Attentional requirements for object-location priming

The purpose of the present experiments was to investigate whether a verbal and a spatial secondary task would disrupt priming for object-location associations. Symbols were placed one at a time in one of nine locations in a rectangle. Implicit memory was tested with a reaction time (RT) task. All symbols were placed in the same location of the rectangle across 10 trial blocks; then, all their locations were changed. Responses were made on the numeric keypad, which corresponded to the spatial locations used in the rectangle. A decrease in RTs across the first 10 trial blocks followed by an increase in RTs when the symbols changed locations would indicate priming for the associations. The results were that implicit memory for object-location associations was obtained under single-, but not under dual-task conditions. We have interpreted the results in terms of a working memory model that posits that implicit memory will suffer when cognitive resources are limited.     

Small on the left,large on the right: numbers orient visual attention onto space in preverbal infants

Numbers are represented as ordered magnitudes along a spatially oriented number line. While culture and formal education modulate the direction of this number–space mapping, it is a matter of debate whether its emergence is entirely driven by cultural experience. By registering 8–9‐month‐old infants’ eye movements, this study shows that numerical cues are critical in orienting infants’ visual attention towards a peripheral region of space that is congruent with the number's relative position on a left‐to‐right oriented representational continuum. This finding provides the first direct evidence that, in humans, the association between numbers and oriented spatial codes occurs before the acquisition of symbols or exposure to formal education, suggesting that the number line is not merely a product of human invention.     

Memory traces compete under regimes of limited Arc protein synthesis: Implications for memory interference

Recently encoded information can be lost in the presence of new information, a process called 'retrograde interference'. Retrograde interference has been extensively described for more than a century; however, little is known about its underlying mechanisms. Different approaches agree on the need of the synthesis of plasticity related proteins (PRPs) to consolidate a long-term memory (LTM). Our hypothesis is that when PRPs are limited, interference of a task over LTM formation of another may be due to the utilization of protein resources common to both tasks. Here, by combining the tasks of inhibitory avoidance (IA) and open field (OF) exploration in rats, we show that memory traces compete for their stabilization if PRPs are limited. As a result, LTM is formed for only one of the tasks with a consequent decrease in the memory for the other. Furthermore, infusing Arc antisense oligonucleotide into the dorsal hippocampus, we found that Arc is necessary for LTM formation of these two types of learning tasks and is one of the PRPs that can be shared between them when animals are trained in both OF and IA. In sum, these findings suggest that under conditions of reduced protein availability, a learning task interferes with LTM formation of another by using the available PRPs.     

The early development of human mirror mechanisms: evidence from electromyographic recordings at 3 and 6 months

In primates and adult humans direct understanding of others' action is provided by mirror mechanisms matching action observation and action execution (e.g. Casile, Caggiano & Ferrari, 2011). Despite the growing body of evidence detailing the existence of these mechanisms in the adult human brain, their origins and early development are largely unknown. In this study, for the first time, electromyographic (EMG) measures were used to shed light on the emergence of mirror motor mechanisms in infancy. EMG activity was recorded while 6‐ and 3‐month‐old infants watched two videos displaying an agent reaching for, grasping and bringing an object either to the mouth or to the head. Results indicate that the motor system of 6‐month‐olds, but not 3‐month‐olds, was recruited and selectively modulated during observation of the goal‐directed actions, favoring the idea that mirror mechanisms driving action understanding gradually emerge during early development.     

The neural correlates of processing newborn and adult faces in 3‐year‐old children

The current study examines the processing of upright and inverted faces in 3‐year‐old children (n = 35). Event‐related potentials (ERPs) were recorded during a passive looking paradigm including adult and newborn face stimuli. We observed three face‐sensitive components, the P1, the N170 and the P400. Inverted faces elicited shorter P1 latency and larger P400 amplitude. P1 and N170 amplitudes were larger for adult faces. To examine the role of experience in the development of face processing, the processing of adult and newborn faces was compared for children with a younger sibling (n = 23) and children without a younger sibling (n = 12). Age of sibling at test correlated negatively with P1 amplitude for adult and newborn faces. This may indicate more efficient processing of different face ages in children with a younger sibling and potentially reflects a more flexible face representation.     

