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It is important to study communication processes in families where members are undergoing testing for genetic conditions because the information received from such testing is crucial not just to the individual concerned but also to other members of the biological family. This topic has received little research attention, in part because of the complexities of methodology required. In this paper we present the development of a method specifically designed for the examination of the content and process of communication of genetic information in families. The method aims to maximize ecological validity as far as is possible. We describe how participants and other family members are recruited and how data were collected. We outline three main data analytic strategies: a graphic to show how genetic information changes as it flows from clinic and through the family, an intensive qualitative analysis of the meaning and impact of the genetic information to different family members, and an informative genogram which plots key family dynamics. This method will be illustrated in relation to a study of ten family-groups where one individual has been found to carry a genetic mutation predisposing them to hereditary breast and ovarian cancer.  相似文献   
174.
Two experiments with left-handers examined the features of prism adaptation established by previous research with right-handers. Regardless of handedness, (1) rapid adaptation occurs in exposure pointing with developing error in the opposite direction after target achievement, especially with early visual feedback in target pointing; (2) proprioceptive or visual aftereffects are larger, depending on whether visual feedback is available early or late, respectively, in target pointing; (3) the sum of these aftereffects is equal to the total aftereffect for the eye-hand coordination loop; (4) intermanual transfer of visual aftereffects occurs only for the dominant hand; and (5) visual aftereffects are larger in left space when the dominant hand is exposed to leftward displacement. A notable handedness difference is that, while transfer of proprioceptive aftereffects only occurs to the nondominant hand in right-handers, transfer occurs in both directions for left-handers, but regardless of handedness, such transfer only occurs when the exposed hand is tested first after exposure. A discussion then focuses on the implications of these data for a theory of handedness.  相似文献   
175.
Left-hemisphere activation and deficient response modulation in psychopaths   总被引:1,自引:0,他引:1  
Psychopathic offenders have difficulty processing contextual or secondary cues once they have initiated goal-directed behavior or allocated attention to a primary task. To test the hypothesis that this deficit in response modulation is specific to conditions in which psychopaths' left-hemisphere resources are engaged, we administered a serial recall task to 21 incarcerated psychopaths and 21 control subjects. Subjects were instructed to memorize eight words that were presented one at a time, each in one of the four corners of the visual display. Subjects' primary task was to recall the words in serial order. Then, without forewarning, they were asked to recall the words' locations. As predicted, psychopaths performed as well as control subjects in recalling words from the left and right spatial fields, but recalled significantly fewer locations from the right spatial field. Thus, psychopaths' deficient response modulation was specific to conditions in which their left-hemisphere resources were actively engaged.  相似文献   
176.
In this article, the authors describe the refinement and preliminary evaluation of the Dimensions of Change in Therapeutic Community Treatment Instrument (DCI), a measure of treatment process. In Study 1, a 99-item DCI, administered to a cross-sectional sample of substance abuse clients (N = 990), was shortened to 54 items on the basis of results from confirmatory factor analyses and item response theory invariance tests. In Study 2, confirmatory factor analyses of the 54-item DCI, completed by a longitudinal cohort of 993 clients, established and validated an 8-factor solution across 2 subpopulations (adults and adolescents) and 2 time points (treatment entry and 30-days postentry). The results of the 2 studies are encouraging and support use of the 54-item DCI as a tool to measure treatment process.  相似文献   
177.
New structural and functional imaging methods continue to be developed at a rapid pace. In the last 25 years, advanced imaging techniques have provided insights into how language is represented and processed in the brain and how it can be disrupted by damage to, or dysfunction of, various parts of the brain. Imaging studies have also yielded new information regarding how individuals recover language after stroke. We briefly review the strengths and weaknesses of the various radiological methods currently used to study language and aphasia.  相似文献   
178.
Human and rat movement organization was investigated as they searched for randomly located rewards without access to visual information. Under dark conditions, rats foraged for randomly located food pellets (Experiment 1). Blindfolded humans were instructed to search for an ostensible hidden coin using a metal detector (Experiment 2). After locating the food pellet, rats carried it back to the refuge, and after a designated searching time, humans were instructed to return to the start location. Although both species exhibited a high degree of similarity in searching path movement organization and ability to return to the start location, disruption of human searching path organization was associated with impairments in returning to the start location. These results support the vestibular "gain" account of movement organization during dead-reckoning-based navigation.  相似文献   
179.

Announcement

Diplomates Certified in 2005  相似文献   
180.
Wallace A  Liljequist L 《Assessment》2005,12(3):290-294
The relationship between the MMPI-2 restructured clinical scales and the original clinical scales was evaluated using an outpatient clinical sample (N = 150). Similar patterns of correlations to those reported by Tellegen et al. in 2003, such as high correlations between the restructured scales and their original scale counterparts and lower intercorrelations among the restructured scales than among the original scales, were found in the outpatient sample. The former provided evidence of convergence between the two sets of scales, whereas the latter increases the potential for discriminant validity in the restructured scale profiles. Mean T-scores of the restructured scales were significantly lower than their original scale counterparts for every clinical scale except Scale 1 (hypochondriasis). Individual profiles exhibited fewer scale elevations using the restructured clinical scales (M = 2.15, Mdn = 2.0) than the original clinical scales (M = 3.29, Mdn = 3.0). The majority of client profiles (56%) had fewer scale elevations when plotted using the restructured scales versus the original clinical scales.  相似文献   
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