Development and Pilot Testing of a Decision Aid for Genomic Research Participants Notified of Clinically Actionable Research Findings for Cancer Risk

Germline genomic testing is increasingly used in research to identify genetic causes of disease, including cancer. However, there is evidence that individuals who are notified of clinically actionable research findings have difficulty making informed decisions regarding uptake of genetic counseling for these findings. This study aimed to produce and pilot test a decision aid to assist participants in genomic research studies who are notified of clinically actionable research findings to make informed choices regarding uptake of genetic counseling. Development was guided by published literature, the International Patient Decision Aid Standards, and the expertise of a steering committee of clinicians, researchers, and consumers. Decision aid acceptability was assessed by self-report questionnaire. All 19 participants stated that the decision aid was easy to read, clearly presented, increased their understanding of the implications of taking up research findings, and would be helpful in decision-making. While low to moderate levels of distress/worry were reported after reading the booklet, a majority of participants also reported feeling reassured. All participants would recommend the booklet to others considering uptake of clinically actionable research findings. Results indicate the decision aid is acceptable to the target audience, with potential as a useful decision support tool for genomic research participants.     

A Phenomenological Inquiry of Identity Development,Same‐Sex Attraction,and Religious Upbringing

Growing up in religious/spiritual communities often creates identity issues for lesbian and gay individuals. In this phenomenological study, the authors investigated the experiences of 25 lesbian and gay individuals who self‐identified as having been raised within organized religious communities. Participants described that these communities were affirming, tolerant, or nonaffirming. Accordingly, emergent themes indicated that the current spiritual lives of participants varied greatly depending on their experiences of identity integration and affirmation. Implications for counselors and researchers are discussed.     

Competence in everyday activities as a predictor of cognitive risk and mortality

This study examined the association of a performance-based measure of everyday functioning with clinically meaningful outcomes. Elderly participants in a prospective study of dementia were assessed at two occasions on the Everyday Problems Test for Cognitively Challenged Elderly (EPCCE), a performance-based measure of everyday functioning. Older adults who remained cognitively intact performed approximately 0.66 SD units higher on the EPCCE at both occasions than elders rated as impaired, when covarying on age, education, gender, and cognitive status. Relative to the nonimpaired participants, decline in EPCCE performance over a 2-year interval was significantly greater for impaired participants and those participants who transitioned from nonimpaired to impaired over the course of the study. Increased risk of mortality was associated with lower baseline scores and decline in EPCCE performance even after controlling for demographic variables and performance on the Mini-Mental State Examination. Given the clinical importance of identifying "at risk" elders for impairment, the findings from this study provide initial evidence for the predictive utility of performance-based measures of everyday functioning.     

Acceptance patterns of retaliatory aggression among adjudicated youth by sex and race

This study investigates sex and race differences in normative beliefs about the acceptability of aggression across dimensions of severity of provocation (weak versus strong) and sex of provoker (male versus female). Students in the sample of 311 included those required to attend three Department of Youth Services schools after placement by the juvenile court system from across the state of Alabama (N=392). Results show that males were significantly more likely than females to approve of retaliation to weak provocation and against females. There were no significant differences between males and females for retaliation with strong provocation and against males. Results also show the Black group was significantly more likely than the White group to approve of retaliation to weak provocation, strong provocation, and against females.     

Large-scale neural network for sentence processing

Our model of sentence comprehension includes at least grammatical processes important for structure-building, and executive resources such as working memory that support these grammatical processes. We hypothesized that a core network of brain regions supports grammatical processes, and that additional brain regions are activated depending on the working memory demands associated with processing a particular grammatical feature. We used functional magnetic resonance imaging (fMRI) to test this hypothesis by comparing cortical activation patterns during coherence judgments of sentences with three different syntactic features. We found activation of the ventral portion of left inferior frontal cortex during judgments of violations of each grammatical feature. Increased recruitment of the dorsal portion of left inferior frontal cortex was seen during judgments of violations of specific grammatical features that appear to involve a more prominent working memory component. Left posterolateral temporal cortex and anterior cingulate were also implicated in judging some of the grammatical features. Our observations are consistent with a large-scale neural network for sentence processing that includes a core set of regions for detecting and repairing several different kinds of grammatical features, and additional regions that appear to participate depending on the working memory demands associated with processing a particular grammatical feature.     

