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Deschaux O Motanis H Spennato G Moreau JL Garcia R 《Neurobiology of learning and memory》2011,95(4):510-518
Post-extinction exposure of rats to a sub-conditioning procedure can evoke conditioned fear, which may correspond to fear return and/or fear learning potentiation. The aim of the present study was to clarify this issue and examine the effects of tetanic stimulation of the hippocampus (HPC) and medial prefrontal cortex (mPFC), two brain regions implicated in post-extinction modulation of conditioned fear. Rats were initially submitted to five tone-shock pairings with either a 0.7-mA or 0.1-mA shock. Tone-evoked freezing was observed only with the higher shock intensity, indicating that the 0.1-mA shock corresponded to a sub-conditioning procedure. All conditioned rats underwent fear extinction with 20 tone-alone trials. When retrained with the sub-conditioning procedure, they displayed again tone-evoked freezing, except when the initial tone was unpaired or a new tone was paired with the 0.1-mA shock, demonstrating fear return rather than fear learning potentiation. We also found that HPC and mPFC tetanic stimulations, applied 24h after the sub-conditioning procedure, similarly reduced this fear return. However, mPFC inactivation abolished temporary HPC tetanus effect, whereas HPC inactivation did not interfere with mPFC tetanus effect. These data confirm our previous findings and reveal the nature of HPC-mPFC interactions in post-extinction modulation of conditioned fear. 相似文献
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研究学科领域知识丰富性不同的学生在问题表征过程中信息表征层次的特点。采用“学习-再认”范式,以5类等式为材料,62名初二学生参与实验。结果:两组被试对表面和原理特征一致的等式产生明显的错误再认;对表面特征不一致等式的错误率明显减少。无论原理特征是否一致,两组对表面特征一致等式的反应时无显著差别,但在正确率上丰富组的更高。说明,两组均以有序的系列加工方式编码信息,优先编码表面特征。贫乏组对原理特征的编码干扰表面特征的加工,因而原理特征被丢弃。丰富组加工表面特征则无干扰现象出现,两种特征均能作为再认线索。 相似文献
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通过整群抽样的方法抽取了1404名中学生,对其施测核心自我评价量表,我的班级问卷和抑郁问卷,应用无约束结构方程模型技术和结构方程中介效应检验技术,分别考察了核心自我评价在班级环境与抑郁关系间的调节与中介作用。结果表明:(1)核心自我评价对班级环境中的师生关系、同学关系、竞争三者和抑郁之间的关系起着调节作用,但结构模型的拟合指数不佳;(2)核心自我评价在班级环境与青少年抑郁间起着中介作用,其中核心自我评价在竞争与抑郁间关系起着完全中介作用。 相似文献
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本文通过对426名在职人员的调查,探讨了变革型领导对工作绩效与满意度的影响机制。最后采用SPSS 13.0和Lisrel 8.7 对数据进行多层级线性回归分析,并依据温忠麟等(2006)的统计步骤分析了有中介的调节作用,得到如下结果:(1)在控制了年龄、性别与任职年限之后,自我效能在变革型领导与工作绩效、工作满意度之间都起部分中介作用;(2)核心工作特征在变革型领导与工作绩效之间起调节作用,调节作用需要通过自我效能作为中介变量。文章最后讨论了本研究的理论和实践意义。 相似文献
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The present study examined the effects of orthographic neighborhood (N) size on the cognitive processes underlying Chinese character reading. Previous research has shown increasing N size facilitates word naming and recognition performance in alphabetic languages. Experiment 1 revealed that a large N size was associated with a general inhibition of processes underlying character reading, in contrast to previous findings with alphabetic languages. This inhibitory effect was influenced by regularity and consistency. Experiment 2 sought to assess the effects of higher-frequency neighbors on character naming performance. The results revealed that higher-frequency neighbors with different pronunciation to the target interfered with the phonological retrieval of targets. We propose that this type of interference may have caused the N size effect observed in Experiment 1. The results of Experiment 3 revealed that a large N size facilitated target naming in the absence of higher-frequency neighbors. The current results shed light on the processes underlying character naming, and we propose possible cognitive mechanisms of the N size effect on Chinese character naming. 相似文献
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Jiin‐Huarng Guo Hubert J. Chen Wei‐Ming Luh 《The British journal of mathematical and statistical psychology》2011,64(3):439-461
The allocation of sufficient participants into different experimental groups for various research purposes under given constraints is an important practical problem faced by researchers. We address the problem of sample size determination between two independent groups for unequal and/or unknown variances when both the power and the differential cost are taken into consideration. We apply the well‐known Welch approximate test to derive various sample size allocation ratios by minimizing the total cost or, equivalently, maximizing the statistical power. Two types of hypotheses including superiority/non‐inferiority and equivalence of two means are each considered in the process of sample size planning. A simulation study is carried out and the proposed method is validated in terms of Type I error rate and statistical power. As a result, the simulation study reveals that the proposed sample size formulas are very satisfactory under various variances and sample size allocation ratios. Finally, a flowchart, tables, and figures of several sample size allocations are presented for practical reference. 相似文献