Therapeutic versus genuine cloning: what are the real moral issues?

In order to answer the question raised in the title of my paper, I first put forward a general ethical theory, which is based on the traditional maxim neminem laedere. Second, I show how this principle in conjunction with certain assumptions concerning the value of life entails certain fundamental bioethical principles. Thus killing a living being Y is morally wrong whenever the intrinsic value of the life that Y would otherwise live is positive. But procreating a living being Y is prima facie (i.e., with regard to the interests of Y) morally neutral, i.e. neither bad nor good. Third I will argue that the question of moral rights should always be reduced to the question of the morality of certain corresponding actions. In particular, granting Y a right to life should be taken to mean that it would be morally wrong if someone else were to put an end to Y's life. In a similar vein, I suggest answers to some other questions of the reproductive rights issue. Fourth, with respect to the controversial issue of genuine cloning, I do not see any compelling moral reasons against this utopian way of procreating full-grown individuals. Nevertheless, I think there are a lot of other good (pragmatic, rational) reasons not to try to produce a human Dolly. Finally, as regards the use or abuse of human embryos as potential suppliers of stem-cells for the cure of other people's diseases, it seems morally safe to perform experiments at least with those embryos which, like spare embryos that remained from measures of in vitro fertilization, would not have a life anyway. It's more difficult to decide, however, whether it would be morally safe to produce embryos (for instance through cloning) only for the sake of using them in the aforementioned way.     

There is more to anger coping than "in" or "out"

There is growing dissatisfaction with a dichotomized "anger-in" versus "anger-out" view of anger coping. Three studies using student and community adultsamples revealed a broader understanding of the nature of anger coping styles and led to the development of the new Behavioral Anger Response Questionnaire (BARQ). The BARQ is empirically derived and factorially validated and has good psychometrics. Results suggest that dichotomizing anger responses as "in" versus "out" is too coarse and that a 6-factor model may be more appropriate. The 6 factors identified here are Direct Anger-Out, Assertion, Support-Seeking, Diffusion, Avoidance, and Rumination. Women reported use of a wider range of anger coping styles, especially more social support-seeking and more use of anger diffusion strategies than men.     

Picture naming deficits in developmental dyslexia in German

Recent research with English developmental dyslexics comparing the picture naming performance of these children to the picture naming performance of non-dyslexic (‘garden variety’) poor readers, reading age matched controls and chronological age matched controls has suggested that a selective difficulty in retrieving the phonological codes of known names on demand underlies the picture naming deficit found in developmental dyslexia (Swan & Goswami, Picture naming deficits in developmental dyslexia: the phonological representations hypothesis, Brain and Language, 56 (1997), 334–353). If the underlying causal factors in dyslexia are independent of the orthography that the child is learning to read, then a difficulty in retrieving the phonological codes of known names on demand should also be found in developmental dyslexics who are learning to read other languages. We therefore set out to replicate Swan and Goswami’s study with a group of German developmental dyslexics. We were interested to see whether a phonological deficit is characteristic of dyslexia in all orthographies, even those, such as German, in which high orthographic transparency means that dyslexic children read with considerable accuracy.     

Zur Boltzmannschen Theorie des zweiten Hauptsatzes

Ohne Zusammenfassung     

Motivational reserve: motivation-related occupational abilities and risk of mild cognitive impairment and Alzheimer disease

Midlife motivational abilities, that is, skills to initiate and persevere in the implementation of goals, have been related to mental and physical health, but their association with risk of mild cognitive impairment (MCI) and Alzheimer's disease (AD) has not yet been directly investigated. This relation was examined with data from the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe). A total of 3,327 nondemented participants (50.3% of a randomly selected sample) aged 75-89 years were recruited in primary care and followed up twice (after 1.5 and 3 years). Motivation-related occupational abilities were estimated on the basis of the main occupation (assessed at follow-up II) using the Occupational Information Network (O* NET) database, which provides detailed information on worker characteristics and abilities. Cox proportional hazards models were used to evaluate the relative risk of developing MCI and AD in relation to motivation-related occupational abilities, adjusting for various covariates. Over the 3 years of follow-up, 15.2% participants developed MCI and 3.0% developed AD. In a fully adjusted model, motivation-related occupational abilities were found to be associated with a reduced risk of MCI (HR: 0.77; 95% CI: 0.64-0.92). Motivation-related occupational abilities were associated with reduced risk of AD in ApoE ε4 carriers (HR: 0.48; CI: 0.25-0.91), but not in noncarriers (HR: 0.99; CI: 0.65-1.53). These results suggest that midlife motivational abilities are associated with reduced risk of MCI in general and with reduced risk of AD in ApoE ε4 carriers. Revealing the mechanisms underlying this association may inform novel prevention strategies for decelerating cognitive decline in old age.     

Psychotherapie, Globalisierung, Hartz?IV

The mental effects of globalization, the economic crisis and unemployment must not be underestimated. In general they have to be looked upon as a complex system of structural traumatization which is causing severe psychological mental disorders, such as depression. Not only that, a psychotherapist has to pay particular attention to this. More than in physical illnesses the psychotherapist has to be solidly united with the patient, which might also result in political action.     

Goal relevance moderates evaluative conditioning effects

An important process by which preferences emerge is evaluative conditioning, defined as a change in the evaluation of a stimulus by pairing it repeatedly and consistently with an affective stimulus. The current research focuses on the role of motivation in this learning process. Specifically, it was investigated whether a conditioning procedure that is relevant to an individual's current goals is more effective than an irrelevant procedure. To this end, beverages were conditioned with either disgusted faces (relevant) or fearful faces (irrelevant). The results showed that thirsty(rather than non-thirsty) participants’ choice and evaluation of beverages were influenced by pairing beverages with disgust but not with fear. As similar results were obtained under optimal and suboptimal presentation of the conditioned stimuli, it is suggested that goals can affect automatic, associative learning, adding to the emerging body of research demonstrating that goals unconsciously affect evaluative processes.     

Changing minds in a changing world

I defend a general rule for updating beliefs that takes into account both the impact of new evidence and changes in the subject??s location. The rule combines standard conditioning with a ??shifting?? operation that moves the center of each doxastic possibility forward to the next point where information arrives. I show that well-known arguments for conditioning lead to this combination when centered information is taken into account. I also discuss how my proposal relates to other recent proposals, what results it delivers for puzzles like the Sleeping Beauty problem, and whether there are diachronic constraints on rational belief at all.