The effects of testosterone on cognition in elderly men: a review

In this article, the literature examining the relationship between testosterone and various cognitive domains in elderly men is reviewed. The review focuses on the role of endogenous testosterone levels and the effects of androgen depletion and replacement. The cognitive domains most commonly linked to testosterone include memory and visuospatial function. Indeed, the literature suggests that in certain conditions (ie, hypogonadism, cognitive impairment) testosterone levels may be significantly associated with memory and visuospatial function, but not other cognitive functions. Studies with larger sample sizes and more sensitive cognitive measures are indicated, as questions remain about the potential role of testosterone as a cognitive enhancer.     

医护人员人文素质缺乏的管理责任及干预策略

医护人员人文素质缺乏与医学教育缺陷、人文管理意识不强、后续人文素质培养不利及执业环境恶化等综合因素密切相关。卫生行政主管部门和医院管理者首先应当确立人文管理理念,营造医院的人文氛围,承担起促进医学教育体制改革、加强岗位培训和着力培养社会需要的“人文科学型”医护人员的责任。     

微创医学中的介入性超声

超声检查具有实时、动态、灵活、方便等优点,在临床上有重要作用。介入性超声是在超声显像的基础上,为进一步满足临床诊断和治疗的需要而发展起来的一门新技术,在微创医学体系中占有非常重要的地位,但只有与其它微创技术联合应用才更有活力和生机。     

Cross-validation of the Mood Disorders Questionnaire, the Internal State Scale, and the Hypomanic Personality Scale

Previous research indicates that the Mood Disorder Questionnaire (MDQ), the Internal State Scale (ISS), and the Hypomanic Personality Scale (HPS) have the capacity to assess symptoms of bipolar spectrum disorders. The present study cross-validates these scales in a sample of 167 undergraduate students. Individuals were divided into high, medium and low likelihood of caseness (HLC, MLC and LLC) groups based on operationalised cut-off criteria on the MDQ. Scores on the ISS Perceived Conflict subscales were positively and proportionately associated with elevated likelihood of caseness. The HLC group was distinguished from the other two groups by high levels of ISS Depression, whereas the LLC group was distinguished from the other two groups by low levels of ISS Activation and hypomanic personality traits. The majority of individuals reported a history of isolated (hypo)manic experiences, and a quarter of the sample reached screening criteria for a bipolar spectrum disorder (Isometsae et al., 2003). The results are discussed in the context of the role of activation, depression, and interpersonal conflict in bipolar spectrum disorders.     

The visual discrimination of bending

The sensitivity of observers to nonrigid bending was evaluated in two experiments. In both experiments, observers were required to discriminate on any given trial which of two bending rods was more elastic. In experiment 1, both rods bent within the same oriented plane, and bent either in a frontoparallel plane or bent in depth. In experiment 2, the two rods within any given trial bent in different, randomly chosen orientations in depth. The results of both experiments revealed that human observers are sensitive to, and can reliably detect, relatively small differences in bending (the average Weber fraction across experiments 1 and 2 was 9.0%). The performance of the human observers was compared to that of models that based their elasticity judgments upon either static projected curvature or mean and maximal projected speed. Despite the fact that all of the observers reported compelling 3-D perceptions of bending in depth, their judgments were both qualitatively and quantitatively consistent with the performance of the models. This similarity suggests that relatively straightforward information about the elasticity of simple bending objects is available in projected retinal images.     

早产儿预防性应用抗生素的临床决策思路

近年来,随着对滥用抗生素所引起的细菌耐药性和二重感染的认识的逐步深入,预防性应用抗生素在临床上越来越受到限制。但由于早产儿感染的临床隐匿性和易并发严重并发症等特点,预防早产儿感染的发生和进一步的发展,就显得尤为重要。通过对早产儿发生感染的易感因素、感染诱因和临床特点的分析研究,来探讨早产儿临床预防应用抗生素的必要性、合理性及临床决策思路。     

制造行业管理胜任力与绩效关系的实证研究

通过对571名制造型企业管理者的问卷调查,探索并验证了制造业管理胜任力结构维度,检验了不同背景因素对管理胜任力的影响。结果表明:制造业管理胜任力具有六维结构,包含22个指标,其信度和效度较好;不同管理层次的管理者在制造过程控制和市场营销策划维度上的评价有显著性差异,不同企业规模下的管理者在行业核心理念和产品系统管理维度上的评价有显著性差异;产品系统管理与市场营销策划能力对制造业管理者绩效有良好的预测力。同时发现,制造业管理胜任力不能较好地解释周边绩效的变异量。     

Relationship between psychopathy and indirect aggression use in a noncriminal population

Psychopathy has long been associated with increased use of direct aggression and violence, especially among male inmates. Little research has, of yet, considered the relation between psychopathy and indirect forms of aggression. The current research sought to investigate the relationship between psychopathy and indirect aggression in a noncriminal sample. The results indicated that there was a strong relationship between psychopathic traits and indirect aggression, with strong correlations between indirect aggression and both factor 1 (coldheartedness) and factor 3 (impulsive antisociality). This association remained significant even after the effects of direct aggression had been controlled for. Path analysis indicated that both direct and indirect aggression was underpinned by the same psychopathy factors. This suggests that high psychopathy scorers will utilize direct and indirect aggression equally and, as such, the choice of one type of aggression over the other may be dependant on either situational factors or external moderators. Aggr. Behav. 35:408–421, 2009. © 2009 Wiley‐Liss, Inc.     

童年中期身体侵害、关系侵害与儿童的情绪适应

采用整群抽样法选取2603名小学儿童（平均年龄9.05 ± 0.53岁）作为被试,考察童年中期同伴侵害现象的基本特点,以及同伴侵害与情绪适应（孤独感、社交焦虑和抑郁）的关系。结果发现：（1）在性别差异方面,男生的身体侵害与关系侵害水平均显著高于女生,与身体侵害相比,关系侵害的性别差异程度较小。在同伴侵害的类型特点方面,儿童遭受身体侵害的水平显著高于关系侵害。（2）身体侵害、关系侵害与儿童的各情绪适应指标显著正相关,身体侵害和关系侵害能同时预测儿童的情绪适应不良;并且与身体侵害相比,关系侵害对情绪适应的影响更大。（3）身体侵害与社交焦虑的关系表现出性别差异,即身体侵害能预测女生的社交焦虑,而对男生的社交焦虑不存在预测作用;但同伴侵害与孤独感、抑郁的关系不受性别的调节。总体而言,有同伴侵害经历的男生和女生具有相似的情绪适应问题。