Expectation and temperament moderate amygdala and dorsal anterior cingulate cortex responses to fear faces

A chronic tendency to avoid novelty is often the result of a temperamental bias called inhibited temperament, and is associated with increased risk for anxiety disorders. Neuroimaging studies have demonstrated that an inhibited temperament is associated with increased amygdalar blood-oxygenation-level-dependent (BOLD) response to unfamiliar faces that were not expected; however, the effects of variations in expectancy remain unknown. Using functional magnetic resonance imaging (fMRI), we studied BOLD response to infrequently encountered fear faces that were either expected or not expected in 42 adults with an inhibited or an uninhibited temperament. Individuals with an inhibited temperament had greater amygdala, but less dorsal anterior cingulate cortex (dACC), BOLD response when the stimuli were expected. In contrast, those with an uninhibited temperament had a smaller amygdala but larger dorsal anterior cingulate cortex BOLD response when expecting to see fear faces. These findings demonstrate temperament differences in expectancy effects and provide preliminary evidence for the dACC as a neural substrate mediating differences in inhibited temperament. Enhanced amygdala sensitivity coupled with weak inhibitory control from the dACC may form a neural circuit mediating behaviors characteristic of inhibited temperament and risk for anxiety disorders.     

A temporally dynamic context effect that disrupts voice onset time discrimination of rapidly successive stimuli

Across three experiments, voice onset time discrimination along a /ba/-/pa/ continuum was found to be influenced by the order of presentation of rapidly successive stimuli. Specifically, discrimination was disrupted when a relatively unambiguous /pa/ syllable was presented before, rather than after, a more ambiguous /pa/ or /ba/ syllable. In Experiments 1 and 2, for between-category discrimination, this order effect was significant at interstimulus intervals (ISIs) below 250 msec, but not at 250 or 1,000 msec. In Experiments 2 and 3, the order effect was also significant for within-category discrimination at ISIs below 250 msec. In addition, in Experiment 3 this order effect was not diminished by provision of performance feedback across eight testing sessions. These findings reveal a particular vulnerability of phonological processing in response to rapidly successive stimuli and may have implications for mathematical and neural models of speech processing of normal and impaired populations.     

Racial-Ethnic Differences in Genetic Amniocentesis Uptake

The objective of this study was to determine the role of health beliefs in genetic amniocentesis acceptance in a diverse racial-ethnic population. Participants completed a previously-validated questionnaire consisting of three sections: (1) demographics, (2) amniocentesis knowledge, and (3) health beliefs, which assessed perceived susceptibility, seriousness of potential impact, benefits of testing, and barriers to testing. The results showed that Hispanic women were less likely to accept amniocentesis (51.5% vs. Caucasian 82.8%, African American 82.9%, Asian 82.8%). Education level was the only demographic factor higher among acceptors. Women who accepted amniocentesis had higher perceived seriousness, susceptibility, and benefits HBM scores and higher knowledge scores than women who declined. HBM scores and knowledge predicted the amniocentesis decision correctly 91.5% of the time. Individual health beliefs and knowledge play a greater role in genetic amniocentesis acceptance than do demographic factors such as race-ethnicity.     

The accuracy of spatial information from temporally and spatially organized mental maps

The way a space is learned can result in a mental mapthat is either temporally or spatially organized (Curiel & Radvansky, 1998). The present study examined the availability of spatial information under maplearning conditions where either temporal or spatial organization has been previously observed. The finding was that people were fairly accurate in tasks that explicitly required the use of spatial information. However, there was a particular advantage for having a spatially organized mental mapin a direction judgment task, especially for short distances where fine-grained knowledge was required. In contrast, there was no clear advantage for either group in a distance estimation task. These data are interpreted in the context of Huttenlocher’s category adjustment model.     