Social power increases implicit prejudice

The effects of power on implicit and explicit attitudes towards racial groups were examined. In Study 1, participants who had power showed a stronger facilitation of positive words after exposure to White faces, and negative words after exposure to Black faces, compared to participants who did not have power. In Study 2, powerful participants, compared to controls and powerless participants, showed more positive affective responses to Chinese pictographs that followed White compared to Black faces. Power did, however, not affect explicit racial attitudes. In Study 3, powerful participants showed greater racial prejudice toward Arabs in an Implicit Association Test than did powerless participants. This effect was driven by the power of the perceiver rather than the power of the target. Implications of these findings are discussed.     

Attributions for Expectancy Violating Changes in Affectionate Behavior in Platonic Friendships

Although affectionate communication is vital for the maintenance of close, personal relationships, it has the potential to generate negative as well as positive outcomes, which may in part be a function of what attributions are made for affectionate expressions. The present experiment applied principles of attribution theory to unexpected changes in affectionate communication within dyads of adult platonic friends. Results indicated that attributions are more often made for decreases in affection than for increases. Contrary to the prediction of the fundamental attribution error, all the participants more often made external, noncontrollable attributions for changes in affectionate behavior, and the intimacy level of the friendship moderated this effect. Finally, the types of attributions made were associated with a recipient's evaluations of the giver's affectionate behavior and his or her assessment of the giver's character.     

Psychological consequences of collective violence in childhood: the case of Monterrey,Mexico / Consecuencias psicológicas de la violencia colectiva en la niñez: el caso de Monterrey,México

Abstract

During the last years, different types of violence have severely damaged Mexico. In this paper we examine the consequences that violence could have in children, one of the most vulnerable segments of society. In short, we predict that exposure to any type of violence will lead to higher depression and that this could be explained through the effects of violence on childhood well-being. Our hypothesis was supported in two studies, showing that exposure to street violence (Study 1, N = 607) and exposure to collective violence (Study 2, N = 172) can increase childhood depression. Moreover, in both studies, this effect was explained by the decrease of childhood well-being caused by violence exposure. The implications of these results are discussed.     

Creating a sustainable global society— the evolutionary path

Many indicators suggest that modern society is presently in a period of transition. The older order is showing obvious signs of decline, and elements of a new order appear to be forming. Growing numbers of people are coming to recognize that the worsening global dilemmas are best viewed as symptoms of an underlying disorder involving some of the most deeply underlying assumptions of modern society. The ultimate resolution of these dilemmas will come about, not through politically implemented “solutions,” but through our further evolution to a fundamentally different, “trans‐modern” society. The key challenge to individuals and organizations is to understand the necessary evolutionary change well enough to contribute toward its taking place with a minimum of attendant social disruption and human misery.     

Strategy Use in Reasoning Training With Older Adults

The relationship between strategy use and cognitive training gains on reasoning ability is examined in a sample of 393 older participants in the Seattle Longitudinal Training Study. Pre- and posttest gains on the use of strategies specific to reasoning ability were compared for the elderly trained on reasoning versus spatial orientation ability. The present study involves an objective behavioral method of measuring strategy use on tests of inductive reasoning. Results showed that participants trained on reasoning significantly increased strategy use from pre- to posttest on two reasoning outcome measures compared to participants trained on spatial orientation. Higher strategy use by inductive reasoning trainees was also associated with greater training gain on reasoning outcome measures, suggesting strategy use as a possible mechanism of training gain. In addition, young–old participants and those with higher education, irrespective of training condition, exhibited greater pre- to posttest gain in strategy use.