Error monitoring dysfunction across the illness course of schizophrenia

Response monitoring abnormalities have been reported in chronic schizophrenia patients, but it is unknown whether they predate the onset of psychosis, are present in early stages of illness, or are late-developing abnormalities associated with illness progression. Response-synchronized event-related potentials (ERP) recorded during a picture-word matching task yielded error-related negativity (ERN), correct-response negativity (CRN), and error positivity (Pe) from 84 schizophrenia patients (SZ), 48 clinical high risk patients (CHR), and their age-matched healthy controls (HC; n = 110 and 88, respectively). A sub-sample of 35 early illness schizophrenia patients (ESZ) was compared to 93 age-matched HC and the CHR patients (after statistically removing the effects of normal aging). Relative to HC, 1) SZ, ESZ, and CHR had smaller ERNs, and 2) SZ and ESZ had larger CRNs and smaller Pes. Within the SZ, longer illness duration was associated with larger CRNs but was unrelated to ERN or Pe. CHR and ESZ did not differ on ERN or CRN, although Pe was smaller in ESZ than CHR. These results indicate that while ERN, CRN, and Pe abnormalities are present early in the illness, only the ERN abnormality is evident prior to psychosis onset, and only the CRN abnormality appears to worsen progressively over the illness course. Brain regions subserving response monitoring may be compromised early in the illness and possibly during its clinical prodrome.     

An IRT analysis of motive questionnaires: The Unified Motive Scales

Multiple inventories claiming to assess the same explicit motive (achievement, power, or affiliation) show only mediocre convergent validity. In three studies (N = 1685) the structure, nomological net, and content coverage of multiple existing motive scales was investigated with exploratory factor analyses. The analyses revealed four approach factors (achievement, power, affiliation, and intimacy) and a general avoidance factor with a facet structure. New scales (the Unified Motive Scales; UMS) were developed using IRT, reflecting these underlying dimensions. In comparison to existing questionnaires, the UMS have the highest measurement precision and provide short (six-item) and ultra-short (three-item) scales. In a fourth study (N = 96), the UMS demonstrated incremental validity over existing motive scales with respect to several outcome criteria.     

Performing well - Feeling bad? Effects of perfectionism under experimentally induced stress on tension and performance

The present study explored the influence of dispositional perfectionism (i.e. perfectionistic concerns and perfectionistic strivings) on tension and performance under low or high experimentally induced stress. Results support the moderating role of perfectionism concerning tension and indicate that stress-related processes underlie the vulnerability of perfectionistic concerns. In addition, buffering effects of perfectionistic strivings were found, supporting the 2 × 2 model of dispositional perfectionism by Gaudreau and Thompson (2010). No evidence was found for the moderating role of perfectionistic strivings concerning performance, but results provide evidence for positive effects of perfectionistic concerns on performance.     

Effects of speed of word processing on semantic access: the case of bilingualism

Bilingual speakers generally manifest slower word recognition than monolinguals. We investigated the consequences of the word processing speed on semantic access in bilinguals. The paradigm involved a stream of English words and pseudowords presented in succession at a constant rate. English-Welsh bilinguals and English monolinguals were asked to count the number of letters in pseudowords and actively disregard words. They were not explicitly told that pairs of words in immediate succession were embedded and could either be semantically related or not. We expected that slower word processing in bilinguals would result in semantic access indexed by semantic priming. As expected, bilinguals showed significant semantic priming, indexed by an N400 modulation, whilst monolinguals did not. Moreover, bilinguals were slower in performing the task. The results suggest that bilinguals cannot discriminate between pseudowords and words without accessing semantic information whereas monolinguals can dismiss English words on the basis of subsemantic information.     

BIS and BAS correlates with psychophysiological and cortical response systems during aversive and appetitive emotional stimuli processing

The present research intended first to confirm psychophysiological and cortical responses to valence- and arousal-manipulated stimuli and second to show how the BIS and BAS (Behavioural Inhibition and Activation System) personality characteristics correlated with these psychophysiological and cortical responses. Multiple measures were recorded, such as psychophysiological (skin conductance response, heart rate, and electromyography) and ERPs (event-related potentials) responses, during viewing IAPS figures, that varied in terms of pleasantness (appetitive vs. aversive) and arousing power (high vs. low intensity). Autonomic variables and two ERP positive deflections (P3 and LPP ERP effects) were found to be modulated by valence and arousal rating, with an increased response for high arousing and negative or positive stimuli in comparison with low arousing and neutral stimuli. Moreover, high BAS subjects were more responsive to positive than negative emotions, whereas high BIS subjects responded in greater measure to negative and arousing emotions. Findings were discussed in light of biphasic model of emotion comprehension.     