The standard ontological framework of cognitive neuroscience: Some lessons from Broca’s area

Since cognitive neuroscience aims at giving an integrated account of mind and brain, its ontology should include both neural and cognitive entities and specify their relations. According to what we call the standard ontological framework of cognitive neuroscience (SOFCN), the aim of cognitive neuroscience should be to establish one-to-one mappings between neural and cognitive entities. Where such entities do not yet closely align, this can be achieved by reforming the cognitive ontology, the neural ontology, or both. In order to assess the limits and the possibilities of the SOFCN, we will examine a paradigmatic case study: the concept of Broca’s area, which indicates an alleged mapping between the left inferofrontal gyrus and the production of language. We review evidence showing that such a mapping does not hold, thus calling into question either the status of Broca’s area or the validity of the SOFCN. We then propose some strategies for addressing the issue and suggest that it may be solved within the SOFCN by adopting both of the following strategies: first, more accurately defining the relevant neural structures and second, switching the focus of neural ontology from structures to events, individuated by a where (neural structures) conjoint with a how (oscillatiory frequency).     

The Moderating Effect of Within‐Group Similarity on Change in a Strengths‐Based Programme for Incarcerated Young Men

Many youth who are incarcerated within juvenile correctional facilities experience mental health disorders, histories of victimization and suicide ideation. Strengths‐based intervention programmes are intended to enhance participants' resilience against such challenges. However, little is known about how the composition of intervention groups contributes to programmes' efficacy. This study addresses the impact of within‐group similarity on the success of a strengths‐based intervention for incarcerated young men (n = 141). Similarity was assessed in terms of self‐reported demographics and behaviours and belief systems. Youths' masculine ideology, caring and cooperative behaviours, ethnic pride and respect for differences, self‐efficacy regarding education and non‐violence, and attitudes about criminal behaviour were measured before and after intervention. Results indicate that participants' caring and cooperative behaviour increased during the intervention. However, their education‐related self‐efficacy was reduced, and the perceived benefits of criminal activity increased. These changes were moderated by group composition: less similarity between participants and their group members was associated with less negative change. In the context of juvenile corrections facilities, where staying the same may be a relatively positive outcome, perhaps the more relevant question is not which processes and characteristics of others better enable youth to change but which experiences help them retain positive aspects of themselves. Copyright © 2014 John Wiley & Sons, Ltd.     

Dopaminergic and cholinergic modulations of visual-spatial attention and working memory: insights from molecular genetic research and implications for adult cognitive development

Attention and working memory are fundamental for selecting and maintaining behaviorally relevant information. Not only do both processes closely intertwine at the cognitive level, but they implicate similar functional brain circuitries, namely the frontoparietal and the frontostriatal networks, which are innervated by cholinergic and dopaminergic pathways. Here we review the literature on cholinergic and dopaminergic modulations of visual-spatial attention and visual working memory processes to gain insights on aging-related changes in these processes. Some extant findings have suggested that the cholinergic system plays a role in the orienting of attention to enable the detection and discrimination of visual information, whereas the dopaminergic system has mainly been associated with working memory processes such as updating and stabilizing representations. However, since visual-spatial attention and working memory processes are not fully dissociable, there is also evidence of interacting cholinergic and dopaminergic modulations of both processes. We further review gene-cognition association studies that have shown that individual differences in visual-spatial attention and visual working memory are associated with acetylcholine- and dopamine-relevant genes. The efficiency of these 2 transmitter systems declines substantially during healthy aging. These declines, in part, contribute to age-related deficits in attention and working memory functions. We report novel data showing an effect of dopamine COMT gene on spatial updating processes in older but not in younger adults, indicating potential magnification of genetic effects in old age.     

No own-age bias in 3-year-old children: More evidence for the role of early experience in building face-processing biases

This study aimed to investigate the presence of an own-age bias in young children who accumulated different amounts of early experience with child faces. Discrimination abilities for upright and inverted adult and child faces were tested using a delayed two-alternative, forced-choice matching-to-sample task in two groups of 3-year-old children, one composed of first-born children and the other composed of children who, from the time of their birth, had daily exposure to a child face through the presence of an older sibling in their home. Children without an older sibling were better at differentiating among adult faces than among child faces and showed an inversion effect that was selective for adult faces. Children with an older sibling were equally skilled at differentiating upright adult and child faces and showed inversion effects of comparable magnitude for both face types. Results support the notion that face representational space of younger children is tuned to adult faces and suggest that age biases during early childhood are dependent on the effects of early experience.