Ignorance is no excuse: moral judgments are influenced by a genetic variation on the oxytocin receptor gene

Perspective-taking has become a main focus of studies on moral judgments. Recent fMRI studies have demonstrated that individual differences in brain activation predict moral decision making. In particular, pharmacological studies highlighted the crucial role for the neuropeptide oxytocin in social behavior and emotional perception. In the present study N=154 participants were genotyped for a functional polymorphism (rs2268498) in the promoter region of the OXTR gene. We found a significant difference between carriers and non-carriers of the C-allele in exculpating agents for accidental harms (F((1,152))=11.49, p=.001, η(2)=.07) indicating that carriers of the C-allele rated accidentally committed harm as significantly more blameworthy than non-carriers. This is the first study providing evidence for a genetic contribution to moral judgments.     

Abh?ngigkeitserkrankungen und Pers?nlichkeitsst?rungen

Substance use disorders and personality disorders often co-occur in clinical treatment. In this review the association between substance use disorders and personality disorders is described and discussed. Clinical and neurobiological data as well as psychodynamic concepts are included to focus on the therapeutic implications for patients with these comorbidities. The consumption of substances often begins as a kind of self-medication. Patients suffering from severe personality disorders need these substance effects to avoid severe destructive affects and to regulate their self-esteem. Patients with chronic substance dependence often show changes in brain structure. In the dependency stage of addiction clinical symptoms can make the diagnosis of a specific personality disorder very difficult. The treatments can be classified by the severity of substance use disorders and personality disorders. Substance misuse can be treated with psychotherapy. In substance dependence, specific forms of addiction therapy should be included. In patients with the frequent comorbidity of substance use disorders and severe personality disorders, disorder-specific treatment can be used with good results.     

Different standards are not double standards: all elective surgical patients are not alike

Testa and colleagues argue that evaluation for suitability for living donor surgery is rooted in paternalism in contrast with the evaluation for most operative interventions, which is rooted in the autonomy of patients. We examine two key ethical concepts that Testa and colleagues use: paternalism and autonomy, and two related ethical concepts: moral agency and shared decision making. We show that by moving the conversation from paternalism, negative autonomy, and informed consent to moral agency, relational autonomy, and shared decision making, one better understands why the arguments given by Testa and colleagues fail. We argue (1) why the hurdles that one must overcome to become a living donor are appropriate; and (2) that the similarities between living donor transplant surgery and cosmetic plastic surgery that the authors describe are inaccurate. Finally, we consider the recommendation to treat plastic surgery patients and living donors more similarly. We argue that any change should not be in the direction of becoming less protective of living donors, but more protective of cosmetic plastic surgery candidates.     

Enumeration of small and large numerosities: the effect of element visibility

Precise enumeration is associated with small numerosities within the subitizing range (<4 items), while approximate enumeration is associated with large numerosities (>4 items). To date, there is still debate on whether a single continuous process or dual mutually exclusive processes mediate enumeration of small and large numerosities. Here, we evaluated a compromise between these two notions: that the precise representation of number is limited to small numerosities, but that the approximate representation of numerosity spans across both small and large numerosities. We assessed the independence of precise and approximate enumeration by looking at how luminance contrast affected enumeration of elements that differ by ones (1-8) or by tens (10-80). We found that enumeration functions of ones and tens have different characteristics, which is consistent with the presence of two number systems. Subitizing was preserved for small numerosities. However, simply decreasing element visibility changed the variability signatures of small numerosities to match those of large numerosities. Together, our results suggest that small numerosities are mediated by both precise and approximate representations of numerosity.     

The Role of Threat in Attitudes Toward Affirmative Action and Its Beneficiaries1

This set of two studies employed the integrated threat theory to examine attitudes toward affirmative action (AA). The first study found that opposition to the policy of AA was predicted by realistic threats, symbolic threats, and personal relevance; while attitudes toward the beneficiaries of AA were predicted by three of the four threat variables (symbolic threats, intergroup anxiety, and negative stereotypes), and in‐group identity. The second study replicated and expanded on the first study and found that the effects of several individual‐difference variables (racism, anti‐Black affect, and political conservatism) on opposition to AA were mediated by three of the threats in the integrated threat theory (realistic threats, symbolic threats, and negative stereotypes). The implications of the results are discussed.     

Applying Meta-theory to Achieve Generalisability and Precision in Personality Science

In contrast to traditional theories of personality, the CAPS perspective is a meta-theory that is deliberately "content-free". The generalisability of the theory depends on how widely its basic, common principles and methods can be applied to identify the constructs (e.g. situation-specific encodings, beliefs, values, etc.) relevant to a given domain of behavior and situations. In this commentary we will discuss how the target article illustrates the use of the CAPS meta-theory for developing domain-specific content-full models for smoking cessation, psychopathology, and organisational behavior.     

Family constellations and friendship systems

An individual friendship system is composed of the friends a person has had and/or still has. Individual friendship systems can be characterized objectively in similar ways as can family constellations. The data of a questionnaire study of individual friendship systems and respective family backgrounds of more than 400 subjects revealed greater differentiation and variation with age as well as with the presumed absence of conflict, disruption, and loss in a person's social development. Various interactions between family backgrounds could be traced. To illustrate the practical use of characteristics of a person's individual friendship system two clinical cases matched for age and family background, one with a mild neurotic problem and the other severely disturbed, were compared.Based on a lecture first given at the Family Therapy Symposium of Georgetown University, Washington, DC, on November 9, 1986.