Olfactory learning in individually assayed Drosophila larvae

Insect and mammalian olfactory systems are strikingly similar. Therefore, Drosophila can be used as a simple model for olfaction and olfactory learning. The brain of adult Drosophila, however, is still complex. We therefore chose to work on the larva with its yet simpler but adult-like olfactory system and provide evidence for olfactory learning in individually assayed Drosophila larvae. We developed a differential conditioning paradigm in which odorants are paired with positive (“+” fructose) or negative (“-” quinine or sodium chloride) gustatory reinforcers. Test performance of individuals from two treatment conditions is compared—one received odorant A with the positive reinforcer and odorant B with a negative reinforcer (A+/B-); animals from the other treatment condition were trained reciprocally (A-/B+). During test, differences in choice between A and B of individuals having undergone either A+/B- or A-/B+ training therefore indicate associative learning. We provide such evidence for both combinations of reinforcers; this was replicable across repetitions, laboratories, and experimenters. We further show that breaks improve performance, in accord with basic principles of associative learning. The present individual assay will facilitate electrophysiological studies, which necessarily use individuals. As such approaches are established for the larval neuromuscular synapse, but not in adults, an individual larval learning paradigm will serve to link behavioral levels of analysis to synaptic physiology.     

Frontal lobe dysfunctions in borderline personality disorder? Neuropsychological findings

This study aims to determine whether specific neuropsychological performance impairments in borderline patients can be objectified and whether these findings indicate frontal dysfunctions. Twenty-three patients with borderline personality disorder and 23 normal controls were examined using a neuropsychological test battery to assess intelligence, attentiveness, proneness to interference, learning and memory, as well as planning and problem solving. All subjects filled out standardized questionnaires to assess aggressiveness and impulsiveness in the context of these cognitive performance areas. The neuropsychological test results of the borderline patients were comparable to those of the controls. Although there were no indications of frontal dysfunction of cognitive information processing, inverse correlations were found between the severity of borderline-related personality traits regarding impulsiveness and various areas of cognitive performance. Borderline personality patients show no indications of frontal cognitive dysfunction. Further research is needed to clarify the relationship between impulsiveness and cognitive information processing in borderline personality disorder, including a dimensional approach to personality and personality disorder.     

The contribution of EEG coherence to the investigation of language

The contribution of EEG coherence analysis to the investigation of cognition and, in particular, language processing is demonstrated with examples of recent EEG studies. The concept of EEG coherence analysis is explained, and its importance emphasized in the light of recent neurobiological findings on frequency-dependent synchrony as a code of information processing between nerve cell assemblies. Furthermore, EEG coherence studies on naturally spoken and written word and sentence processing are reviewed and experimental results are presented giving new insights into the occurrence of "transient functional language centers" within the brain.     

An exploration of links between early parenting experiences and personality disorder type and disordered personality functioning

Reports of early parenting were assessed using two measures, the Parental Bonding Index (PBI) and the Measure of Parenting Style (MOPS), in a sample of 265 patients with DSM-defined major depressive disorder. Psychiatrists then rated the extent to which sample members evidenced the personality "styles" underpinning 15 separate personality disorders, returning personality vignette scores. The extent of disordered functioning was also assessed across "parameters" and "domains" by psychiatrists, referrers, and family members, using a range of measures. Those with higher scores on vignettes measuring borderline, anxious, depressive, and self-defeating personality style rated parents as uncaring, overcontrolling, and abusive. When vignettes were consolidated into scores akin to the DSM clusters, the most consistent links between perceived dysfunctional parenting were with the Cluster C (anxious), and Cluster B (dramatic) styles and were nonsignificant for Cluster A (eccentric) style. Meeting criteria for an increasing number of personality disorder clusters was associated with increasing levels of adverse parenting. Multiple regression analyses indicated that disordered functioning (as assessed by the three independent rater groups) was most distinctly associated with paternal indifference and maternal overcontrol.     

