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131.
Hormonal and monoamine signaling during reinforcement of hippocampal long-term potentiation and memory retrieval 总被引:2,自引:0,他引:2
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Recently it was shown that holeboard training can reinforce, i.e., transform early-LTP into late-LTP in the dentate gyrus during the initial formation of a long-term spatial reference memory in rats. The consolidation of LTP as well as of the reference memory was dependent on protein synthesis. We have now investigated the transmitter systems involved in this reinforcement and found that LTP-consolidation and memory retrieval were dependent on β-adrenergic, dopaminergic, and mineralocorticoid receptor (MR) activation, whereas glucocorticoid receptors (GRs) were not involved. Blockade of the β-adrenergic signaling pathway significantly increased the number of reference memory errors compared with MR and dopamine receptor inhibition. In addition, β-adrenergic blockade impaired the working memory. Therefore, we suggest that β-adrenergic receptor activation is the main signaling system required for the retrieval of spatial memory. In addition, other modulatory interactions such as dopaminergic as well as MR systems are involved. This result points to specific roles of different modulatory systems during the retrieval of specific components of spatial memory. The data provide evidence for similar integrative interactions between different signaling systems during cellular memory processes. 相似文献
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An extension of latent state-trait (LST) theory to hierarchical LST models is presented. In hierarchical LST models, the covariances between 2 or more latent traits are explained by a general 3rd-order factor, and the covariances between latent state residuals pertaining to different traits measured on the same measurement occasion are explained by 2nd-order latent occasion-specific factors. Analogous to recent developments in multitrait-multimethod methodology, all factors are interpreted in relation to factors taken as comparison standards. An empirical example from test anxiety research illustrates how estimates of additive variance components due to general trait, specific trait, occasion, state residual, method, and measurement error can be obtained using confirmatory factor analysis. Advantages and limitations of these models are discussed. 相似文献
134.
How do men and women describe and assess their relationship? What themes are decisive for its quality and stability? To answer such questions, we investigated a random sample of 204 married couples (reference sample), and 31 married couples undergoing psychotherapy (clinical sample) using a newly developed questionnaire. The participating couples were asked to evaluate a total of 19 themes with respect to their importance for the couple's connectedness. Although only rarely directly addressed in couple therapy and in‐vestigated in couple research, the theme “Love” proved to be the decisive factor for quality and stability. The results of the present study, therefore, indicate that “Love” should be investigated more thoroughly in couple research and included more actively in diagnostic and therapeutic procedures. 相似文献
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When participants are asked to shift between four dimensionally organized tasks which differ in the type of judgment (numerical vs. spatial) and/or the judgment-to-response mapping (compatible vs. incompatible), a characteristic profile of shift costs can be observed. It can be accounted for in terms of two different types of operations: generalizing switching operations on a dimensionally organized set of task representations and implementation operations [T. Kleinsorge, H. Heuer, Psycholog. Res. 62 (1999) 300]. In a first experiment we corroborated our previous findings by way of a new procedure that makes it possible to estimate shift costs unconfounded by a number of factors that are likely to affect estimates of shift costs based on more conventional procedures. In a second experiment we investigated the endogenous and exogenous nature of the postulated types of operations. The characteristic profile of shift costs disappeared when long precue intervals (PCIs) were used. Augmented by a formal analysis, this finding suggests that both switching and implementation operations are endogenously controlled. In addition, there remained some residual shift costs which were essentially insensitive to the nature of the task shift but depended on the difficulty of the new task. Most likely they reflect a process of consolidation of an already configured task set. 相似文献
137.
Volker Halbach 《Studia Logica》2001,68(3):421-422
Volume Contents
Contents of Volume 68 相似文献138.
Andrea K. Wittenborn Anthony J. Faber Ashley M. Harvey Volker K. Thomas 《The American journal of family therapy》2013,41(4):333-342
Emotionally Focused Family Therapy provides a framework for understanding children's behaviors in terms of attachment needs of comfort and support. However, when working with young children, play therapy is often developmentally preferred over “talk therapy.” By integrating play therapy techniques within an Emotionally Focused Family Therapy theoretical framework, therapists can help parents understand and meet their child's needs for affection and comfort. This article will discuss how play therapy techniques can be integrated with an Emotionally Focused Family Therapy theoretical framework for work with young children and their families. 相似文献
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Volker Thoma 《Psychonomic bulletin & review》2014,21(6):1473-1480
Previous observations that face recognition may proceed automatically, without drawing on attentional resources, have been challenged by recent demonstrations that only a few faces can be processed at one time. However, a question remains about the nature of the stimulus properties that underlie face-specific capacity limits. Two experiments showed that speeded categorization of a famous face (such as a politician or pop star) is facilitated when it is congruent with a peripheral distractor face. This congruency effect is eliminated if the visual search is loaded with more than one face, unlike previous demonstrations of speeded classification using semantic information. Importantly, congruency effects are also eliminated when the search task is loaded with nontarget faces that are shown in an inverted orientation. These results indicate that face-specific capacity limits are not determined by the configural (“holistic”) properties of face recognition. 相似文献