Determination of dipeptidyl aminopeptidase activities in the cerebrospinal fluid

The investigation of enzyme activity in cerebrospinal fluid has been without relevant results for laboratories analysing spinal fluid. For neurochemical purposes, it is interesting that the Substance P is convered by Depeptidyl-aminopeptidase IV (DP IV), liberating dipeptides. The hydrolysis of nitroanilids of the form Xaa-Pro-NHNp in cerebrospinal fluid was analysed using them as peptidases substrates. Finally a method for measuring the activity was proposed.     

Acoustically evoked brain stem potential in Wilson disease

By 48 patients with Wilson's disease the brainstem acoustic evoked potentials were stated. There were 35 pathological findings (73%), 13 were normal (27%). The waves, determined by the middle and upper brainstem (Pons and Mesencephalon) showed most of all pathological changes. Those patients with forms of Wilson's disease called Pseudoskelerose and Pseudoparkinson showed the most pathological findings. But one could watch these findings by about 30% of patients in preclinical stage. This method can possibly be used for early detection of disorders of brainstem functions and in the same way it can be used for control of treatment by patients in preclinical stage.     

On tests for correlated proportions in the presence of incomplete data

This paper proposes test statistics based on the likelihood ratio principle for testing equality of proportions in correlated data with additional incomplete samples. Powers of these tests are compared through Monte Carlo simulation with those of tests proposed recently by Ekbohm (based on an unbiased estimator) and Campbell (based on a Pearson-Chi-squared type statistic). Even though tests based on the maximum likelihood principle are theoretically expected to be superior to others, at least asymptotically, results from our simulations show that the gain in power could only be slight.     

Some definitions of negation leading to paraconsistent logics

In positive logic the negation of a propositionA is defined byA X whereX is some fixed proposition. A number of standard properties of negation, includingreductio ad absurdum, can then be proved, but not the law of noncontradiction so that this forms a paraconsistent logic. Various stronger paraconsistent logics are then generated by putting in particular propositions forX. These propositions range from true through contingent to false.     

Why 2 + 2 = 5 looks so wrong: On the odd-even rule in sum verification

The odd-even status of a sum depends on the odd-even status of its addends. A sum must be odd if an odd number of its addends are odd; else it must be even. A proposed sum that violates the required odd-even status of the sum—that is, deviates from the correct sum, whether odd or even, by an odd value (e.g., splits of ±1, ±3, ±5)—can be rejected immediately as false. Subjects in the present study did indeed use the odd-even rule in sum verification, because they were as fast and accurate in rejecting a split of ±1 as one of ±2, and a split of ±3 as one of ±4, even though a larger split generally is easier to reject (symbolic distance effect), and splits of ±3 and ±4 were rejected faster and more accurately than those of ±1 and ±2. Performance on separate odd-even tasks indicated that the odd-even properties of numbers and sums are readily available for use by adults, and that persons who do well on such tasks are especially likely to use the odd-even rule in sum verification.