The evolution of Crew Resource Management training in commercial aviation

In this study, we describe changes in the nature of Crew Resource Management (CRM) training in commercial aviation, including its shift from cockpit to crew resource management. Validation of the impact of CRM is discussed. Limitations of CRM, including lack of cross-cultural generality are considered. An overarching framework that stresses error management to increase acceptance of CRM concepts is presented. The error management approach defines behavioral strategies taught in CRM as error countermeasures that are employed to avoid error, to trap errors committed, and to mitigate the consequences of error.     

Reading Aloud from Logographic and Alphabetic Texts: Comparisons Between Chinese and German

The following study investigated the effect of writing systems (logographic vs. alphabetic) on the temporal organization of reading aloud. More specifically, we wished to test Perfetti and Zhang's (1995) assertion that the reader of an alphabetic system can do better at recovering the phonological form, less well at recovering the semantic category of the word (p. 186f.). Native speakers of Chinese and German read a semantically identical passage from texts written in their own language. The Chinese version consisted of 132 characters (132 syllables), the German of 80 words (also 132 syllables). In accord with Perfetti and Zhang's position, Chinese readers articulated significantly more slowly; they also used significantly more pauses. Moreover, German readers used a set pattern of pause positions, whereas Chinese did not. Logographic and alphabetic determinants of reading aloud are discussed.     

Validation of the German version of Cloninger's TPQ: Replication and correlations with stress coping, mood measures and drug use

The tridimensional personality questionnaire (TPQ) was developed by Cloninger (1986, 1987a) to measure the independent personality dimensions Novelty Seeking (NS), Harm Avoidance (HA) and Reward Dependence (RD). After having investigated the basic psychometric properties of a German version of the TPQ in a first study (Weyers et al., 1995), a new sample of 200 subjects was collected to investigate the reliability of the results of this first study and to add further validity data by including measures of stress coping, mood and drug use. In general, the results of the first study were replicated. The internal consistencies of the superscales NS, HA and RD were high, and a factor analysis of the TPQ subscales yielded some support for Cloninger's personality theory. Because of its strong correlations with Psychoticism, Extraversion, Impulsiveness and Sensation Seeking NS seems to tap an impulsivity factor while HA correlates with Neuroticism and Introversion and appears to measure a behavioral inhibition factor, the latter interpretation being supported by correlations between HA and some mood measures like anxiety and self-confidence. In addition, HA showed substantial positive correlations with coping strategies like Rumination, Resignation and Self-pity and substantial negative correlations with strategies like Self-aggrandizement by Comparison with Others and Positive Self-instructions, while the other two TPQ superscales hardly correlate with any of the coping strategies measured. With respect to drug use, only NS showed small but substantial bivariate correlations with the use of nicotine and psychodysleptics for the last 12 weeks and last 2 years. However, a configurational analysis of the TPQ superscales demonstrated that the type II alcoholism pattern proposed by Cloninger (high NS, low HA and low RD) was associated with a strong alcohol consumption.     

Effectiveness of an attachment-based intervention for the assessment of parenting capacities in maltreating families: A randomized controlled trial

Even though Parenting Capacity Assessments (PCAs) are essential for child protection services to support placement decisions for maltreating families, presently no evidence-based PCA protocols are available. In this randomized controlled trial, we tested the quality of an attachment-based PCA protocol based on Video-feedback Intervention to promote Positive Parenting and Sensitive Discipline (VIPP-SD). We recruited 56 parent-child dyads (M_age children = 3.48 years) in Dutch family residential clinics that conduct PCAs to support placement decisions. After pretest, families were randomized to receive the Regular Assessment Procedure (RAP) (n = 28), or an additional assessment based on VIPP-SD (n = 28). An immediate post-test and a 10-month follow-up were conducted. Multilevel models showed that therapists felt equally confident about their recommendations regarding child placement for both groups and that they equally often modified their initial placement recommendations. Moreover, children in the VIPP-SD group did not show fewer behavior problems and did not experience recurring child maltreatment less often than children in the RAP group. Thus, we found no evidence that PCAs incorporating the VIPP-SD protocol outperformed PCAs as usual. We discuss possible explanations why in the current study VIPP-SD did not seem to add to the quality of the RAP.