward magnitude. In addition, during reversal, shift and reshift of lever position–reward magnitude contingencies and under extinction conditions, performance of the OPFC-lesioned and control groups did not differ. It is concluded that the OPFC in rats might not be critical for adapting behavioral responses to changes of stimulus–reward magnitude contingencies signaled by visuospatial cues. 相似文献
182.
Receiving instrumental support at work: when help is not welcome 总被引:4,自引:0,他引:4
Deelstra JT Peeters MC Schaufeli WB Stroebe W Zijlstra FR van Doornen LP 《The Journal of applied psychology》2003,88(2):324-331
Although the role of social support in promoting employees' health and well-being has been studied extensively, the evidence is inconsistent, sometimes even suggesting that social support might have negative effects. The authors examined some psychological processes that might explain such effects. On the basis of the threat-to-self-esteem model, the authors tested the hypothesis that receiving imposed support elicits negative reactions, which are moderated by someone's need for support. The authors distinguished 3 different reactions: (a) self-related, (b) interaction-related, and (c) physiological. The results of an experiment with 48 temporary administrative workers generally confirmed the hypothesis. Imposed support elicited negative reactions, except when there was an unsolvable problem, but even then the effect of imposed support was not positive but neutral. 相似文献
183.
Prinz W 《Consciousness and cognition》2003,12(4):515-528
A hypothetical evolutionary scenario is offered meant to account for the emergence of mental selves. According to the scenario, mental selves are constructed to solve a source-attribution problem. They emerge when internally generated mental contents (e.g., thoughts and goals) are treated like messages arising from external personal sources. As a result, mental contents becomes attributed to the self as an internal personal source. According to this view, subjectivity is construed outward-in, that is, one's own mental self is derived from, and is secondary to, the mental selves perceived in others. The social construction of subjectivity and selfhood relies on, and is maintained in, various discourses on subjectivity. 相似文献
184.
Wolfgang?HerzogEmail author Christoph?Nikendei Hans-Christoph?Friederich Bernd?L?we Jana?Jünger Wolfgang?Eich Stephan?Zipfel 《Psychotherapeut》2003,48(5):348-356
Zusammenfassung Die psychische Komorbidität internistischer Patienten im Sinne einer ICD-Diagnose des Kapitels F beträgt mehr als 35%: Neurotische, besonders somatoforme, Schmerz-, affektive Störungen und Suchterkrankungen sind häufig. Die Liegedauer ist bei psychischer Komorbidität deutlich erhöht. Es benötigen 5% der internistischen Patienten ein psychosomatisches Konsil. Neue, komplexe Behandlungsstrategien, wie Transplantationen, Kardioverter-Defibrillatoren, Medikamentenpumpen, erfordern häufig spezifische psychosoziale Interventionen. Ältere Patienten haben Erkrankungen, die zunehmend chronifizieren und komplexer werden. Damit werden Lebensqualität und psychische Komorbidität zu zentralen Outcomevariablen der Volkskrankheiten. Das zweite große Aufgabenfeld internistischer Psychosomatik ist die Untersuchung und die Behandlung psychosomatischer Patienten im engeren Sinne (Essstörungen, Schmerz- und somatoforme Störungen), weil internistische Diagnostik und Therapie erforderlich oder die Motivation der Patienten primär somatisch ist. Organisationsmodelle reichen von Konsil-/Liaisondiensten bis zu integrierten psychosomatischen Abteilungen oder Fachabteilungen an Allgemeinkrankenhäusern. Aussichtsreiche Forschungsstrategien werden neben der Erforschung psychosomatischer Mechanismen in der Entwicklung pragmatischer Behandlungsprogramme, ihrer Überprüfung in klinischen Studien und der Versorgungsforschung gesehen. Darüber hinaus sollte eine Intensivierung nationaler und internationaler Forschungsnetze erfolgen, wenn immer möglich unter Beteiligung anderer Disziplinen, um auch im Bereich der Forschung konkurrenzfähig zu bleiben.Herrn Prof. Dr. Ernst Richard Petzold zum 65. Geburtstag gewidmet. 相似文献
185.
186.
Wolfgang Wiltschko Russell P. Balda Mathias Jahnel Roswitha Wiltschko 《Animal cognition》1999,2(4):215-221
The role of sun compass orientation in spatial memory of Clark’s nutcrackers, Nucifraga columbiana, and pinyon jays, Gymnorhinus cyanocephalus, was studied in a series of cache recovery experiments. Birds were tested in an octagonal outdoor aviary with sand-filled
cups inserted in the floor. For caching, only 12 such cups in a 90° sector were available, while for recovery 4–7 days later
all 48 cups in the entire aviary were open. In control tests, the birds concentrated their search activity in the sector where
they had cached. When their internal clock was shifted 6 h between caching and recovery, pinyon jays shifted their search
activity to the 90° adjacent sector, as predicted if the sun compass was used. Clark’s nutcrackers did not respond to the
first clock-shift; however, they, too, shifted their search activity after a second clock-shift back to normal. This suggests
that the sun compass is a component of spatial memory in both species. Clark’s nutcrackers, however, seem to rely on their
sun compass to a lesser degree than pinyon jays or the previously studied scrub jays. A comparison of the findings indicates
that the role of the sun in spatial memory might reflect differences in habitat and ecology of the three corvid species.
Received: 18 February 1999 / Accepted after revision: 17 September 1999 相似文献
187.
188.
Alzheimer's disease (AD) is accompanied by prominent behavioural disturbances. They cause significant distress for both caregivers and patients and can play a major role in the decision to institutionalise AD patients. Recent evidence suggests that cholinergic deficiencies not only contribute to the memory and cognitive abnormalities of AD but are also responsible for some behavioural abnormalities seen over the course of the disease. In this study we assessed the ability of rivastigmine, a pseudo-irreversible cholinesterase inhibitor, to improve behavioural and psychopathologic symptoms in AD. The analysis included 34 patients present in the Germanarm of the international study B303 who received and completed long-term treatment with rivastigmine in the open-label study B305. Assessments of behaviour and psychopathological symptoms were performed using the behavioural component of the Clinicians Interview Based Impression of Change Plus (CIBIC-Plus). Results show that long-term treatment with rivastigmine can slow the progression of behavioural and psychopathological symptoms of AD. Behavioural symptoms showing stabilisation included aggressiveness, activity disturbances, hallucinations and paranoid features. Results also suggest that patients treated earlier with rivastigmine may attain a greater benefit compared with patients whose treatment is delayed 6 months. Further studies examining the effects of rivastigmine on behavioural disturbances in AD are therefore warranted. 相似文献
189.
190.
Wolfgang Schneider 《Developmental science》1998,1(2):291-297
Research on children's performance expectations has repeatedly shown that preschoolers and kindergarten children typically overestimate their own performance across a wide range of contexts. In this study, two experiments were carried out with 4- and 6-year-old children to assess the impact of familiarity with the task, memory monitoring, and wishful thinking on children's performance predictions. Results showed that overpredictions were rather due to wishful thinking than to poor metacognition, and that overpredictions were more frequent in unfamiliar as compared to familiar task settings. 相似文献