From racial discrimination to risky sex: prospective relations involving peers and parents

This study investigated how early experience with racial discrimination affected the subsequent risky sexual behaviors of a diverse sample of African American youths (N = 745). The analyses focused on 3 risk-promoting factors thought to mediate the hypothesized discrimination → risky sex relation: negative affect, affiliation with deviant peers, and favorable attitudes toward risky sex. In addition, attentive parenting was examined as a protective factor. Analyses using structural equation modeling revealed that youths who perceived more racial discrimination at age 10 or 11 were engaging in more sexual risk taking at age 18 or 19. This relation was mediated by the hypothesized risk-promoting factors via pathways that were consistent with our conceptual model. Results also indicated a prospective reciprocal relation between parenting and children's deviant affiliations: deviant peer affiliations at age 10 or 11 predicted more attentive parenting behaviors by the parents; this response from the parents, in turn, predicted relatively fewer deviant affiliations when the youths were 15 or 16. Study findings are discussed in terms of their relevance to the disproportionately high rates of sexually transmitted infections among African Americans.     

Lexical and sublexical semantic preview benefits in Chinese reading

Semantic processing from parafoveal words is an elusive phenomenon in alphabetic languages, but it has been demonstrated only for a restricted set of noncompound Chinese characters. Using the gaze-contingent boundary paradigm, this experiment examined whether parafoveal lexical and sublexical semantic information was extracted from compound preview characters. Results generalized parafoveal semantic processing to this representative set of Chinese characters and extended the parafoveal processing to radical (sublexical) level semantic information extraction. Implications for notions of parafoveal information extraction during Chinese reading are discussed.     

Implicit Science Stereotypes Mediate the Relationship between Gender and Academic Participation

While the gender gap in mathematics and science has narrowed, men pursue these fields at a higher rate than women. In this study, 165 men and women at a university in the northeastern United States completed implicit and explicit measures of science stereotypes (association between male and science, relative to female and humanities), and gender identity (association between the concept “self” and one’s own gender, relative to the concept “other” and the other gender), and reported plans to pursue science-oriented and humanities-oriented academic programs and careers. Although men were more likely than women to plan to pursue science, this gap in students’ intentions was completely accounted for by implicit stereotypes. Moreover, implicit gender identity moderated the relationship between women’s stereotypes and their academic plans, such that implicit stereotypes only predicted plans for women who strongly implicitly identified as female. These findings illustrate how an understanding of implicit cognitions can illuminate between-group disparities as well as within-group variability in science pursuit.     

Gray Matters: A Deployed Physician’s Perspective on Combat Medicine in Iraq

A female physician who was serving as a first-year medicine resident in Manhattan in September 2001 writes this paper. It details her experience of signing up for military service as a result of the September 11th attack on the United States. She lays out the surroundings, atmosphere, and reactions of those around her during the attack and details her own personal motivations for joining the military, her need to take control and help those in need heal while also trying to heal herself. Grateful, yet haunted by her experience, she provides an intimate glimpse into her time serving as a combat physician at a trauma hospital in Balad, Iraq during the 2007 military surge. A trained geriatrician and palliative care physician she recounts the stories of several patients that have forever shaped her life and explores the contradictions and ethical challenges she faced while caring for them ultimately struggling with the uncertainty of whether what she was truly doing was good for those she served or herself.     

Examination of the Psychometric Properties of the Spiritual Fitness Assessment

Using a sample of 196 undergraduate students, the present study investigated the psychometric properties of the Spiritual Fitness Assessment, a measure of spiritual fitness designed for use by health and fitness professionals. Examination of inter-item consistency produced satisfactory alpha coefficients for the total test and its three subscales. Correlations of the SFA with measures of spirituality and spiritual well-being provide support for convergent validity. Significant positive correlations with a measure of self-esteem suggest that the test has satisfactory criterion validity. Correlations with age, sex, and a measure of social desirability indicate that the SFA is significantly, though only moderately, affected by demographic variables and motivated response tendencies. Factor analysis of the SFA items indicate that the test is factorially complex and subscales may need to be refined to better measure their intended constructs. Overall, the results of the study suggest that the test may be useful for evaluations of spiritual fitness. Further research with samples drawn from different populations is needed on the test to better establish its reliability and validity.