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141.
采用事件相关电位技术(ERP),通过简单赌博任务,操纵结果预期的效价(输或赢)与风险(高风险与低风险),考察了个体对结果预期阶段的效价和风险评估的脑内时程动态加工过程。脑电结果发现:(1)在N2成分上,结果预期的效价主效应显著,预期输比预期赢能够引起更大的N2波幅;结果预期的风险主效应不显著。(2)在N500成分上,效价与风险之间的交互作用边缘显著,进一步简单效应分析发现,在预期输的条件下,肯定会输的N500波幅显著大于可能会输;而在预期赢的条件下,肯定会赢与可能会赢之间的N500波幅差异不显著。这说明,在不确定决策过程中的结果预期阶段,个体可能先对结果预期的效价进行加工,然后再对风险进行评估。 相似文献
142.
论马克思主义的整体性(上) 总被引:1,自引:0,他引:1
近年来,随着 "马克思主义理论"被正式确立为国家一级学科,"马克思主义学院"在全国高等院校纷纷成立,国内马克思主义研究在表面上也呈现出一派热闹非凡的景象。于是马克思主义的整体性问题被提了出来。然而,与这种表面上热闹的景象形成鲜明对照的是,真正从心灵深处认同、信仰马克思主义的人并不很多。这种悖论式的现象不能不引起我们足够的重视。对于研究马克思主义的理论工作者而言,必须对眼前令人眼花缭乱的马克思主义 "热"进行 "冷"思考,就是说,必须认真地、郑重地提出并弄清这样一个问题: 马克思主义就其本义而言,是站在大众立场、为大众立言、为 相似文献
143.
为了考察高职生因果定向的特点及因果定向与学生学业表现(学业成绩和专业技能)的关系。该研究以修订的一般因果定向量表为工具,在济南和淄博的三所高职抽取505名学生作为被试进行调查。结果发现:1)修订后的一般因果定向量表具有良好的信效度;2)高职生在因果定向的三个维度上得分差异显著,由高到低依次为自主定向、控制定向和非个人定向;3)自主定向显著正向预测学业表现,控制定向显著负向预测学业表现,而非个人定向对学业表现的预测作用不显著。我国高职生与国外被试的因果定向特点基本一致,说明因果定向具有一定的文化普适性。同时,不同因果定向对学业表现具有不同的预测作用,教育者有必要对学生进行因果定向的教育和引导。 相似文献
144.
已有研究表明,上行比较对高自尊个体产生积极效应。然而鉴于高自尊包括安全性高自尊和防御性高自尊,有必要在上行比较影响不同任务领域内的行为表现这一观点的基础上探讨高自尊的不同类型对上行比较与行为表现之间关系的影响。两个实验均采用高自尊类型、上行比较和任务领域一致性的2×2×2混合因素设计,不同之处在于其分别采用创造性测验和非创造性的语词测验作为不同领域任务。结果表明,防御性高自尊个体没有像安全性高自尊个体那样采取领域转换策略来修复自我关注,由上行比较所引起的领域转换只对安全性高自尊个体产生积极影响。 相似文献
145.
146.
Stress can disrupt endocrine signalling in the male reproductive axis through high concentrations of glucocorticoids, the hallmark of stress. Our previous work revealed that a stress level of exogenous glucocorticoids could induce apoptosis of rat Leydig cells, which are the primary source of testosterone. The aim of this study was to investigate whether stress can induce apoptosis in rat Leydig cells in vivo and, if so, whether the process is the result of a direct effect of glucocorticoids. In a chronically stressed rat model, serum corticosterone concentration was increased significantly whereas serum testosterone was decreased. The frequency of apoptotic Leydig cells in stressed rats was also increased. Adrenalectomised rats subjected to chronic stress showed an elevated serum testosterone, while the apoptotic frequency of Leydig cells was not increased. It was established that glucocorticoid-induced Leydig cell apoptosis is mediated by glucocorticoid receptors (GRs), which translocate from cytoplasm to nucleus. Adenovirus microRNA-induced downregulation of GR expression in vitro alleviated the corticosterone-induced increase in apoptosis of Leydig cells. These results indicate that the stress-induced increase in corticosterone secretion resulted in apoptosis in rat Leydig cells in vivo, and thereby decreased testosterone synthesis. 相似文献
147.
It is established that stress impairs spatial learning and memory via the hypothalamus-pituitary-adrenal axis response. Dopamine D1 receptors were also shown to be responsible for a stress-induced deficit of working memory. However, whether stress affects the subsequent emotional learning and memory is not elucidated yet. Here, we employed the well-established one-trial step-through task to study the effect of an acute psychological stress (induced by tail hanging for 5, 10, or 20?min) on emotional learning and memory, and the possible mechanisms as well. We demonstrated that tail hanging induced an obvious stress response. Either an acute tail-hanging stress or a single dose of intraperitoneally injected dopamine D1 receptor antagonist (SCH23390) significantly decreased the step-through latency in the one-trial step-through task. However, SCH23390 prevented the acute tail-hanging stress-induced decrease in the step-through latency. In addition, the effects of tail-hanging stress and/or SCH23390 on the changes in step-through latency were not through non-memory factors such as nociceptive perception and motor function. Our data indicate that the hyperactivation of dopamine D1 receptors mediated the stress-induced deficit of emotional learning and memory. This study may have clinical significance given that psychological stress is considered to play a role in susceptibility to some mental diseases such as depression and post-traumatic stress disorder. 相似文献
148.
149.
Wang RF 《Psychonomic bulletin & review》2012,19(4):575-587
The issue of reference frame is central to theories of spatial representations. Various classifications have been made for different types of reference frames, along with prototypical research paradigms to distinguish between them. This article focuses on the configuration error paradigm proposed by Wang and Spelke (Cognition 77:215-250, 2000) that has been used to examine the nature of the spatial representations underlying object localization during self-movement. Three basic models of spatial memory and spatial updating are discussed, as well as the assumptions behind the configuration error paradigm, to distinguish between static representations, such as the traditional allocentric cognitive map and the egocentric snapshots, and dynamic representations, such as the egocentric updating system. Recent experimental findings are reexamined and shown to be consistent with multiple models, among which the egocentric-updating-and-reload model with an enduring egocentric component provides the simplest interpretations. 相似文献
150.
Rivkin A Alexander RC Knighton J Hutson PH Wang XJ Snavely DB Rosah T Watt AP Reimherr FW Adler LA 《Journal of attention disorders》2012,16(8):664-674
Objective: Preclinical models, receptor localization, and genetic linkage data support the role of D4 receptors in the etiology of ADHD. This proof-of-concept study was designed to evaluate MK-0929, a selective D4 receptor antagonist as treatment for adult ADHD. Method: A randomized, double-blind, placebo-controlled, crossover study was conducted in adults with primary ADHD. The primary end point was changed from baseline in total score on the Adult ADHD Investigator Symptom Rating Scale following a 4-week treatment regimen. Additional measures included Clinical Global Impression-Severity Scale, Hospital Anxiety and Depression Scale, and Brown Attention Deficit Disorder Scale and D4 genotype analysis. Results: No statistically significant treatment differences were found between MK-0929 and placebo in any of the primary or secondary assessments. Conclusion: Results from this study suggest that blockade of the D4 receptor alone is not efficacious in the treatment of adult ADHD. 相似文献