Spatial learning in the holeboard impairs an early phase of long-term potentiation in the rat hippocampal CA1-region

Long-term potentiation (LTP) and depression (LTD) are considered as cellular models for learning and memory. We studied the impact of holeboard training on LTP in the rat CA1 hippocampal region. In 7-week-old Wistar rats a recording electrode was chronically implanted into the hippocampal pyramidal cell layer of the CA1 of the right hemisphere and a stimulation electrode into the contralateral CA3 region.Two groups of animals received a spatial holeboard training of 10 or 15 trials over 2 days on a fixed pattern of baited holes. The last trial was performed 15 min after a primed burst stimulation of the contralateral CA3, which resulted in LTP in the ipsilateral CA1. A pseudo-trained group that received a 10 trial training with changing patterns of baited holes after each trial and a group that remained in the recording chambers during the experiments served as controls. Experimental rats significantly improved their spatial performance with increasing numbers of trials, indicated by decreasing times to pick up all food pellets and by decreasing numbers of reference memory errors. A learning-related impairment of CA1-LTP measured in both the population-spike amplitude as well as the fEPSP could be noted. These results show that specific (pattern-training), but not unspecific (pseudo-training) spatial information processing prior to electrical stimulation can severely affect LTP in hippocampal area CA1.     

Editorial Introduction

I survey some important semantical and axiomatic theories of self-referential truth. Kripke's fixed-point theory, the revision theory of truth and appraoches involving fuzzy logic are the main examples of semantical theories. I look at axiomatic theories devised by Cantini, Feferman, Freidman and Sheard. Finally some applications of the theory of self-referential truth are considered.     

Musiktherapie bei chronisch-tonalem Tinnitus

Tinnitus therapy according to the Heidelberg model of music therapy integrates psychological strategies in order to manage the perception and approaches to tinnitus aimed at curing the underlying somatic disorder. The specific musical therapeutic interventions as well as the postulated specific effective factors are explained. Several multidisciplinary studies support the effectiveness of this form of therapy. The results indicate that the therapy is highly advantageous in terms of treatment duration, effectiveness, and follow-up stability compared to customary interventions. Furthermore, the results of brain imaging strongly suggest the usefulness of further investigations and discussion in the realm of neuronal modeling of chronic tinnitus.     

On the Costs of Nonclassical Logic

Solutions to semantic paradoxes often involve restrictions of classical logic for semantic vocabulary. In the paper we investigate the costs of these restrictions in a model case. In particular, we fix two systems of truth capturing the same conception of truth: (a variant) of the system KF of Feferman (The Journal of Symbolic Logic, 56, 1–49, 1991) formulated in classical logic, and (a variant of) the system PKF of Halbach and Horsten (The Journal of Symbolic Logic, 71, 677–712, 2006), formulated in basic De Morgan logic. The classical system is known to be much stronger than the nonclassical one. We assess the reasons for this asymmetry by showing that the truth theoretic principles of PKF cannot be blamed: PKF with induction restricted to non-semantic vocabulary coincides in fact with what the restricted version of KF proves true.     

Emotionally Focused Family Therapy and Play Therapy Techniques

Emotionally Focused Family Therapy provides a framework for understanding children's behaviors in terms of attachment needs of comfort and support. However, when working with young children, play therapy is often developmentally preferred over “talk therapy.” By integrating play therapy techniques within an Emotionally Focused Family Therapy theoretical framework, therapists can help parents understand and meet their child's needs for affection and comfort. This article will discuss how play therapy techniques can be integrated with an Emotionally Focused Family Therapy theoretical framework for work with young children and their families.     

Standard errors and confidence intervals in within-subjects designs: Generalizing Loftus and Masson (1994) and avoiding the biases of alternative accounts

Repeated measures designs are common in experimental psychology. Because of the correlational structure in these designs, the calculation and interpretation of confidence intervals is nontrivial. One solution was provided by Loftus and Masson (Psychonomic Bulletin & Review 1:476-490, 1994). This solution, although widely adopted, has the limitation of implying same-size confidence intervals for all factor levels, and therefore does not allow for the assessment of variance homogeneity assumptions (i.e., the circularity assumption, which is crucial for the repeated measures ANOVA). This limitation and the method's perceived complexity have sometimes led scientists to use a simplified variant, based on a per-subject normalization of the data (Bakeman & McArthur, Behavior Research Methods, Instruments, & Computers 28:584-589, 1996; Cousineau, Tutorials in Quantitative Methods for Psychology 1:42-45, 2005; Morey, Tutorials in Quantitative Methods for Psychology 4:61-64, 2008; Morrison & Weaver, Behavior Research Methods, Instruments, & Computers 27:52-56, 1995). We show that this normalization method leads to biased results and is uninformative with regard to circularity. Instead, we provide a simple, intuitive generalization of the Loftus and Masson method that allows for assessment of the circularity assumption.     

Tool-use in the brown bear (Ursus arctos)

This is the first report of tool-using behaviour in a wild brown bear (Ursus arctos). Whereas the use of tools is comparatively common among primates and has also been documented in several species of birds, fishes and invertebrates, tool-using behaviours have so far been observed in only four species of non-primate mammal. The observation was made and photographed while studying the behaviour of a subadult brown bear in south-eastern Alaska. The animal repeatedly picked up barnacle-encrusted rocks in shallow water, manipulated and re-oriented them in its forepaws, and used them to rub its neck and muzzle. The behaviour probably served to relieve irritated skin or to remove food-remains from the fur. Bears habitually rub against stationary objects and overturn rocks and boulders during foraging and such rubbing behaviour could have been transferred to a freely movable object to classify as tool-use. The bear exhibited considerable motor skills when manipulating the rocks, which clearly shows that these animals possess the advanced motor learning necessary for tool-use. Advanced spatial cognition and motor skills for object manipulation during feeding and tool-use provide a possible explanation for why bears have the largest brains relative to body size of all carnivores. Systematic research into the cognitive abilities of bears, both in captivity and in the wild, is clearly warranted to fully understand their motor-learning skills and physical intelligence related to tool-use and other object manipulation tasks.     

Observational couple assessment: a cross-model comparison

This study compared the clinical rating scales from the Circumplex Model (CCRS), the McMaster Model of Family Functioning (MCRS) and the Family Health Scales (FHS). A central purpose was to investigate whether observational rating scales designed to measure family functioning can also be used to assess couple functioning. One hundred and sixty-six drug abusing women, receiving primary drug treatment in two metropolitan drug agencies in the southwest of the US, and their partners were videotaped while engaged in three couple tasks prior to receiving any treatment. The main findings indicated that all three rating scales have: (1) sufficient interrater reliability; (2) good construct validity, as reflected in factor analyses; and (3) very good convergent validity. However, there was some concern about whether these scales are as discriminating when measuring couples as they are when assessing families.     

Need for Family Therapy Services for Middle-Class Families in India

This qualitative study explored the needs of Indian middle-class families for family therapy services. Four focus group interviews were conducted with middle-class parents in Madras, India. Participants were introduced to the concept and practice of family therapy and were encouraged to take a more active role in supporting the services they suggested. Participants identified problems faced by Madras middle class families and five different types of services that they were aware of. Three categories of need for family therapy were identified from the narratives of the participants. Several themes fit in each of the three categories. Implications for clinical application are discussed.