The Effect of Stress on Spontaneous Nest Leaving Behavior in the Mouse: An Improved Model of Stress-Induced Behavioral Pathology

The present experiments were conducted to develop a more sensitive and reliable model of stress-induced behavioral pathology in the mouse. Male mice were housed singly in nest cages connected to either a circular tunnel, a recreational cage or a large box with food foraging apparatus. Spontaneous nocturnal out of nest activity or food foraging behavior in these environments was continuously monitored for a two week period during which time the effects of stress were examined. It was found that both repeated restraint and aggression stress markedly and persistently reduced out of nest nocturnal activity or food foraging behavior in all 3 environments but did not alter activity in a novel open field or plus maze or food or saccharin intake in the nest cage. In a preliminary experiment the reduction in out of nest activity by stress was attenuated by prior chronic treatment with the antidepressant, desmethylimipramine. Plasma corticosterone was elevated immediately after aggression stress but reduced 5 hr after chronic aggression stress. The reduction in activity did not appear the result of increased anxiety as measured by spontaneous risk assessment behavior in the nest. It is concluded that the decrease in out of nest activity after stress in the present studies models a withdrawn behavioral state and may be due to either or both a decrease in appetitive motivation to leave the nest or an increased aversion to the external environment which does not apparently involve anxiety.     

What Is Social about Justice? Inclusive Identity and Group Values as the Basis of the Justice Motive

Three studies tested the claim that the justice motive is based on commitment to the perceived values of the “primary category” of potential recipients of an allocation. In Study 1, participants who identified more strongly with their group regarded a member who represented the group's strengths as more entitled to a common profit. In Study 2, participants judged their own entitlement versus that of a member who represented the group's strengths. Members who identified more strongly with their group were less likely to display self-interest in their judgments. In Study 3, participants judged the entitlement of an in-group member representing out-group strengths versus an out-group member representing in-group strengths. When identification with the primary category (including in-group and out-group) was strong, members who identified more strongly with their in-group viewed the out-group member representing in-group values as more deserving.     

Depth of processing and recall of threat material in fearful and nonfearful individuals

Although many studies have examined the nature of memory distortions in anxious individuals, few have considered biases in specific memory processes, such as encoding or retrieval. To investigate whether the presentation of threat material facilitates encoding biases, spider fearful (n=63), blood fearful (n=73), and nonfearful (n=75) participants encoded spider related, blood related, and neutral words as a function of three levels of processing (i.e., structural, semantic, and self referent). Participants subsequently completed either a free recall or a recognition task. All participants demonstrated a partial depth of processing effect, such that they recalled more words encoded in the self referent condition than in the other two conditions, but groups did not differ in their recall of stimuli as a function of word type. Relative to participants in the other groups, spider fearful participants had fewer spider related intrusions in the recall condition, and they made fewer errors in responding to structural and semantic encoding questions when spider related words were presented. These results contribute to an increasingly large body of literature suggesting that anxious individuals are not characterized by a memory bias toward threat, and they raise the possibility that individuals with spider fears process threat-relevant information differently than individuals with blood fears.     

Adaptive modes of rumination: the role of subjective anger

Rumination has been demonstrated to have negative consequences on affect, behaviour, and physiological markers. Recent studies, however, suggest that distinct “modes” of anger-associated rumination may lead to several positive consequences. Previous research primarily used recall procedures of anger episodes to elicit anger. By contrast, the present study focused on the effect of subjective anger on the process of rumination and tested its effects in a “staged” social interaction where a confederate provoked participants. Subsequently, participants engaged in rumination about the anger-eliciting event either in an abstract-distanced or a concrete-immersed rumination mode. Results showed an adaptive effect of abstract-distanced rumination on subjective anger primarily if anger is high prior to rumination. The findings also suggest different self-reported anger-related coping strategies in response to subjective anger intensity. These findings highlight that an abstract-distanced rumination may have differential effects on affective outcomes and anger-related coping strategies.     

Autobiographical memories of anxiety-related experiences

Ninety-nine undergraduate students retrieved three memories associated with each of the five emotional experiences: panic, trauma, worry, social anxiety, and feeling content. Subsequently, they answered 24 questions assessing properties of each memory, including the vividness and perceived accuracy of the memories and sensory, emotional, and anxiety-related experiences during retrieval. Memories were coded for affective tone and specificity. Results indicated that panic-related and trauma-related memories were rated similarly as content memories, but that they generally were associated with more imagery and emotional experiencing than worry-related or social anxiety-related memories. Participants experienced panic and worry symptoms to the greatest degree when they retrieved panic-related and trauma-related memories. All anxiety-related memories were characterized by more negative tone than content memories. Panic-related and trauma-related memories were more specific than worry-related, social anxiety-related, and content memories. These findings can explain partially why individuals with some, but not all, anxiety disorders experience enhanced memory for threatening material.     

Dysfunctional beliefs in panic disorder: The Panic Belief Inventory

The Panic Belief Inventory (PBI) was developed to assess beliefs that increase the likelihood of catastrophic reactions to physical and emotional experiences in panic disorder. In the first stage of scale development, 197 panic disorder patients completed the PBI and standard self-report inventories of psychiatric symptomatology. An exploratory factor analysis yielded a 4-factor solution from which a 35-item instrument with 4 scales was constructed. The shortened measure and its scales had good internal consistency and convergent validity and moderate discriminant validity. Subsequently, 22 panic disorder patients who received cognitive therapy completed the PBI and other self-report inventories of dysfunctional cognitions at intake, 4 weeks, 8 weeks, termination, and several follow-up intervals. Results indicated that the PBI decreased significantly across treatment, with the largest decline occurring between intake and 4 weeks into treatment. The PBI correlated more strongly with dysfunctional cognitions associated with anxiety than dysfunctional cognitions associated with depression. These results provide preliminary evidence that the PBI has adequate psychometric characteristics, is useful to assess change in dysfunctional beliefs during treatment, and has the potential to advance cognitive theories of panic.     

Nicht motorische Symptome bei Morbus Parkinson

Nonmotor symptoms in Parkinson?s disease have a high impact on quality of life. A broad range of symptoms can be found in all stages of the disease, including gastrointestinal symptoms,bladder problems, erectile dysfunction, orthostatic hypotension, sleep disturbances, depression, dementia, psychosis, and drug-induced behavioral changes. The guidelines of the Austrian Parkinson’s Disease Society and a recent review of the Movement Disorder Society provide therapy recommendations according to evidence-based data.     

Nicht motorische Symptome bei Morbus Parkinson (Teil II)

Nonmotor symptoms in Parkinson’s disease have a high relevance for quality of life. A broad range of symptoms can be found in all stages of the disease, including gastrointestinal symptoms, bladder problems, erectile dysfunction, orthostatic hypotension, sleep disturbances, depression, dementia, psychosis, and drug-induced behavioral changes. The guidelines of the Austrian PD society and a recent review of the Movement Disorder Society provide therapy recommendations according to evidence-based data.