BRCA1 testing and informed consent in a woman with mild retardation

Cancer predisposition testing can pose complex genetic counseling issues. This casereport discusses whether it is appropriate to provide BRCA1 testing to a woman withlimited intellectual capacity and documented psychological distress. This case is one ofseveral cancer counseling cases presented to our Genetic Counseling Supervision Groupover the past three and a half years. The Supervision Group provided valuable feedback and supportto proceed with this challenging case.     

Dysexecutive syndrome in Parkinson’s disease: the GREFEX study

The objectives of this study were to characterize the frequencies and profiles of behavioral and cognitive dysexecutive syndromes in PD (based on validated battery and diagnostic criteria) and to develop a shortened diagnostic battery. Eighty-eight non-demented patients with a diagnosis of PD were examined with an executive validated battery. Using a validated framework, the patients’ test results were interpreted with respect to normative data from 780 controls. A dysexecutive syndrome was observed in 80.6% of the patients [95% confidence interval: 71.1–90.1]. The dysexecutive profile was characterized by prominent impairments in deduction, flexibility, inhibition and initiation in the cognitive domain, and by global hypoactivity with apathy and hyperactivity in the behavioral domain. This finding implies that patients with PD should be assessed with cognitive tests and a validated inventory for behavioral dysexecutive syndromes. A shortened battery (based on three cognitive tests and three behavioral domains) provided high diagnostic accuracy.     

Lack of flexibility in visual grouping in patients with schizophrenia

The study attempted to distinguish automatic grouping processes from top-down processes in a visual perceptual task in 30 patients with schizophrenia and 30 matched controls. Participants decided whether 7 figures were all different or whether 2 adjacent figures were identical. The distance between figures was manipulated to produce 3 separated pairs of figures, the targets belonging to either the same pair (within-group trials) or different pairs (between-groups trials). As controls, patients benefited from proximity for grouping. Top-down processes were explored by manipulating the proportion of within-group and between-groups trials in 3 experimental blocks. In patients, response times (RTs) decreased for within-group trials when within-group trials were more frequent, indicating that performance was correctly adapted to the type of block. Unlike controls, however, this RT decrease was not accompanied by a cost for between-groups trials. Ocular movement recordings revealed that controls were able to focus on between-groups regions selectively when between-groups trials were more frequent, whereas patients were unable to do so. The authors suggest that top-down processes allowing the construction of a selective representation of between-groups regions are impaired in patients with schizophrenia.     

DNA-sequence patenting: National Society of Genetic Counselors (NSGC) position paper

In November 2000, the Genetic Services Committee of the National Society of Genetic Counselors (NSGC) convened a working group to draft a position paper on patenting of DNA-sequences. The mandate of the group was to produce general position statements that support the perspective and needs of consumers of DNA-based genetic tests and therapies (our patients and their families) and participants in DNA-based genetic research. After review and discussion of the literature on DNA-sequence patenting issues, the working group drafted position statement points that support current United States Patent and Trademark Office (USPTO) guidelines; broad licensing of DNA-sequence patents; nonenforcement of DNA-sequence patents in noncommercial research; reasonable royalty rates; an informed consent process for research participants that discloses whether they can share in any financial rewards relating to the project; the development of guidelines for licensing of DNA-sequence patents; and the establishment of oversight organizations to monitor licensing of DNA-sequence patents. These position statements were approved by the NSGC Board of Directors in the fall of 2001.     

Phases of Group Development: A View from Self Psychology

This paper delineates four phases of group development from the standpoint of self psychological theory. The author contends that a stable sense of groupself develops over time and that the groupself has a distinct number of phases, each of which has a therapeutic impact on members. The individual patient's selfobject experiences include a relationship to the group-as-a-whole, a transference state of which the leader is but one part. Thus, rather than dilute the transference, group analysis offers a unique opportunity to help the individual experience him or herself within a selfobject matrix that extends beyond the dyad. Group analysis leads to a strengthening of the self, especially as it enables the self to experience itself as part of a group identity, which provides alter-ego selfobject experiences, as well as a sense of acceptance within a larger community. This paper attempts to clarify how different selfobject experiences may be highlighted within the groupself at different stages of group development.     

