Neural coding of reward magnitude in the orbitofrontal cortex of the rat during a five-odor olfactory discrimination task

The orbitofrontal cortex (OBFc) has been suggested to code the motivational value of environmental stimuli and to use this information for the flexible guidance of goal-directed behavior. To examine whether information regarding reward prediction is quantitatively represented in the rat OBFc, neural activity was recorded during an olfactory discrimination “go”/“no-go” task in which five different odor stimuli were predictive for various amounts of reward or an aversive reinforcer. Neural correlates related to both actual and expected reward magnitude were observed. Responses related to reward expectation occurred during the execution of the behavioral response toward the reward site and within a waiting period prior to reinforcement delivery. About one-half of these neurons demonstrated differential firing toward the different reward sizes. These data provide new and strong evidence that reward expectancy, regardless of reward magnitude, is coded by neurons of the rat OBFc, and are indicative for representation of quantitative information concerning expected reward. Moreover, neural correlates of reward expectancy appear to be distributed across both motor and nonmotor phases of the task.     

T1 difficulty and the attentional blink: expectancy versus backward masking

According to bottleneck models of the attentional blink (AB), first-target (T1) processing difficulty should be related to AB magnitude. Tests of this prediction that have varied T1 difficulty in the context of a standard AB paradigm, however, have yielded mixed results. The present work examines two factors that may mediate the relationship between T1 difficulty and the AB: observer expectancy and backward masking of T1. In two experiments, omission of the backward mask consistently yielded the predicted relationship between T1 difficulty and the AB. In contrast, observer expectancy influenced target identification accuracy but did not mediate the relationship between T1 difficulty and the AB.     

The effects of analytical and experiential rumination on autobiographical memory specificity in individuals with a history of major depression

This study examined the relationship between analytical rumination and autobiographical memory specificity in participants with a history of depression. Participants completed the autobiographical memory test twice, once before and once after an 8 min manipulation designed to increase either an abstract/analytical or concrete/experiential mode of information processing. Results indicated a significant three-way time (pre, post)×manipulation (analytical, experiential)×depressive rumination (high, low) interaction. This interaction was the result of a significant decline in memory specificity from pre- to post-manipulation in individuals reporting high levels of rumination about symptoms when depressed who were allocated to the analytical condition. The findings of this study extend previous work, suggesting that low memory specificity in formerly depressed patients may be a function of state levels of analytical self-focus, with this cognitive style being more easily reinstated in the recovery phase in those who report a greater trait tendency to ruminate about symptoms when low in mood.     

People as intuitive prosecutors: The impact of social-control goals on attributions of responsibility

Three experiments explored determinants of punitive character attributions to norm violators. Experiment 1 showed that ideological conservatism and manipulated threat to society increased anger and attributional punitiveness when there was ambiguity about culpability. Experiment 2 showed that informing observers that norm violations were widespread and rarely punished increased attributional punitiveness by activating anger-charged retributive goals. Experiment 3 showed that liberals and conservatives alike felt justified in assigning greater blame to high-status perpetrators who commit acts of negligence with more severe consequences but that only conservatives felt justified in doing so for low-status perpetrators. Overall, the results reinforce the hypothesis that societal threat activates a prosecutorial mindset identifiable by a correlated cluster of attributions, emotions, punishment goals and punitiveness.     

The Interpretability Logic of all Reasonable Arithmetical Theories

This paper is a presentation of astatus quæstionis, to wit of the problemof the interpretability logic of all reasonablearithmetical theories.We present both the arithmetical side and themodal side of the question.Dedicated to Dick de Jongh on the occasion of his 60th birthday     

Empirical Support for an Evolutionary Model of Self‐Destructive Motivation

We tested predictions generated from an evolutionary account of self‐destructive motivation in two survey studies of 18–24‐year‐old university students. As hypothesized, hierarchical regressions showed that the positive relationship between perceived burden to family and suicide ideation was amplified for participants with low measured health and romantic relationship satisfaction, and for participants with relatively young mothers. The moderating effect of maternal age was also observed in logistic regressions of suicide attempts. These effects occurred independently of depression, hopelessness, and other relevant extraneous variables. Results have implications for understanding self‐destructive motivation, assessing suicide risk, and preventing suicidal thinking and behavior.     

当今医学科技的发展趋势及我国的发展战略

作为生命科学最重要组成部分的医学科学走向科技发展的新时代。在下个世纪,科研重点将向生命科学和生命医学转移。充分认识医学科学技术的地位和作用,及当代医学科技发展的主要趋势和特点,制定我国医学科学的发展战略,加强医学高技术的发展,对我国的医学科技发展将具有十分重要的意义。     

The psychology of voting action on the psychological origins of electoral research, 1939–1964

This article examines the development of psychologically oriented voting behavior research between 1939–1964. It intends to show the psychological basis of the Columbia and Michigan approaches and its implications for the analysis of electoral behavior. It is argued that, in spite of the large differences commonly perceived between these two approaches, there is much similarity between them, both with regard to their psychological roots as to their principal conclusions.