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71.
To ensure successful implementation of genetic screening and counselling according to patients best interests, the attitudes and motives of the public are important to consider. The aim of this study was to apply a theoretical framework in order to investigate which individual and disease characteristics might facilitate the uptake of genetic testing. A questionnaire using an extended version of the Theory of Planned Behaviour was developed to assess the predictive value of affective and cognitive expected outcomes, subjective norms, perceived control and uncertainty avoidance on the intention to undergo genetic testing. In addition to these individual characteristics, the predictive power of two disease characteristics was investigated by systematically varying the diseases fatality and penetrance (i.e. the probability of getting ill in case one is a mutation carrier). This resulted in four versions of the questionnaire which was mailed to a random sample of 2400 Norwegians. Results showed genetic test interest to be quite high, and to vary depending on the characteristics of the disease, with participants preferring tests for highly penetrant diseases. The most important individual predictor was uncertainty avoidance. 相似文献
72.
Medial thalamic damage is a common cause of severe memory disruption in humans. Both the anterior thalamic nuclei (ATN) and the intralaminar thalamic nuclei (ILN) have been suggested as primary sites of diencephalic injury underlying learning and memory deficits, but their respective roles have yet to be resolved. The present study explicitly compared two spatial memory tasks in male PVGc hooded rats with selective neurotoxic lesions to either (1) the ATN or (2) the rostral ILN (and adjacent lateral mediodorsal thalamic nuclei; ILN/LT lesions). As predicted, the ATN group, but not the ILN/LT group, exhibited clear deficits in the Morris water maze task for the initial acquisition of a fixed hidden platform and its reversal to a new position. The second task examined acquisition of egocentric spatial reference memory for a left or right body turn, using any three arms in an 8-arm water maze on any given trial; contrary to predictions, both lesion groups performed as well as the Sham group. The lack of deficits in ILN/LT rats on this second task contrasted with previous findings reporting a detrimental effect of ILN/LT lesions on egocentric working memory. The clear dissociation between the influence of ATN and ILN/LT lesions with respect to allocentric spatial reference memory in the Morris maze emphasizes that caution is required when interpreting the effects of non-ATN thalamic lesions on spatial memory when the lesions encroach substantial areas of the adjacent ATN region. 相似文献
73.
Does it pay to pay online panel members? A three-wave longitudinal experiment was conducted with an online panel to examine whether per person payments, paid through an online intermediary, influence response and retention rates. In the payment condition, participants were promised payment for participation at each wave, whereas control participants were not offered any payment. The promise of a payment had a negative effect on response in Wave 1, but a positive effect on response in Wave 2. Payment had no significant effect on retention. Completing a given wave was an indicator for responding to a subsequent invitation. 相似文献
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Thirty-two infants participating in a longitudinal study of the effects of premature birth on sucking and breathing were tested at 3 months post term. They were assigned at a previous test to either a healthy full-term, healthy preterm, or high risk preterm group on the basis of birth weight, postconceptional age at birth, and perinatal medical status. Positive and negative sucking pressure as well as chest and abdominal breathing movements were recorded during nutritive sucking. The high risk preterms used a simpler and more stable pattern of coordination between sucking and breathing, were more likely to interrupt breathing at milk onset, and produced longer phase lags between positive and negative sucking pressure. 相似文献
76.
This study used a repeated measures time-series design to examine the immediate and longer term impact of a structured, face-to-face developmental peer appraisal on 294 undergraduates in 44 self-managing work groups (SMWGs) and 217 MBA students in 36 SMWGs. Results revealed an immediate positive impact on perceptions of open communication, task motivation, social loafing, group viability, cohesion, and satisfaction. Also, the effects of the peer appraisal were not dependent on the perceived ratio of positive to negative feedback, and the enduring impact of the appraisal was influenced by its timing relative to task deadline. Overall, results emphasized that peer appraisals can have a positive effect on relationships and task focus, are influenced by temporal context, and have great potential for work teams. 相似文献
77.
Ann E. McCabe Joel R. Levin Peter Wolff 《Journal of experimental child psychology》1974,17(1):107-114
Nursery schooler's abilityto associate pairs of toys was assessed under four experimental conditions: (1) control, (2) S manipulating the toys, (3) S generating a sentence, and (4) S generating a sentence while manipulating the toys. All three S-involvement conditions produced significantly better recognition performance than the control but contrary to initial predictions, the difference between the sentence-only and sentence-plus-manipulation conditions was not significant. In contrast to previous research, Ss in the sentence-only conditions had little difficulty producing sentences when asked. Of interest was the finding that the quality of sentence production was poorer in the sentence-plus-manipulation condition than in the sentence-only condition. Results are discussed in terms of the possible “conflict” produced when the child is required to engage in more than one overt activity simultaneously. 相似文献
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