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Pleasure D Soulika A Singh SK Gallo V Bannerman P 《Mental retardation and developmental disabilities research reviews》2006,12(2):141-146
While the central nervous system (CNS) is generally thought of as an immunopriviledged site, immune-mediated CNS white matter damage can occur in both the perinatal period and in adults, and can result in severe and persistent neurological deficits. Periventricular leukomalacia (PVL) is an inflammatory white matter disease of premature infants that frequently results in cerebral palsy (CP). Clinical and experimental studies show that both hypoxic/ischemic and innate immune mechanisms contribute to the destruction of immature oligodendroglia and of axons in the deep cerebral white matter in PVL. No data are yet available as to whether there is any genetic predisposition to PVL or to its neurological sequelae. Multiple sclerosis (MS) is an inflammatory white matter disease that often begins in young adulthood, causes multifocal destruction of mature oligodendroglia and of axons, and eventually leads to substantial cumulative neurological disability. Certain genetic polymorphisms contribute to susceptibility to MS, and adaptive immune responses to myelin-associated self antigens, or to exogenous antigens that mimic these self antigens, play a central role in the pathophysiology of this disease. 相似文献
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Vittorio Gallese M.D. 《Psychoanalytic Dialogues》2013,23(5):580-584
Neuroscience is progressively revealing the intimate relationship between embodied simulation and the understanding of verbal communication, including its affective quality. The neuroscientific investigation of linguistic aspects of interpersonal relations and the functional mechanism of embodied simulation are discussed in relation to the understanding of therapeutic action in psychoanalysis. 相似文献
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Guido Alessandri Gian Vittorio Caprara John Tisak 《Multivariate behavioral research》2013,48(3):341-368
The subgrouping strategy has been employed in a number of studies (Fredriksen &; Gilbert, 1960; Fredriksen &; Melville, 1964; Ghiselli, 1956; Klein, Rock &; Evans, 1968; Rock, Evans &; Klein, 1969; Malnig, 1969). In each of these studies it was shown that after partitioning a sample into g subgroups and performing a separate regression analysis within each group, one could identify one or more subgroups having a larger multiple correlation than the total sample regression. An important question is whether this type of result will be maintained under cross validation. 相似文献
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Francesca Montemaggi 《Religion》2013,43(4):642-658
The paper explores the ethical attitude of Christian evangelicals in a church in Britain and how it affects boundary-making of their community. Evangelicals in the case study seek to be accepting of the person and to refrain from being judgemental. The paper distinguishes between the person-centred ‘ethic of compassion’ and the norm-centred ‘ethic of purity’. The ethic of compassion consists in accepting another and recognising the dignity of another based on shared humanity. It is a frame of mind that combines moral intention with the emotions of empathy and sympathy. In contrast, the ethic of purity privileges adherence to the moral order of the group over considerations for the person. The ‘compassionate’ frame of mind weakens boundaries, while the ‘pure’ frame of mind reinforces them. The boundaries of a community result from the interplay of the two ethics. 相似文献
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Gian Vittorio Caprara Guido Alessandri Maria Giovanna Caprara 《Asian Journal of Social Psychology》2019,22(2):146-150
In our response, we aim to further contribute to the ongoing discussion of the construct of positivity and of the related research. We believe that each of the three commentaries has something unique to offer to the literature. By this response we take the opportunity to discuss the ideas that they present, and to illustrate some additional thoughts about positivity and its relationships with germane psychological constructs. 相似文献