医师协会行业自律：医学伦理建设的一个有效机制

中国医师协会自2002年成立以来,做了大量工作,但其主要集中在维护医师权益方面,在自律建设方面却作为不够。医师协会加强行业自律方可有效维权,这是医师协会开展工作的一种策略。在此基础上,进一步研究了"加强行业自律"这个医学伦理建设的有效机制。     

RNA干扰现象研究获诺贝尔奖的启示

RNA干扰现象是目前生命科学领域的研究热点.由于RNA干扰具有十分重要的理论和应用价值,因此该现象在揭示后仅8年其研究者就获得了诺贝尔生理与医学奖.通过回顾RNA干扰现象的发现历程,可以为今后的科研探索过程提供许多有益的启示.     

ICQ (I seek you) and adolescents: a quantitative study in Hong Kong.

The Hong Kong Government and the education sector encourage the whole population-from toddlers to senior citizens-to utilize information technology, and many do. Yet there are no studies exploring the patterns of adolescents using ICQ (I seek you) in Asian countries. This study was done in Hong Kong, which has the greatest number of ICQ users. A quantitative approach was adopted by administering self-constructed questionnaires to the students of one high school. One hundred and forty-seven adolescents volunteered to participate. The key findings of the study are (1) most of the adolescents have been using ICQ for 1-4 years; (2) most fit one of two patterns of use: either 2 or 3 days per week, or more than 5 days per week; (3) they spend less than 3 h per day on ICQ; (4) the main reasons for using ICQ are entertainment, relaxation, and socializing; and (5) parents are concerned about possible negative impacts on their children's academic performance because of using ICQ. Two main implications are drawn: proper use of ICQ can minimize parental distress and encourage adolescents to be less sedentary.     

VR-based conversation training program for patients with schizophrenia: a preliminary clinical trial.

Schizophrenia is a devastating mental illness and is characterized by hallucinations and delusions as well as social skills deficits. Generally, social skills training designed to help patients develop social skills includes role-playing, but this form of training has typical shortcomings, which are largely due to a trainer's difficulties to project emotion. Virtual reality (VR)-based techniques have the potential to solve these difficulties, because they provide a computer-generated but realistic three-dimensional world and humanlike avatars that can provide emotional stimuli. In this paper, we report on a method of implementing virtual environments (VEs) in order to train people with schizophrenia to develop conversational skills in specific situations, which could overcome the shortcomings of or complement conventional role-playing techniques. The paper reports the efficacy of the proposed approach in a preliminary clinical trial with 10 patients with schizophrenia.     

Recalling a Witnessed Event Increases Eyewitness Suggestibility: The Reversed Testing Effect

ABSTRACT— People's later memory of an event can be altered by exposure to misinformation about that event. The typical misinformation paradigm, however, does not include a recall test prior to the introduction of misinformation, contrary to what real-life eyewitnesses encounter when they report to a 911 operator or crime-scene officer. Because retrieval is a powerful memory enhancer (the testing effect), recalling a witnessed event prior to receiving misinformation about it should reduce eyewitness suggestibility. We show, however, that immediate cued recall actually exacerbates the later misinformation effect for both younger and older adults. The reversed testing effect we observed was based on two mechanisms: First, immediate cued recall enhanced learning of the misinformation; second, the initially recalled details became particularly susceptible to interference from later misinformation, a finding suggesting that even human episodic memory may undergo a reconsolidation process. These results show that real-life eyewitness memory may be even more susceptible to misinformation than is currently envisioned.     

社会支持与心血管反应的实验室研究概述

从20世纪70年代起国内外学者开始兴起了对社会支持的研究,而对社会支持与心血管健康的关系研究一直都是社会支持研究领域中的重要课题。本文回顾了社会支持在心血管反应的实验室研究中操作性的定义;实验室研究中社会支持与心血管健康的关系、社会支持对心血管反应作用的影响因素、社会支持的作用机制、社会支持的测量方法及社会支持与心血管反应实验室研究的局限性。     

Spatial working memory maintenance: Does attention play a role? A visual search study

