Self-Reported Questionnaire Detects Family History of Cancer in a Pancreatic Cancer Screening Program

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer death; approximately 5–10% of PDAC is hereditary. Self-administered health history questionnaires (HHQs) may provide a low-cost method to detail family history (FH) of malignancy. Pancreas Center patients were asked to enroll in a registry; 149 with PDAC completed a HHQ which included FH data. Patients with FH of PDAC, or concern for inherited PDAC syndrome, were separately evaluated in a Prevention Program and additionally met with a genetic counselor (GC) to assess PDAC risk (n?=?61). FH obtained through GC and HHQ were compared using Wilcoxon signed-rank sum and generalized linear mixed models with Poisson distribution. Agreement between GC and HHQ risk-assessment was assessed using kappa (κ) statistic. In the Prevention Program, HHQ was as precise in detecting FH of cancer as the GC (all p?>?0.05). GC and HHQ demonstrated substantial agreement in risk-stratification of the Prevention Program cohort (κ?=?0.73, 95% CI 0.59–0.87.) The sensitivity of the HHQ to detect a patient at elevated risk (i.e., moderate- or high-risk) of PDAC, compared to GC, was 82.9% (95% CI 67.3–92.3%) with a specificity of 95% (95% CI 73.1–99.7%). However, seven patients who were classified as average-risk by the HHQ were found to be at an elevated-risk of PDAC by the GC. In the PDAC cohort, 30/149 (20.1%) reported at least one first-degree relative (FDR) with PDAC. The limited sensitivity of the HHQ to detect patients at elevated risk of PDAC in the Prevention Program cohort suggests that a GC adds value in risk-assessment in this population. The HHQ may offer an opportunity to identify high-risk patients in a PDAC population.     

The diagnostic and therapeutic uses of family conflicts in a Chinese context: the case of anorexia nervosa

There are two untested cultural beliefs commonly held among family therapists in Hong Kong: (1) Chinese families are reserved in disclosing their conflicts to an 'outsider'; and (2) it would be culturally inappropriate to elicit family conflicts in treatment. In this article, an attempt is made to examine these cultural beliefs based on the results of a qualitative study of thirty-five Chinese patients suffering from anorexia nervosa. These patients and their families have participated in a pre-treatment family interview prior to the commencement of family treatment. The results of the study have shown that the afflicted Chinese families are very willing to disclose their difficulties to the researcher. The onset of the disorder has led to different types of family conflicts including: (1) overt family conflicts related to food refusal; (2) covert family conflicts; (3) increased sibling rivalry; (4) increased parent–child conflict; and (5) marital tension and distress. The clinical implications of this study are discussed at the end of the article.     

《论语》:一种可能的情感解读

在面对三代经礼文化日益衰颓的社会情势时,孔子开始向人之内在情感领域发掘道德实践的理据。这种发掘,一方面使他实现了对传统礼乐的改造,一方面则凿通了经由内在真实情感的抉发而走向儒家性情论伦理思想的义理道路。这种人本主义的情感关怀和情感诉求,渗透于孔子诠释道德要目与道德行为、论《诗》、论乐的诸多言论之中。因此,可以毫不夸张地说,《论语》是一部未言“情”字(“情感”义)而又处处关“情”的著作。     

对感觉记忆在相同范畴视觉搜索中作用的研究

该文以三种字母卡片为刺激物,通过两种靶字母搜索实验,探讨了感觉记忆在相同范畴视觉搜索中的作用。实验结果显示,感觉记忆和短时记忆信息都可能利用时的搜索成绩,明显高于限用短时记忆信息时的搜索成绩。这表明,感觉记忆信息可以直接用于相同范畴的视觉搜索。     

差异与互补:皮亚杰与维果茨基认知发展观比较的新思考

皮亚杰与维果茨基是10世纪两位最有影响的发展心理学家．他们开辟了研究儿童发展的两条线路。这两种取向存在着根本性的差异,同时在研究方法与具体观点中又存在着多方面的类似和交叉．两种取向互动互补．共同描绘了儿童发展的整体画卷。     

自我同一性危机与道德选择多元化

自我是一个复杂的概念 ,自我同一性则是依赖于我们经历过的所有不同的自己的综合 ,是对自身发展的一种强烈的一致性和连续性的主观感觉。自我同一性危机是指自我处于自身的矛盾与冲突中 ,反映了自我在过去和现在、彼地和此地的不连续。在现代社会 ,随着个体道德选择的可能性与主动性的增强 ,自我的完善与否对道德选择相应产生了积极与消极的作用。     

Death anxiety and sexual risk-taking: different manifestations of the process of defense

College students(n = 162) completed measures of death anxiety and sexual risk-taking, with a thought listing procedure in-between. Those who completed the death anxiety measure first (Death Salient condition) reportedgreater willingness to engage in high-risk sexual behavior than the Non-Death Salient group. This result was consistent with the hypothesis that evoking death anxiety would produce denial-based defensive activity. Also, Death Salient participants reporting more death thoughts were lower on risk-taking, as predicted. Interestingly, Death Salient participants reporting stressful thoughts about issues unrelated to personal mortality (displacement) were also less willing to engage in high-risk sexual behavior. The results are discussed in relation to a new, avowal-based model of the process of psychological defense.     

虚拟团队中的信任研究

信任是从组织行为学领域研究虚拟团队的一个重要课题。与传统组织中的信任相比,虚拟团队中的信任主要是认知或行为定向的;它在最初几次互动的基础上迅速建立起来,并通过随后的沟通行为维持下去,所以沟通行为和沟通内容的特征对虚拟团队中信任的建立和维持有着特殊重要的意义。由于目前研究方法所限,无法确定虚拟团队中信任与绩效的因果关系,但是它们之间存在着密切的相关关系。     

Repetition priming within and between languages in semantic classification of concrete and abstract words

Although concrete nouns are generally agreed to have shared core conceptual representations across languages in bilinguals, it has been proposed that abstract nouns have separate representations or share fewer semantic components. Conceptual repetition priming methodology was used to evaluate whether translation equivalents of abstract nouns have shared conceptual representations and compare the degree of conceptual overlap for concrete and abstract nouns. Here 72 Spanish-English bilinguals made concrete-abstract decisions on English and Spanish nouns. Both concrete and abstract nouns elicited substantial between-language priming and these effects were of equivalent size, indicating that translation equivalents of both concrete and abstract nouns have shared conceptual representations and that abstract words do not share fewer components. The between-language priming effects and their attenuation relative to within-language priming indicate that the within-language effect is based on facilitation of both word comprehension and semantic decision processes.     

《古兰经》汉译活动与伊斯兰教本土化

伊斯兰教本土化是中外文化交流的成功范例。本文通过对伊斯兰教经典《古兰经》汉译的分析,述说了中外文化交流的历史经验,说明了异域、异质文化交流会通、融为一体的必要条件、途径、意义等。着重强调文化之间的交流只有在本土文化的"母土"和"土壤"中找到生长点,才能最终被接受、融合,成为本土文化的新的营养和有机成分。