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401.
This study tested the hypothesis that interhemispheric communication about emotional stimuli is influenced by situational factors that alter emotional relevance. Under evaluative or nonevaluative conditions, participants matched angry and happy faces within a single visual field or across opposite visual fields. An overall across-field advantage (AFA) reflected the benefit of sharing information between the hemispheres. The AFA was greater for angry than for happy faces in the evaluation condition but did not differ for angry and happy faces in the no-evaluation condition. Examination of individual differences indicated that high trait evaluation levels of worry were associated with poorer interhemispheric communication of angry faces, supporting a threat-avoidance conception of worry. Thus, both situational factors and individual differences affected interhemispheric communication about emotional faces.  相似文献   
402.
403.
The hypothalamus pituitary adrenal (HPA)- axis is one of the major output systems of the neuroendocrine stress response. Its major end products, glucocorticoids (GCs), have a plethora of effects throughout the organism, most of which are believed to be protective against disturbances of homeostasis. However, negative effects have also been described under specific conditions of hyper- or hypo(re)activity of the HPA axis. Both beneficial and adverse effects of GCs ultimately depend on the target tissue sensitivity to these steroids. Recent findings suggest that GC sensitivity (a) may vary between different target tissues in the same organism, (b) shows large individual differences and (c) can be acutely changed in times of acute stress. In the present review, data are summarized which show differences in GC sensitivities in patients suffering from diverse somatic and psychiatric diseases, as well as chronically stressed individuals. Furthermore, studies are presented that show a rapid modulation of GC sensitivity in response to exercise or psychosocial stress in healthy adults. The response pattern of acute GC sensitivity modulation seems to be influenced by age and sex hormone status of the individual. While the GC signalling cascade may be subject to modulation at several levels, the pathway for acute modulation of GC sensitivity remains to be elucidated.  相似文献   
404.
Wolf DV  Wagner KD 《CNS spectrums》2003,8(12):954-959
There is increased recognition that bipolar disorder has an early age of onset. The prevalence of bipolar disorder in prepubertal children has not been determined, however the prevalence in adolescence is approximately 1%. Bipolar disorder in children poses a diagnostic challenge since the symptoms may differ from those in late adolescence and adulthood. Comorbid disorders, such as attention-deficit/hyperactivity disorder, further complicate both the diagnosis and course of the disorder. There is increasing evidence of the chronicity and severity of this disorder in youths. Bipolar disorder significantly disrupts a child's psychosocial development including impairments in academic functioning, family functioning, and relationship with peers. Although this disorder has significant morbidity in children and adolescents, there is a paucity of controlled studies to assess the efficacy and safety of mood stabilizers in the treatment of this disorder in youths. The treatment literature consists largely of case studies, retrospective chart reviews, and open-label studies. There is a compelling need for double-blind, placebo-controlled trials to determine whether commonly used medications to treat this disorder are significantly superior to placebo. Since many children in clinical practice require more than one psychotropic medication to adequately manage this disorder, studies of combination treatments are warranted. This review will provide an overview of the literature of bipolar disorder in children and adolescents, including discussion of the prevalence, diagnosis, epidemiology, course of the illness, and treatment issues.  相似文献   
405.
Among the problems of understanding mental pathology through a labeling perspective is the need to understand more about the attributional process itself. It is postulated that characteristics of observers, in particular their attitudes, influence the attribution of mental disorder to individuals manifesting deviant behavior. Questionnaire items were factor analyzed to produce several dimensions of attitudes and types of deviance. Tests of seven sub‐hypotheses provide support for the major hypothesis that the probability mental disorder will be attributed by an observer to an actor is positively related to the degree an actor's behavior (implying beliefs or attitudes) differs from the beliefs and attitudes of the observer.  相似文献   
406.

We use molecular dynamics simulations to elucidate the transition with decreasing grain size from a dislocation- to a grain-boundary-based deformation mechanism in nanocrystalline fcc metals. Our simulations reveal that this crossover is accompanied by a pronounced transition in the mechanical behaviour of the material; namely, at the grain size where the crossover occurs (the 'strongest size'), the strain rate under tensile elongation goes through a minimum. This simultaneous transition in both the deformation mechanism and the corresponding mechanical behaviour offers an explanation for the experimentally observed crossover in the yield strength of nanocrystalline materials, from Hall-Petch hardening to 'inverse Hall-Petch' softening.  相似文献   
407.
Two alternative scenarios on the future of the nation state are presented in order to discuss the concepts of national identity as well as of political system legitimacy. At the core is the question to what extent the nation state will become obsolescent if not obsolete as a function of international interdependence. Fukuyama considers national identity a cultural phenomenon alien to democracy as the ultimate form of government. Guéhenno, in contrast, believes that the erosion of the nation state and of national identity will bring about the end of democracy. The disagreement rests on the assumption whether the political systems will be able to retain their autonomy allowing them to maintain or expand individual liberty and collective freedom.  相似文献   
408.
This study examined the potentially compounding effect of language minority (LM) status on problem behaviors among urban second and third grade-level poor readers. Univariate analyses showed that a disproportionate percentage of both LM and English monolingual (L1) poor readers already displayed clinically significant levels of anxiety, social problems, and oppositional behaviors in the classroom. Analyses of variance, however, demonstrated that LM status was not an additive risk factor for reading difficulties, behavior problems, or lowered self-concept in this sample. No differences were observed between LM and L1 students on a wide range of reading measures, on their teachers’ ratings of internalizing and externalizing problem behaviors in the classroom, or on self-ratings of self-efficacy and social competence. Implications for intervention for all urban students with reading difficulties are discussed.  相似文献   
409.
In a recent paper entitled “Mirror Neurons. Procedural Learning and the Positive New Experience” (Wolf et al., 2000), data were presented about a special type of neuron, the mirror neuron, originally located by Rizzolatti and his colleagues (1995). These neurons were discussed as they related to a particular developmental view of psychoanalysis, developmental systems self psychology (Shane, Shane, and Gales. 1997).

In this paper, we focus on how this mirror neuron system might contribute to the development of communicative abilities in humans. First we summarize the research findings about mirror neurons and how they apply to humans. We then attempt to demonstrate how the mirror neuron system might be involved in a developmental sequence hypothesized by Kohut (1984), Stern (1985), and others to begin in infancy. We postulate that this trajectory starts with the onset of “amodal perception” (Stern, 1985) and then proceeds to affect resonance, joint attention, and ultimately to symbolization of language. In this paper, we attempt to integrate these concepts with a formulation of empathy and demonstrate what might go awry in developmental disorders when the normative sequence of development described above does not take place.  相似文献   
410.
Augmented feedback, provided by coaches or displays, is a well-established strategy to accelerate motor learning. Frequent terminal feedback and concurrent feedback have been shown to be detrimental for simple motor task learning but supportive for complex motor task learning. However, conclusions on optimal feedback strategies have been mainly drawn from studies on artificial laboratory tasks with visual feedback only. Therefore, the authors compared the effectiveness of learning a complex, 3-dimensional rowing-type task with either concurrent visual, auditory, or haptic feedback to self-controlled terminal visual feedback. Results revealed that terminal visual feedback was most effective because it emphasized the internalization of task-relevant aspects. In contrast, concurrent feedback fostered the correction of task-irrelevant errors, which hindered learning. The concurrent visual and haptic feedback group performed much better during training with the feedback than in nonfeedback trials. Auditory feedback based on sonification of the movement error was not practical for training the 3-dimensional movement for most participants. Concurrent multimodal feedback in combination with terminal feedback may be most effective, especially if the feedback strategy is adapted to individual preferences and skill level.  相似文献   
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