Determination of dipeptidyl aminopeptidase activities in the cerebrospinal fluid

The investigation of enzyme activity in cerebrospinal fluid has been without relevant results for laboratories analysing spinal fluid. For neurochemical purposes, it is interesting that the Substance P is convered by Depeptidyl-aminopeptidase IV (DP IV), liberating dipeptides. The hydrolysis of nitroanilids of the form Xaa-Pro-NHNp in cerebrospinal fluid was analysed using them as peptidases substrates. Finally a method for measuring the activity was proposed.     

Smoking and pain--a method of limits and sensory decision theory analysis

The effects of tobacco smoking on responses to electrical stimulation were studied according to a Method of Limits (ML) threshold analysis and a Sensory Decision Theory (SDT) analysis. For the ML procedure, Detection Threshold (DT), Pain Threshold (PT) and Tolerance Level (TL) measures were obtained. For the SDT procedure, nonparametric estimates of capacity to discriminate between stimulus intensities (P(A)) and response criterion (B) were calculated. There was no main effect of tobacco smoking on responses to electrical stimulation. Males had consistently higher ML thresholds than females in both the NS and S condition. Males also tended to increase in DT and PT after smoking. From a comparison between the effects of smoking on ML and SDT measures it was suggested that PT is related mainly to sensory factors and TL to response factors.     

Constrained classification: The use of a priori information in cluster analysis

In many classification problems, one often possesses external and/or internal information concerning the objects or units to be analyzed which makes it appropriate to impose constraints on the set of allowable classifications and their characteristics. CONCLUS, or CONstrained CLUStering, is a new methodology devised to perform constrained classification in either an overlapping or nonoverlapping (hierarchical or nonhierarchial) manner. This paper initially reviews the related classification literature. A discussion of the use of constraints in clustering problems is then presented. The CONCLUS model and algorithm are described in detail, as well as their flexibility for use in various applications. Monte Carlo results are presented for two synthetic data sets with appropriate discussion of the resulting implications. An illustration of CONCLUS is presented with respect to a sales territory design problem where the objects classified are various Forbes-500 companies. Finally, the discussion section highlights the main contribution of the paper and offers some areas for future research.We wish to thank C. Mallows and J. D. Carroll for some helpful technical discussion and L. Clark and D. Art for their valuable computer assistance. We also wish to thank H. Pollak, R. Gnanadesikan, and J. Kettenring for their thorough reviews of a previous draft of this paper. Finally, we acknowledge helpful comments of the editor and two anonymous reviewers.     

The St. Pauls' riot: An explanation of the limits of crowd action in terms of a social identity model

The paper contains a detailed study of the St. Pauls' riots of April 1980. Particular attention is paid to the limits of participation in the event and the limits of crowd action. It is argued that these limits show clear social form and cannot be explained in terms of the individualistic theories that dominate crowd psychology. Instead a model of crowd behaviour based on the social identity model is advanced to account for the observations. It is concluded that crowd behaviour is more sophisticated and creative than hitherto allowed and that the neglect of this field should be remedied.     

Influence of prolonged deprivation,age and culture on the development of future orientation

Prolonged deprivation and future orientation (FO) were studied in 200 Indian and Nepalese students of 14–16 and 18–20 years with verbal measures. In both cultures low deprived subjects were significantly more future-oriented. In the development of FO both age and deprivation were significant with experiential aspect of socialization exerting greater influence than physico-economic deprivation.     

Acoustic and semantic similarity effects on repetition avoidance in produced sequences

The question of whether repetition avoidance in sequential response production depends on the phonetic or the semantic encoding of previous responses was investigated by varying the acoustic and semantic similarity among the response alternatives. The results indicated that acoustic similarity affected repetition avoidance with six alternative words and a production rate of one per second, but not with four alternative letters and a rate of one per 2 sac. Semantic similarity between words was also studied, and was not seen to affect repetition avoidance. Results were explained by means of a model in which comparisons between a memory set of admissible responses and a memory set of recent responses are made at a phonetic level of response representation.     

The roles of self-regulation and partner regulation on romantic relationship quality

Research into self-regulation and partner regulation strategies has largely involved parallel lines of research, thus, it is difficult to determine the relative contribution of both forms of regulation when it comes to relationship outcomes. Therefore, the question remains as to which form of regulation is more strongly associated with relationship quality; is it more important to focus on adaptive self-regulation or adaptive strategies to regulate one's partner? The current research addresses this important gap by comparing the relative associations of adaptive self-regulation and adaptive partner regulation strategies on romantic relationship quality. A community sample of mixed gender couples (N = 114) who were predominantly satisfied with their current relationships – but nonetheless still experienced relationship conflict – were administered self-report assessments of various self-regulation and partner regulation strategies as well as a measure of relationship quality. Couples also participated in a videotaped discussion of an unresolved relationship issue that was scored by trained coders for verbal and nonverbal indicators of self-regulation and partner regulation strategies. Actor–partner interdependence modeling revealed that for both men and women, adaptive self-regulation strategies were positively associated with their own evaluations of relationship quality as well as their partner's relationship quality. In contrast, engaging in adaptive partner regulation strategies was not significantly associated with men's or women's own, or their partner's relationship quality. Findings highlight the importance of focusing on self-regulation in relationships, as it is these strategies, over partner regulation strategies, that have more positive implications for the relationship quality experienced by typically satisfied couples.