Chronic sweet intake lowers pain thresholds without changing brain mu- or delta-opiate receptors

Sprague-Dawley rats drank sweetened (3% dextrose + 0.144% saccharin, w/v) or unflavored water for 18 days and subsequent pain reactivity was assessed using a hot plate. Compared to the rats that consumed unflavored water, the rats that consumed sweet water responded more quickly on the hot plate indicating that their threshold for pain was lowered. Another group of rats given identical exposure to the fluids had their brains prepared for measuring opiate receptor binding using the delta-receptor ligand [3H]D-Ala-D-Leu-enkephalin ([3H]DADLE) and the mu-receptor selective ligand [3H]Tyr-D-Ala-Gly-MePhe-Gly-ol ([ 3H]DAGO). Binding of these opiates to mu- and delta-receptors in the cerebral cortex, striatum, hippocampus, hypothalamus, brain stem, and remaining brain regions was the same for the rats that drank sweet fluids and those that drank unflavored water. These findings suggest that drinking sweet fluids lowers pain thresholds but does not alter mu- and delta-receptors.     

Emotional sequelae of abortion: implications for clinical practice

For women in therapy who have had abortions, an exploration of the context and aftermath of each abortion has been suggested. This inquiry should include: characteristics of the woman herself before and at the time of the abortion, the nature of the interpersonal and cultural milieu at the time, characteristics of the medical environment and procedure, and any events subsequent to the abortion that may evoke regrets about the earlier decision.
Whether or not such an inquiry results in the identification of unresolved issues surrounding the abortion, it is likely to enhance one's general understanding of the client. Exploring a woman's decision to have an abortion can bring into relief developmental and family issues, relationship conflicts, and her aspirations for education, work, and family. A woman's approach to establishing and asserting her priorities and values in making difficult personal decisions becomes clear as does her ability to tolerate and resolve the ambivalence inherent in making difficult decisions.
In psychotherapy, it is important to understand and address those aspects of experience that women have difficulty resolving. Hence, the emphasis on categories of experience that may have a negative impact on a woman's emotional well-being after abortion. Nevertheless, the clinician should remember that even women who report negative post-abortion sequelae overwhelmingly report that they feel that the decision was the right one for them. Having ambivalent feelings to resolve does not necessarily mean that one has made a wrong choice, only that one has made an emotionally significant choice with far-reaching personal implications, in a sociocultural environment that reinforces the ambivalence inherent in such decisions.     

Reversal of genetic homeostasis in laboratory populations of Drosophila melanogaster under long-term selection for geotaxis and estimates of gene correlates: evolution of behavior-genetic systems

Among Drosophila melanogaster, divergently selected for geotaxis intermittently over 600 generations (28 years), about 80,000 animals have been analyzed behavior-genetically. Each major chromosome pair from two lines was isogenized on an unselected isogenic background. Measurement of their behavioral effects revealed the relative magnitudes II greater than III greater than X for the negatively geotactic (high) line and X greater than III greater than II for the positively geotactic (low) line. When reversing selection for the now phenotypically stable high and low lines and then repeatedly relaxing the reversals, a new genetic homeostasis in the low line was indicated by the return of the reversed-line average scores towards the low extreme; that is, the low line has attained a stable equilibrium for positive geotaxis, an uncharacteristic behavior and an effect not seen before 1979. This change suggests the recent evolution of a new coadaptation among genes. Although not as conclusive, a similar genetic interpretation is suggested for the high line.     

Learning from lectures: The effect of varying the detail in lecture handouts on note-taking and recall

Previous research on the effect of lecture handouts on student learning indicates that students who are given skeletal handouts usually perform better in course examinations than students who take all their own notes. The present study investigates whether the amount of detail in the handout is a critical factor in this. A randomized groups experiment was conducted in the context of a course on dental surgery. Four lecture handout conditions (headings and full text; headings and key points; headings only; no supplementary materials) were compared on tests 2 days and 2 weeks after the lecture. The significant differences between conditions were: ‘headings only’ better than ‘headings and key points’ on the first test; ‘headings only’ better than ‘no supplementary materials’ on the second test; and ‘headings and full text’ better than ‘no supplementary materials’ on the second test. These results indicate that the amount of detail is a critical factor in handout effectiveness.     

Visual perception during naturalistic near-death out-of-body experiences

This study attempted to ascertain the most appropriate content and placement of visual stimuli in a hospital-based study of the veridicality of out-of-body perception in the near-death experience (NDE), and the likelihood that a subject in such a study would notice, clearly perceive, and accurately recall a visual stimulus. Based on the questionnaire responses of 63 subjects who had near-death out-of-body experiences (ND OBEs), at least some of the respondents described sufficiently complete and accurate visual perception during the experience to warrant the pursuit of veridicality research in hospitals. Recommended stimulus content for such research includes a surface with intense color and lighting, and simple number and/or letter combinations. Stimuli should be as far below ceiling level as possible while maintaining double-blind criteria. Some characteristics of the individual NDE and NDEr may affect veridical perception during the ND OBE.This paper was derived in part from her Ed.D. dissertation submitted to the Northern Illinois University Graduate School.     

Ego,moral, and faith development in near-death experiencers: Three case studies

Near-death experiencers (NDErs) commonly report shifts in basic values and attitudes, toward intensified compassion and a sense of unconditional love, sprituality, and a sense of mission, and away from materialism and competitiveness. Some researchers have suggested that these attitudinal shifts represent a new stage in human evolution, which will produce major social change. However, knowledge of these reputed NDE aftereffects has been based on NDErs' subjective reports, unverified by objective measures. This study examined relationships between three NDErs' levels of moral, ego, and faith development, as measured by standardized instruments, and extensive qualitative data describing their NDEs and personal attributes. The results suggest that currently available instruments, designed to measure the lower self, may not reflect the awakening to a transpersonal plane of functioning that follows an NDE.Dr. Newsome is in the private practice of psychotherapy and counseling. This paper was derived in part from her Ph.D. thesis submitted to Walden University.     

The Tichborne Claimant: Person identification following very long intervals

An account is given of the nineteenth-century case of the Tichborne Claimant, in which someone purporting to be Sir Roger Tichborne, a missing heir, arrived in England from Australia 13 years after Sir Roger had been assumed drowned at sea. Many people, including Lady Tichborne, Sir Roger's mother, positively identified him. Others insisted that he was an impostor. A civil court and a criminal trial each found against The Claimant for various reasons, but the question of The Claimant's true identity remains open to this day. The case of the Tichborne Claimant is used to illustrate issues in identification that are of contemporary interest. The particular matter of how faces change over time is briefly discussed.     

Advancing knowledge about delinquency and crime: The need for a coordinated program of longitudinal research

Past research on delinquency and crime has provided convincing data about correlates but not about causes, because it has been largely cross-sectional in design. Whereas cross-sectional research focuses on variations between subjects, longitudinal research can provide information about changes within subjects, which are more important for causes, prevention, and treatment. Many of the most important results in criminology have been obtained in longitudinal or experimental studies, and the major studies of these types are reviewed here. It is now desirable to combine the two methods in a new coordinated program of longitudinal studies including experimental interventions or quasi-experimental analyses. Such projects could study several overlapping cohorts, extend from birth to adulthood, have frequent data collection, and obtain data from a variety of sources about many different types of antisocial behavior.