发展性阅读障碍者的快速命名缺陷

快速命名任务是一种需要命名多个高熟悉项目的认知任务,尤其适合用来对成因复杂的发展性阅读障碍进行研究。许多研究者使用不同类型的快速命名任务发现,发展性阅读障碍者的快速命名缺陷在眼动过程表现为中央凹和副中央凹的加工困难,在认知过程中表现为抑制能力较差等。未来的研究中应该注意到快速命名缺陷的复杂性,采用多种方法相结合的方式来探究快速命名缺陷的本质,从而建立系统性的假说。     

Calcium signaling in mitral cell dendrites of olfactory bulbs of neonatal rats and mice during olfactory nerve Stimulation and beta-adrenoceptor activation

Synapses formed by the olfactory nerve (ON) provide the source of excitatory synaptic input onto mitral cells (MC) in the olfactory bulb. These synapses, which relay odor-specific inputs, are confined to the distally tufted single primary dendrites of MCs, the first stage of central olfactory processing. beta-adrenergic modulation of electrical and chemical signaling at these synapses may be involved in early odor preference learning. To investigate this possibility, we combined electrophysiological recordings with calcium imaging in olfactory bulb slices prepared from neonatal rats and mice. Activation of ON-MC synapses induced postsynaptic potentials, which were associated with large postsynaptic calcium transients. Neither electrical nor calcium responses were affected by beta-adrenergic agonists or antagonist. Immunocytochemical analysis of MCs and their tufted dendrites revealed clear immunoreactivity with antibodies against alpha1A (Cav2.1, P/Q-type) and alpha1B (Cav2.2, N-type), but not against alpha1C (Cav1.2, L-type) or alpha1D (Cav1.3, L-type) calcium channel subunits. Moreover, nimodipine, a blocker of L-type calcium channels, had no effect on either electrical or calcium signaling at ON-MC synapses. In contrast to previous evidence, we concluded that in neonatal rats and mice (P5-P8), mitral cells do not express significant amounts of L-type calcium channels, the calcium channel type that is often targeted by beta-adrenergic modulation. The absence of beta-adrenergic modulation on either electrical or calcium signaling at ON-MC synapses of neonatal rats and mice excludes the involvement of this mechanism in early odor preference learning.     

The emergence of cultural self-constructs: autobiographical memory and self-description in European American and Chinese children

This study examined the emergence of cultural self-constructs as reflected in children's remembered and conceptual aspects of the self. European American and Chinese children in preschool through 2nd grade participated (N=180). Children each recounted 4 autobiographical events and described themselves in response to open-ended questions. American children often provided elaborate and detailed memories focusing on their own roles, preferences, and feelings; they also frequently described themselves in terms of personal attributes, abstract dispositions, and inner traits in a positive light. Chinese children provided relatively skeletal accounts of past experiences that centered on social interactions and daily routines, and they often described themselves in terms of social roles, context-specific characteristics, and oven behaviors in a neutral or modest tone. Findings are discussed in light of the self as a constructed meaning system of culture that emerges early in life.     

Psychosocial factors associated with adolescent boys' reports of dating violence

The prevalence of dating violence, as well as its association with psychosocial factors, was examined among a nationally representative sample of 9th- through 12th-grade U.S. boys (N = 7,434) who completed the 1999 Youth Risk Behavior Survey. The dependent variable was physical dating violence; the independent variables were violence, suicide, substance use, and sexual risk behavior. Unadjusted odds ratios (OR) and 95% confidence intervals (CI) were examined. Multivariate logistic regression was used to examine all significant independent variables from the univariate models. Adjusted OR and 95% CI were examined to assess the significance of these relationships. In terms of prevalence, 9.13% of the boys reported physical dating violence. Boys who reported sad/hopeless feelings (OR = 1.68), had attempted suicide (OR = 2.22), reported fighting (OR = 1.81), had multiple sex partners (OR = 3.53), and reported nonuse of condoms (OR = 1.66) were more likely to report physical dating violence. These findings indicate that physical dating violence among adolescent boys may be a more serious problem than has previously been recognized. It was concluded that intervention programs should include a focus on boys as not only perpetrators but also recipients of dating violence.     