Recent studies have proposed that a common mechanism may underlie spatial attention and spatial working memory. One proposal is that spatial working memory is maintained by attention-based rehearsal [Awh, E., Jonides, J., & Reuter-Lorenz, P. A. (1998). Rehearsal in spatial working memory. Journal of Experimental Psychology: Human Perception and Performance, 24(3), 780-790], and so a spatial attention shift during the retention interval of a spatial location should impair its memory performance. In the present study, participants engaged in single-item, parallel or serial search tasks while remembering a spatial location. Although memory tended to bias all searches, the need for an attentional shift during the retention interval impaired memory performance only in single-item search, but not in other searches. These findings suggest that previous evidence for the attention-based rehearsal account does not generalize to visual search. Results are discussed with regard to the relationship between spatial attention and spatial working memory.     

Self‐esteem as a source of evaluative conditioning

This study was designed to examine whether self‐esteem can be used as a source of evaluative conditioning, and whether implicit or explicit self‐esteem was more predictive of the evaluative conditioning effect. Moreover, the role of contingency awareness in the acquisition of the evaluative conditioning effect was also examined. Words related to the self and a general other were served as unconditioned stimuli (USs) in the evaluative conditioning process in order to see whether the evaluation could be transferred to neutral, abstract paintings after 10 times of pairing. An evaluative conditioning effect was demonstrated in that the evaluation of the paintings became more positive after repeatedly paired with words about the self but not words about general others. Implicit self‐esteem predicted the magnitude of the evaluative conditioning effect, while the association between explicit self‐esteem and the evaluative conditioning effect was nonsignificant, both with and without the effect of contingency awareness being controlled for. Copyright © 2009 John Wiley & Sons, Ltd.     

Neural correlates of Traditional Chinese Medicine induced advantageous risk-taking decision making

This fMRI study examined the neural correlates of the observed improvement in advantageous risk-taking behavior, as measured by the number of adjusted pumps in the Balloon Analogue Risk Task (BART), following a 60-day course of a Traditional Chinese Medicine (TCM) recipe, specifically designed to regulate impulsiveness in order to modulate risk-taking behavior. The 14 participants recruited for this study were randomly assigned to the experimental and control groups and the TCM recipe (Panax, 520 mg; Astragalus membranaceous Bunge, 520 mg; Masnetitum, 840 mg; Ostrea gigas Thumb, 470 mg; Thinleaf Milkwort Root Radix Polygalae, 450 mg; and Os Draconis, 470 mg) was administered, as a diet supplement, to the seven participants in the experimental group. The neural activity of the two groups was monitored by a 3T MRI scanner, before and after the 60-day treatment. Associated with the improved advantageous risk-taking behavior seen in the experimental group, significantly stronger blood oxygenation level dependent (BOLD) responses were observed in the bilateral dorsolateral prefrontal cortex (DLPFC), left putamen, left thalamus, right insula, and right anterior cingulate cortex (ACC), regions which have previously been reported as being involved in risk-taking decision making. The effect of the TCM in improving advantageous risk-taking decision making appears to have been related to the enhanced efficiency of the cognitive affective system, the PFC–ACC–insula–striatum network, which functions to inhibit impulsiveness, to sensitize reward-related information, and to allow the opportunity, during risk estimation, to evaluate potential gains and losses. The findings of this study suggest that interventions acting on factors modulating risk-taking decision making could have a beneficial effect in terms of optimizing risk-taking behavior.     

儿童注意力检测单片机的研制及动态分析指标的试用

儿童注意力的测量途径包括家长或教师评定法、行为观察法、生理检测法及实验室测量法等。在实验室测量法中,持续性操作测试（CPT技术）是主要的测量范式。传统的CPT技术主要应用漏报率和误报率作为评价指标。但是,由于注意不是静态的,而是一个高度动态和波动的过程,漏报率和误报率还不足以反映注意状态的动态变化。近年来的国外研究发现,把注意作为一个动态的现时过程来评估,以儿童在作业中反应状态的波动情况作为新的指标能提供更有价值的信息。本研究以此为依据,开发研制了基于CPT技术的儿童注意力检测单片机SCM-CPT测试仪,在测试结果处理上采用了新的动态分析指标,在98名普通小学生中进行了试用,并为新指标建立了参考性评价标准。