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921.
Neural localization of semantic context effects in electromagnetic and hemodynamic studies 总被引:5,自引:0,他引:5
Measures of electrical brain activity (event-related potentials, ERPs) have been useful in understanding language processing for several decades. Extant data suggest that the amplitude of the N400 component of the ERP is a general index of the ease or difficulty of retrieving stored conceptual knowledge associated with a word, which is dependent on both the stored representation itself, and the retrieval cues provided by the preceding context. Recordings from patients with brain damage, intracranial recordings, and magnetoencephalographic data implicate a (probably large portion of) the left temporal lobe as the largest source of the N400 semantic context effect, with a substantial but lesser contribution from the right temporal lobe. Event-related functional magnetic resonance (fMRI) studies using semantic context manipulations are dominated by observations of greater hemodynamic activity for incongruent sentence completions or semantically unrelated words than congruent or related words, consistent with the direction of the ERP effect. The locations of the hemodynamic effects show some variability across studies, but one commonly identified region is the left superior temporal gyrus, which is compatible with the electrophysiological results. A second commonly identified region in the fMRI studies is the left inferior frontal gyrus, which does not appear to make a substantial contribution to the N400 effect. 相似文献
922.
Van Lancker Sidtis D 《Brain and language》2006,98(3):276-290
Neurolinguistic research has been engaged in evaluating models of language using measures from brain structure and function, and/or in investigating brain structure and function with respect to language representation using proposed models of language. While the aphasiological strategy, which classifies aphasias based on performance modality and a few linguistic variables, has been the most stable, cognitive neurolinguistics has had less success in reliably associating more elaborately proposed levels and units of language models with brain structure. Functional imaging emerged at this stage of neurolinguistic research. In this review article, it is proposed that the often-inconsistent superfluity of outcomes arising from functional imaging studies of language awaits adjustment at both "ends" of the process: model and data. Assumptions that our current language models consistently and reliably represent implicit knowledge within human cerebral processing are in line for major revision; and the promise of functional brain imaging to reveal any such knowledge structures must incorporate stable correlates of the imaging signal as dependent variable. 相似文献
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Within (and between) cultures, people tend to agree on which parts of colour space are easiest to name and what the names for these regions are. Therefore it is likely that the manipulation of ease of naming (nameability) of colours should change performance in tasks where categorisation by colour name is important. More specifically? highly 'nameable' colour sets should lead to better performance than metrically equivalent but less categorically distinct sets, when the task requires categorisation. This hypothesis was investigated by testing observers on a name-based task, the naming and subsequent identification by name of colour sets with up to sixteen members. These sets were designed to be easy to name (nameable), maximally discriminable, or matched discriminable. The first were derived from previously generated data, the second by a standard algorithm to space colours widely in colour space, and the latter by closely matching their metric characteristics to those of an easy-to-name colour set. This final condition was metrically (but not categorically) equivalent to the nameable set. It was found that sets designed to be nameable did indeed lead to superior performance as measured by response times, confidence ratings, and response accuracy. Perceptual colour similarity, measured by a AE metric, did not predict errors. Nameability may thus be a valid, manipulable, aspect of sets of colours, and one which is not otherwise duplicated in the metric characteristics of such sets. 相似文献
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van den Buuse M 《Stress (Amsterdam, Netherlands)》2002,5(3):227-231
Cardiac hemodynamic mechanisms involved in cardiovascular responses to stress were studied in conscious, freely-moving female spontaneously hypertensive rats exposed for 15 min to an open-field. When pretreated with saline, the rats displayed a rapid rise in blood pressure, heart rate, aortic dP/dt and locomotor activity. In rats pretreated with 0.5 mg/kg of methylatropine, the tachycardia was slightly, but significantly reduced. In rats pretreated with 1 mg/kg of atenolol, the tachycardis and rise in dP/dt were markedly reduced. These data suggest that the cardiac responses to stress include predominantly cardiac sympathetic activation and a minor component of vagal withdrawal. 相似文献