Risk profiles of adolescent girls who were victims of dating violence

The prevalence of dating violence, as well as its relationship to potential risk factors, was examined among a nationally representative sample of 9th-through 12th-grade U.S. females (N = 7,824) who completed the 1999 Youth Risk Behavior Survey. The dependent variable was physical dating violence; the independent variables were violence, suicide, substance use, and sexual risk behavior. Unadjusted odds ratios (OR) and 95% confidence intervals were examined, and multivariate logistic regression analysis was conducted to identify the most significant risk factors. It was found that nearly one in ten of the adolescent girls reported dating violence. Twelfth-grade girls had the highest prevalence of dating violence. Girls who were victims of dating violence were more likely to be involved in other violent behaviors, to report extreme sadness and suicidal actions, to use illicit substances, and to engage in risky sexual behavior. Multivariate analysis revealed that dating violence was associated with sad/hopeless feelings (OR = 2.13), binge drinking (OR = 1.96), cocaine or inhalant use (OR = 2.90), multiple sex partners (OR = 2.38), nonuse of condoms (OR = 1.53), and ethnicity, specifically being Black (OR = 2.32) or Hispanic (OR = 1.82). These findings provide further evidence that there is a clustering of risk factors among certain adolescents, specifically girls who experience dating violence.     

Do we feel the same level of guilt about the wrongdoings of close ones and distant ones? The mediating role of behavioural control

Understanding whether and why individuals' emotional responses are different to the same behaviour performed by different others is important for understanding phenomena in social interaction. Given that there is no relevant research in Eastern culture testing such issues, the present research including two studies was conducted with Chinese samples and investigated whether Easterners experience more vicarious guilt about close ones' immoral behaviours than distant ones' immoral behaviours and the underlying mechanism of the effect. Study 1 showed that people felt more guilty when recalling close ones' misdeeds than distant ones' misdeeds. Study 2 replicated the findings of Study 1 using the scenario method and demonstrated that behavioural control partially mediated the effect of relationship closeness on vicarious guilt, that is, people reported more behavioural control over close ones' immoral behaviours, which in turn resulted in more vicarious guilt. Implications for social interaction and directions for future research are discussed.     

Brief Exposure to Misinformation Can Lead to Long‐Term False Memories

Do false memories last? And do they last as long as true ones? This study investigated whether experimentally created false memories would persist for an extended period (one and a half years). A large number of subjects (N = 342) participated in a standard three‐stage misinformation procedure (saw the event slides, read the narrations with misinformation, and then took the memory tests). The initial tests showed that misinformation led to a significant amount of false memory. One and a half years later, the participants were tested again. About half of the misinformation false memory persisted, which was the same rate as for true memory. These results strongly suggest that brief exposure to misinformation can lead to long‐term false memory and that the strength of memory trace was similar for true and false memories. Copyright © 2011 John Wiley & Sons, Ltd.     

资本主义经济关系中的政治、哲学与伦理——以MEGA2中马克思文本为基础的阅读与理解

<正>政治学与经济学的结合并非始于马克思;19世纪初,随着资本主义经济的迅速发展,在英国和欧洲大陆产生了相当一批政治经济学家,他们尝试从原则①上去理解、认识和论证资本主义经济关系的产生、存在和发展。19世纪40年代中期,马克思的批判思路由哲学、法学、社会学逐渐转向政治经济学。这一方面是其自身思想发展的逻辑性结果:对异化劳动关系的实证性论证,只能从政治经济     

并发症内涵刍议

并发症概念的不明确,使得临床及司法实践中出现诸多问题,如部分医务人员注意力降低、医患矛盾升级,对医疗损害鉴定及判决产生了不利影响.应从疾病诊断和诊疗操作两方面理解并发症的内涵,明确并发症并不一定是医院的免责事由,并规范对这一概念的使用.     

从“王贝事件”看医学学会组织的职能

2010年发生于武汉的超女王贝整容致死事件,使中国的医疗整形美容行业受到质疑.相关医学学会组织的职能缺失是事件引起社会关注的重要原因之一.通过梳理该事件发生发展的全过程,分析医学学会的作用,借以指出医学学会在制度建设和职业精神建设等方面存在的问题,并提出完善医学学会职能的建议.