Validation,Persuasion and Recycling: Capitalizing on the Social Ecology of Newspaper Use

Two experiments used clinical validation to increase scrutiny of messages posted in public settings. The first experiment used a 2 (validation: no/yes) × 2 (persuasion: none/"it is important") factorial design to develop messages about newspaper recycling. The prompt (no validation/no persuasion) had little impact on newspaper recycling, but the other 3 signs all resulted in increased recycling while the signs were in place. After signs were removed, recycling remained significantly higher than baseline (marginally significant for validation/persuasion). At the end of the study, number of cognitions favoring recycling was significantly higher in the validation-only condition and was lower in the validation/persuasion condition. Experiment 2 tested whether signs would have more impact if they were sensitive to the social ecology of newspaper recycling; that is, readers' tendency to leave newspapers behind so others may read them. Messages based on a 2 (message: validation-only/validation plus persuasion) × 2 (ecology: no social ecology/social ecology) factorial design supported social ecology's importance. Furthermore, because of the increased sharing in the social ecology conditions, total numbers of newspapers used was significantly lower in those buildings. Validation only yielded sustained behavior change in both Experiments 1 and 2, supporting additional research on the question of whether validation can, by itself, lead to cognitive elaboration and self-persuasion.     

Pleasant emotional induction broadens the visual world of young children

These experiments aimed at studying the influence of emotional context on global/local visual processing in children. Children 5 years old, known to present an immature global visual bias, and 8 years old, known to pay attention predominantly to global information, were placed in either a neutral or pleasant emotional context and subsequently presented with a global/local visual judgement task. As with previous findings for adults, both age groups presented a pronounced perceptual bias toward global information following exposure to emotionally pleasant pictures. Interestingly, younger children, who do not present a global bias during the neutral exposure, presented the same preference for global information as older children when exposed to the pleasant context. These findings indicate that emotion may strongly affect visual perception in children, with important implications for educational practice and models of cognition.     

Culture of honour theory and social anxiety: Cross-regional and sex differences in relationships among honour-concerns,social anxiety and reactive aggression

According to the Appraisal-Tendency Framework (Han, Lerner, & Keltner, 2007), certainty-associated emotions increase risk taking compared with uncertainty-associated emotions. To date, this general effect has only been shown in static judgement and decision-making paradigms; therefore, the present study tested the effect of certainty on risk taking in a sequential decision-making task. We hypothesised that the effect would be reversed due to the kind of processing involved, as certainty is considered to encourage heuristic processing that takes into account the emotional cues arising from previous decisions, whereas uncertainty leads to more systematic processing. One hundred and one female participants were induced to feel one of three emotions (film clips) before performing a decision-making task involving risk (Game of Dice Task; Brand et al., 2005). As expected, the angry and happy participants (certainty-associated emotions) were more likely than the fearful participants (uncertainty-associated emotion) to make safe decisions (vs. risky decisions).     

Psychological Predictors of Career Planning among Active Elite Athletes: An Application of the Social Cognitive Career Theory

The present study examines mechanisms underlying career planning among athletes in the context of sport career termination. The contribution of conscientiousness to athletes' career planning was investigated among 180 active athletes (88 females, 92 males; M_age = 20.36) by applying the social cognitive career theory (SCCT). Bootstrap analyses, performed at both broad and facet-level, revealed that conscientious individuals are more likely to plan for their future career because they set higher goals and are more confident in their capacity to plan their future career. Implications for practice are discussed in relation to intervention that could induce career planning among athletes.     

Level of emotional awareness in the general French population: Effects of gender,age, and education level

The Levels of Emotional Awareness Scale (LEAS) developed by Lane et al. ( 1990 1990) measures the ability of a subject to discriminate his or her own emotional state and that of others. The scale is based on a cognitive‐developmental model in which emotional awareness increases in a similar fashion to intellectual functions. Because studies performed using North American and German populations have demonstrated an effect of age, gender, and level of education on the ability to differentiate emotional states, our study attempts to evaluate whether these factors have the same effects in a general French population. 750 volunteers (506 female, 244 male), who were recruited from three regions of France (Lille, Montpellier, Paris), completed the LEAS. The sample was divided into five age groups and three education levels. The results of the LEAS scores for self and others and the total score showed a difference in the level of emotional awareness for different age groups, by gender and education level. A higher emotional level was observed for younger age groups, suggesting that emotional awareness depends on the cultural context and generational societal teachings. Additionally, the level of emotional awareness was higher in women than in men and lower in individuals with less education. This result might be explained by an educational bias linked to gender and higher education whereby expressive ability is reinforced. In addition, given the high degree of variability in previously observed scores in the French population, we propose a standard based on our French sample.