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171.
Agatha M. Gallo Diana J. Wilkie Yingwei Yao Robert E. Molokie Christiane Stahl Patricia E. Hershberger Zhongsheng Zhao Marie L. Suarez Bonnye Johnson Rigoberto Angulo Jesus Carrasco Veronica Angulo Alexis A. Thompson 《Journal of genetic counseling》2016,25(2):325-336
Interventions to assist reproductive health decision-making in populations affected by sickle cell disease (SCD) or trait (SCT) lack proven efficacy over time. Our aim was to compare effects of CHOICES, a Web-based multimedia education program on implementing informed reproductive plans, and usual care education (e-Book) on reproductive knowledge, intention, and behavior over 24 months. We randomized 234 participants with SCD (n?=?138) or SCT (n?=?96) (age 18–35 years, 35 % male, 94 % African American) to CHOICES and e-Book groups. Participants completed a sickle cell-specific reproductive measure before and four times after the intervention (6, 12, 18 and 24 months). Compared to the e-Book group the CHOICES group had significantly more improvement in knowledge over time (p?=?.004) but not intention (p?=?.18) or behavior (p?=?.69). At baseline, 114 (48.7 %) participants reported having partners who would not put the couple at risk for their children inheriting SCD. Of the 116 (49.6 %) at-risk participants, a higher poroportion of those who were in the CHOICES group chose partners that reduced their risk by the last visit than the e-Book group (p?=?.04). Study findings provide important insights for designing a national trial of the CHOICES intervention focusing on subjects whose partner status puts them at risk for having a child with SCD. 相似文献
172.
Bettina Meiser Ben Storey Veronica Quinn Belinda Rahman Lesley Andrews 《Journal of genetic counseling》2016,25(2):218-227
Next generation sequencing (NGS) for patients at risk of hereditary cancer syndromes can also identify non-cancer related mutations, as well as variants of unknown significance. This study aimed to determine what benefits and shortcomings patients perceive in relation to NGS, as well as their interest and information preferences in regards to such testing. Eligible patients had previously received inconclusive results from clinical mutation testing for cancer susceptibility. Semi-structured telephone interviews were subjected to qualitative analysis guided by the approach developed by Miles and Huberman. The majority of the 19 participants reported they would be interested in panel/genomic testing. Advantages identified included that it would enable better preparation and allow implementation of individualized preventative strategies, with few disadvantages mentioned. Almost all participants said they would want all results, not just those related to their previous diagnosis. Participants felt that a face-to-face discussion supplemented by an information booklet would be the best way to convey information and achieve informed consent. All participants wanted their information stored and reviewed in accordance with new developments. Although the findings indicate strong interest among these individuals, it seems that the consent process, and the interpretation and communication of results will be areas that will require revision to meet the needs of patients. 相似文献
173.
Jessica J. Cameron Danu Anthony Stinson Lisa Hoplock Christine Hole Jodi Schellenberg 《Self and identity》2016,15(5):561-578
People use impressions of an evaluative target’s self-esteem to infer their possession of socially desirable traits. But will people still use this self-esteem proxy when trait-relevant diagnostic information is available? We test this possibility in two experiments: participants learn that a target person has low or high self-esteem, and then receive diagnostic information about the target’s academic success or failure and positive or negative affectivity (Study 1), or watch a video of the target’s extraverted or introverted behavior (Study 2). In both experiments, participants’ impressions of the target’s traits accurately tracked diagnostic information, but impressions also revealed an independent self-esteem proxy effect. Evidently, the self-esteem proxy is robust and influences person perception even in the presence of vivid individuating information. 相似文献
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Harry M. Grant Lane C. Bredahl John Clay Jennifer Ferrie Jane E. Groves Timothy A. McDorman Veronica J. Dark 《Applied cognitive psychology》1998,12(6):617-623
Context-dependency effects on memory for lists of unrelated words have been shown more often with recall than with recognition. Context dependency for meaningful text material was examined using two standard academic testing techniques: short answer (recall) and multiple choice (recognition). Forty participants read an article in either silent or noisy conditions; their reading comprehension was assessed with both types of test under silent or noisy conditions. Both tests showed context-dependency effects in which performance was better in the matching conditions (silent study/silent test and noisy study/noisy test) than in the mismatching conditions (silent study/noisy test and noisy study/silent test). Context cues appear to be important in the retrieval of newly learned meaningful information. An academic application is that students may perform better on exams by studying in silence. Copyright © 1998 John Wiley & Sons, Ltd. 相似文献
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Two studies examined the relationship of sex of subject, sex-typing of tasks, and prior task experience on self-confidence ratings of Black men and women. In both investigations, women's self-confidence tended to vary as a function of task type, while men's self-confidence remained relatively stable across all tasks. Prior experience with the task was highly correlated with self-confidence ratings for men and women and moderated the effects. The variations in the findings of Studies I and II and implications for future research are discussed.Portions of this study were reported at the Eastern Psychological Association Convention, 1983. 相似文献
180.
The psychological condition of people surviving by dialysis has been investigated using the Dialysis Problem Check-list together with appropriate ratings. Although there may have been some underestimation owing to a denial effect, many stressing difficulties were revealed amongst a sample of dialysis patients and their partners. Some difficulties were associated with hardships directly caused by renal failure and the dialysis techniques, but others had their origin in the practices of the staff, particularly in relation to training and communications. The implications in terms of psychological intervention within a kidney unit are discussed. 相似文献