Discrimination and Puerto Rican children's and adolescents' mental health

Two studies of Puerto Rican youths' development on the U.S. mainland examined the consequences of perceived racial/ethnic discrimination on mental health. In Study I, children were found to have a low likelihood of perceiving discrimination, whereas in Study 2, nearly half of the adolescent sample reported perceiving racial/ethnic discrimination. Although both groups scored high on multiple indicators of mental health, perceiving discrimination and worrying about discrimination were negatively associated with some dimensions of self-esteem and positively associated with depression and stress. Adolescents were aware of negative stereotypes about Puerto Ricans, and nearly half of them related discriminatory instances. Results suggest that both perceiving discrimination and anxiety regarding discrimination can serve as risk factors for the mental health of this population.     

Central galanin administration blocks consolidation of spatial learning

Galanin is a neuropeptide that inhibits the evoked release of several neurotransmitters, inhibits the activation of intracellular second messengers, and produces deficits in a variety of rodent learning and memory tasks. To evaluate the actions of galanin on encoding, consolidation, and storage/retrieval, galanin was acutely administered to Sprague-Dawley rats at time points before and after training trials in the Morris water maze. Intraventricular administration of galanin up to 3h after subjects had completed daily training trials in the Morris water task impaired performance on the probe trial, indicating that galanin-blocked consolidation. Pretreatment with an adenylate cyclase activator, forskolin, prevented the deficits in distal cue learning produced by galanin. Di-deoxyforskolin, an inactive analog of forskolin, had no effect. These results provide the first evidence that galanin interferes with long-term memory consolidation processes. A potential mechanism by which galanin produces this impairment may involve the inhibition of adenylate cyclase activity, leading to inhibition of downstream molecular events that are necessary for consolidation of long-term memory.     

Role of Sexual Orientation and Gender-Related Traits in Disordered Eating

This study was designed to examine the role of both sexual orientation and gender-related personality traits in disordered eating attitudes and behavior, including body dissatisfaction. Self-report measures assessing negative and positive gender traits,body dissatisfaction, drive for thinness, dietary restraint, and bulimic symptoms were administered to 266 participants (64 lesbians, 73 heterosexual women, 69 gay men, and 60 heterosexual men; 85% Anglo-Australian Caucasians, 15% Caucasians from Non-English-speaking backgrounds). Consistent with previous research, gay men scored significantly higher than heterosexual men on body dissatisfaction and dietary restraint, whereas lesbians scored significantly lower in comparison to the heterosexual women on body dissatisfaction, drive for thinness, dietary restraint, and bulimia. For men, the additional amount of variance accounted by the gender traits was significantly higher than that accounted for by sexual orientation. For the women, the gender traits also accounted for an additional significant amount of variance; however, overall the amount of variance accounted for by sexual orientation was greater. However, for both men and women, irrespective of their sexual orientation, it was higher scores on negative femininity that predicted higher levels of disordered eating. These results are consistent with previous studies that have found support for the femininity hypothesis in disordered eating.     

Intent and Choice Regarding Maternal Employment Following Childbirth

This study examined the impact of personal values, perceived spouse preference, and family income on maternal employment intent and maternal employment following childbirth. This study followed a sample of 70 expectant working mothers from the last trimester of pregnancy to 6 months following childbirth. Traditional gender role values and perceived spouse preference influenced maternal employment intent measured prior to childbirth. Maternal employment intent and marital partner's income influenced maternal employment 6 months after childbirth. The results of this study provided support for Brown's (1996) value-based theory of career choice. Results also suggested that some women who preferred to be withdrawn from the labor force had to work to provide greater family income.     

Anger-Related Traits and Response to Interpersonal Conflict Among New York City Traffic Agents1

This study evaluates the psychosocial correlates of anger-related traits. Participants include New York City traffic enforcement agents (TEAs), who issue summonses for vehicular and parking violations and are frequently confronted by angry motorists. This sample of TEAs is 53% African American and 57% female. Participants completed surveys at 2 points, 4 months apart, which measured attitudinal, affective, and expressive components of hostility and anger, as well as dimensions of workplace psychosocial response. Results indicate that trait anger-in was positively associated with frequency of conflict, anger intensity, and burnout in cross-sectional analyses; and positively associated with frequency of conflict in prospective analyses. Trait anger was positively associated with an increase in burnout over a 4-month period. These findings provide support for the transactional model of hostility and health and have implications for worksite interventions promoting cardiovascular health.