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Wolff MW  Wolff KA 《Adolescence》2002,37(148):705-716
Problematic and unhealthy personality characteristics have typically been the focus of researchers interested in the possible causes of substance use/abuse. Recent research has begun to identify differences between individuals based upon frequency of use, with indications that moderate users may have "healthier" characteristics than either abstainers or regular users. The present study was conducted in a rural setting and compared personality structure (based on the California Psychological Inventory) among three groups of college students: abstainers, experimenters, and regular users. The comparisons were conducted as a function of all illicit substance use (excluding alcohol) and for alcohol use only. Minimal support was obtained for the above hypothesis when comparing the three groups on illicit substance use. When comparing the three groups on alcohol use only, support for the theory was identified, with fewer differences found between the experimenters and the abstainers than between the experimenters and the regular users. It is suggested that rural use of psychoactive substances may be more limited to alcohol due to easier availability and less stigma. Data supporting the "healthier" personality structure of moderate users of alcohol would thus be more likely in rural settings even though such use would still be "risky" behavior given its illegality for individuals under age 21. The need for adaptations to current treatment approaches is suggested.  相似文献   
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This article reports on the feasibility of using interactive voice response (IVR) technology to obtain daily reports of attitudes toward alcohol and tobacco use among children 9–13 years of age. Two studies were conducted. The first was an investigation of the use of IVR technology to obtain daily data from a sample of primary school children over a period of 8 weeks. The second was an extension of the research to a large sample of primary and secondary school children in urban and rural areas who provided daily data over a 4-week period. Retention and compliance rates comparable to those obtained with adults were evident in both studies, supporting the feasibility of this technology with children. The results are discussed in relation to the benefits of this methodology for health research, particularly for studies of sensitive topics conducted with children and adolescents.  相似文献   
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Wolff P 《Cognition》2003,88(1):1-48
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This article reviews some of our recent functional magnetic resonance imaging (fMRI) studies of stuttering. Using event-related fMRI experiments, we investigated brain activation during speech production. Results of three studies comparing persons who stutter (PWS) and persons who do not stutter (PWNS) are outlined. Their findings point to a region in the right frontal operculum (RFO) that was consistently implicated in stuttering. During overt reading and before fluency shaping therapy, PWS showed higher and more distributed neuronal activation than PWNS. Immediately after therapy differential activations were even more distributed and left sided. They extended to frontal, temporal, and parietal regions, anterior cingulate, insula, and putamen. These over-activations were slightly reduced and again more right sided two years after therapy. Left frontal deactivations remained stable over two years of observation, and therefore possibly indicate a dysfunction. After therapy, we noted higher activations in persons who stutter moderately than in those who stutter severely. These activations might reflect patterns of compensation. We discuss why these findings suggest that fluency-inducing techniques might synchronize a disturbed signal transmission between auditory, speech motor planning, and motor areas.

Educational objectives: The reader will learn about and be able to: (1) identify regions of brain activations and deactivations specific for PWS; (2) describe brain activation changes induced by fluency shaping therapy; and (3) discuss the correlation between stuttering severity and brain activation.  相似文献   

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