An fMRI study on conceptual, grammatical, and morpho-phonological processing

The aim of the present study was to determine whether processing of syntactic word information (lemma) is subserved by the same neural substrate as processing of conceptual or word form information (lexeme). We measured BOLD responses in 14 native speakers of German in three different decision tasks, each focussing specifically on one level of lexical processing (conceptual, syntactic, and morpho-phonological). The test parameters were natural gender, grammatical gender, and word form derivation, respectively. Discrimination between words played backwards and complex sounds served as control task. Complex contrasts revealed a functional fractionation of the left inferior frontal gyrus for each level of lexical processing.     

Dana-Farber Cancer Institute ethics rounds: life-threatening illness and the desire to adopt

Originally presented during Ethics Rounds at the Dana-Farber Cancer Institute, this commentary on the case of a patient treated for life-threatening cancer explores the responsibilities of health care providers when addressing the patient's desire to adopt a child.     

Construct validity of the Balloon Analog Risk Task (BART): associations with psychopathy and impulsivity

To continue research assessing the validity of the Balloon Analog Risk Task (BART) as a measure of risk taking, the BART was administered to a nonforensic sample of individuals with varying levels of psychopathic characteristics. Construct validity of the BART was evaluated by measuring risk-taking behavior in relation to self-reported psychopathy, anxiety, psychophysiological data, and demographic variables. Supporting the construct validity of the BART, while controlling for variance accounted for by interrelated variables in the context of hierarchical regression analyses, higher self-reported psychopathy was significantly predictive of increased risk taking on the BART. Findings also revealed interesting gender differences in self-reported psychopathy and a trend for men to engage in riskier behavior. Limitations and research directions are presented.     

Enhancement of auditory fear conditioning after housing in a complex environment is attenuated by prior treatment with amphetamine

Prior exposure to drugs of abuse has been shown to occlude the structural plasticity associated with living in a complex environment. Amphetamine treatment may also occlude some cognitive advantages normally associated with living in a complex environment. To test this hypothesis we examined the influence of prior exposure to amphetamine on fear conditioning in rats housed in either a standard or complex environment. Housing in a complex environment facilitated fear learning to an auditory conditioned stimulus (CS), but not to the training context, relative to animals housed singly or in a social group. Prior treatment with amphetamine eliminated this effect. These results indicate that living in a complex environment facilitates conditional freezing to an auditory CS, and that this effect is abolished by pretreatment with amphetamine.     

Attention capture is modulated in dual-task situations

Because some features affect the efficiency of visual search even when they are irrelevant to the task, they are thought tocapture attention in a stimulus-driven manner. If such attention shifts are stimulus driven, they should be unaffected by reduced resources. We added a concurrent auditory task to a traditional attention capture paradigm and found that capture by an irrelevant, abruptly appearing stimulus (i.e., an onset) was eliminated. In contrast, prioritization of an irrelevant color singleton—a stimulus that at most receives only mild prioritization in this paradigm—was increased under dual-task conditions. These results challenge the hypothesis that attention capture by irrelevant features is stimulus driven. Instead, prioritization depends on and is modulated by the availability of resources.     

A national survey of health care administrators' views on the importance of various chaplain roles

A random sample of hospital administrators throughout the United States was surveyed about their views on the importance of eleven chaplain roles and functions. The 494 respondents fell into three categories: (1) directors of pastoral care departments (N = 132); (2) administrators of hospitals that have a pastoral care department (N = 180); and (3) administrators of hospitals that do not have a pastoral care department (N = 182). All three groups considered all eleven roles to be relatively important, although administrators of hospitals that do not have a pastoral care department gave lower ratings, overall. Meeting the emotional needs of patients and relatives were seen as chaplains most important roles, whereas performing religious rituals and conducting religious services were seen as least important by all three groups. In all but a few instances, the level of importance that administrators assigned to the various roles were positively related to their ratings of their own religiousness and spirituality (r's = .11 to .26, p < .05).     

Cognitive behaviour therapy for panic disorder: long-term follow-up

This paper describes a long-term follow-up of patients with panic disorder who received cognitive behaviour therapy within a randomized controlled trial. Of 89 patients eligible for follow-up, 28 (31.5%) were reassessed 6-8 years after commencement of treatment in the trial. No differences were found between those who were followed up and those lost to follow-up on most baseline measures including measures of panic-related psychopathology, or depression. Outcomes at long-term follow-up were significantly better than baseline measures of panic, avoidance and depression. In this sub-sample the effect of cognitive behaviour therapy for panic disorder appears to maintain over the long-term.     

Visual skills in airport-security screening

Abstract— An experiment examined visual performance in a simulated luggage-screening task. Observers participated in five sessions of a task requiring them to search for knives hidden in x-ray images of cluttered bags. Sensitivity and response times improved reliably as a result of practice. Eye movement data revealed that sensitivity increases were produced entirely by changes in observers' ability to recognize target objects, and not by changes in the effectiveness of visual scanning. Moreover, recognition skills were in part stimulus-specific, such that performance was degraded by the introduction of unfamiliar target objects. Implications for screener training are discussed.     

Impact of recent findings on study design of future autism clinical trials

There are specific challenges to studying the design of pharmacologic trials in child/adolescent and adult autism, such as subject stratification and parallel versus crossover designs. This article describes how optimal study design is influenced by subject selection and outcome measures chosen. Lessons learned in study design from the Research Units on Pediatric Psychopharmacology Autism Network trial with risperidone, Seaver Center trials with fluoxetine and valproate, Dartmouth trials with amantadine, and National Institutes of Health secretin trials are highlighted. The Internet System for Assessing Autistic Children system for managing multicenter clinical trials in autism and statistical issues in autism research are also described.     

Coping with threat and memory for ambiguous information: testing the repressive discontinuity hypothesis

Two studies examined the influence of coping dispositions (repression, sensitization, and nondefensiveness) and anxiety on the encoding and memory representation of ambiguous threat-related stimuli. In Study 1, memory was tested shortly after encoding. Study 2 contrasted immediate and delayed testing. Repressers showed evidence of "mixed" affective reactions to ambiguous stimuli at encoding, accompanied by weak memory representation of potentially threatening implications of these stimuli. In contrast, sensitizers and anxious individuals manifested a processing bias in favor of threatening implications of ambiguous stimuli. Influences of coping on memory were most pronounced for delayed testing. Anxiety influences on memory were weak. An expectancy-based account of individual differences in processing ambiguous stimuli is discussed.