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801.
S. B. DUNNETT F. H. GAGE A. BJÖRKLUND U. STENEVI W. C. LOW S. D. IVERSEN 《Scandinavian journal of psychology》1982,23(S1):104-111
A brief review is provided of the capacity of neural tissue transplants to reinnervate the deafferented hippocampus and repair functional deficits induced by the lesion. The techniques for transplantation of solid pieces of embryonic septum, locus coeruleus or raphe nuclei, or tissue suspensions of embryonic septum, to the adult rat hippocampus are described. Such grafts manifest good long-term survival, provide a good reinnervation of the hippocampus that is histochemically and biochemically appropriate and specific, can establish ultrastructural synaptic contacts with the host, and are electrophysiologically active. Rats with septal grafts manifest recovery of the capacity to learn certain aspects of radial 8-arm maze, T-maze alternation and Morris water-maze tasks. Rats with locus coeruleus grafts manifest an amelioration of lesion-induced hyperactivity. It is concluded that neural tissue transplantation provides a powerful new tool in the study of the functional organization of the hippocampus and its various neurotransmitter-specific afferent systems. 相似文献
802.
F. H. GAGE S. B. DUNNETT A. BJÖRKLUND U. STENEVI 《Scandinavian journal of psychology》1982,23(S1):112-120
Mammals are well known to manifest recovery over time of many functional impairments induced by brain lesions. A brief reveiw is provided of the different conceptual frameworks within which functional recovery has been examined in the literature, and of different neurobiological mechanisms that have been proposed to account for the phenomenon. We observe that these two levels of analysis have frequently been only loosely related. Finally, a newly identified biological mechanism—compensatory collateral sprouting—is described which appears to be closely related to functional recovery in animals with hippocampal lesions, and this is proposed as a powerful new model within which to investigate further the relationship between the phenomenon of functional recovery and its underlying mechanisms. 相似文献
803.
804.
F. Gregory Ashby 《Memory & cognition》1982,10(2):125-134
Two assumptions commonly made by choice reaction time (RT) models are (1) that certain experimental tasks can be found that cause an extra processing stage to be inserted into the cognitive process and (2) that the duration of one or more processing stages is random with an exponential distribution. Few rigorous tests of either assumption exist. This paper reviews existing tests and presents several new results that can be used to test these assumptions. First, in the case in which the duration of an inserted stage is exponentially distributed, it is shown that the observable RT density functions must always intersect at the mode of the density requiring the extra processing stage. Second, when only the first assumption (Assumption 1) is made, it is shown that the cumulative RT distribution functions and, in many cases, the hazard functions must be ordered. Finally, when only Assumption 2 is assumed, it is shown that, under fairly weak conditions, the taft of the RT density function must be exponential. The first two results are applied to data from a memory scanning experiment, and the two assumptions are found to receive tentative support 相似文献
805.
Mental shock can produce retrograde amnesia 总被引:1,自引:0,他引:1
Subjects in three experiments saw a short film of a mentally shocking event in which a young boy is violently shot in the face. Compared to other subjects who saw a nonviolent version of the same film, those who saw the mentally shocking version showed poorer retention of the details of the film. Retention was poorer whether measured by recognition or recall. Furthermore, impaired memory occurred only when the event was mentally upsetting, and not when it was merely unexpected but not upsetting. These results suggest that mentally shocking episodes may disrupt the lingering processing necessary for full storage of information in memory. 相似文献
806.
807.
The language patterns of 10 mothers and 10 fathers with their firstborn 3-year-old sons were compared. Ten-minute mother-son and father-son conversations were recorded independently in the home during a free-play session with standard play mterials. The findings of this study indicate that although mothers and fathers used a similar number of utterances in conversing with their sons over a 10-minute period, their patterns of speech were different on a number of quantitative measures including MLU, MLU of five longest utterances, percent of imperatives, and percent of questions. In general, fathers' communication was viewed as more controlling and involving the child less, while mothers' communication was viewed as more child-centered and involving the child more. 相似文献
808.
809.
Two pilot studies and two experiments were conducted to test for relationships between mood states, self-reflection, and helpfulness. It was hypothesized that both negative and positive feelings would increase helpful reactions. In the case of negative moods, however, helpfulness would be inhibited if the induced affect engenders self-reflection by associating the bad mood with the person's self-image in a self-referencing process. To test these predictions, female undergraduates read mood-inducing statements that were either (a) negative in content and containing the personal pronoun “I”, (b) negative but not self-referencing, (c) emotionally positive in content, (d) emotionally neutral, or (e) no statements. Afterward, they were asked to complete a questionnaire and to volunteer to participate in a future study. Findings in the first experiment confirmed the hypothesis. Women who had read negative, self-referencing statements were the least likely to comply with a helpful request. The most helpful participants were those who had previously recited the negative, but not self-referencing, and the positive statements. Neutral and control subjects displayed intermediate amounts of compliance with the helping request. Questionnaire results showed that self-reflection was responsible for decreasing the helpfulness of women when negative mood was associated with some aspect of the self. A second experiment successfully replicated the major findings of the pilot studies and the first experiment. 相似文献
810.