Psychological factors and use of antiepileptic drugs: pilot work using an objective measure of adherence

Given the current emphasis on the "concordance" prescribing model, a study was designed to determine the influence of patients' beliefs about epilepsy, beliefs about medication and a range of neuroepilepsy variables on drug adherence among a sample of epilepsy patients. A special feature of the study was the use of a credible objective measure of drug adherence. Psychological health was also assessed. Thirty-seven patients were recruited from a local epilepsy clinic. Beliefs about epilepsy (illness representations), beliefs about epilepsy medication, anxiety, depression, neuroepilepsy status and adherence were all measured. Data were collected via clinical interview and questionnaire methods. Adherence with drug treatment was determined by an objective measure using low-dose phenobarbital as an indicator of adherence and, or, measurement of antiepileptic drug levels. Neither illness representations nor beliefs about epilepsy drugs were related to adherence. With the exception of time since last seizure, which was positively related to adherence, neuroepilepsy variables were unrelated to adherence. A number of significant associations between cognitive representations of epilepsy and mood were found.     

Linking goal self-concordance and affective reactions to goal conflict

Most people would agree that facing goal conflict is a negative experience. However, many, but not all empirical studies actually show a negative relationship between goal conflicts and well-being: goal conflicts apparently differ in their effects. The aim of the present study was to investigate the role of the level of goal self-concordance (i.e., to what extent goals are pursued with self-determined motivation) for people’s affective reactions to goal conflicts due to resource constraints. Analyses of goal conflicts experienced at work by N = 647 junior scientists shed light onto the role of levels of self-concordance of the conflicting goals on the way the goal conflict is experienced. Results show that goal self-concordance explains variance in affective reaction beyond goal importance and goal attainability. More specifically, conflicts between two goals with high levels of self-concordance are associated to rather positive affect (e.g., excited). In contrast, conflicts between two goals with low levels of self-concordance are associated to rather negative affect (e.g., frustrated). Overall, these results emphasize the need to consider goal properties in future research on goal conflicts.     

Acceptance in Cognitive Behavioral Psychotherapies: Different or the Same?

Acceptance is a key construct in both rational emotive behavior therapy (REBT) and acceptance and commitment therapy (ACT). The objectives of this study were to assess and compare the properties of ACT acceptance with those of REBT acceptance in predicting emotions. A sample of 112 subjects, comprising different educational and occupational status, completed three measures of acceptance (REBT and ACT), two of mindfulness, as well as completing depression and anxiety scales. Both ACT acceptance as process and REBT acceptance could predict significant ACT acceptance as outcome. Mindfulness as a trait also predicted the level of ACT outcome acceptance as well as the level of REBT acceptance, but mindfulness as process predicted only ACT outcome acceptance. The results show that REBT acceptance, ACT acceptance and mindfulness can explain anxiety and depression in different ways. The results show that the difference between ACT acceptance and REBT acceptance primary concern the process of acceptance, most likely due to the underlying cognitive processing. The outcome acceptance and emotional level are similar in the two conditions. Future research should employ multiple cognitive measurements.     

Fokale psychodynamische Psychotherapie der Anorexia nervosa

The paper presents a manual for the focal psychodynamic psychotherapy of anorexia nervosa (AN). The manual was developed in the context of the largest randomized controlled trial of outpatient psychotherapy for AN so far [Anorexia Nervosa Treatment of OutPatients (ANTOP), n=234]. The study compares focal psychodynamic psychotherapy with cognitive-behavioral therapy and with a control group with free choice of therapy outside the study. The manual comprises instructions for the working through of typical focal emotional and interpersonal issues of AN. Also recommendations for anorexia-specific therapeutic difficulties in the course of treatment are given. First results concerning the efficacy of the therapies carried out based on the manual are expected after completion of the ANTOP study in the middle of the year 2010.     

Recognition and sex categorization of adults' and children's faces: examining performance in the absence of sex-stereotyped cues

The ability of children and adults to classify the sex of children's and adults' faces using only the biologically based internal facial structure was investigated. Face images of 7- to 10-year-old children and of adults in their 20s were edited digitally to eliminate hairstyle and clothing cues to sex. Seven-year-olds, nine-year-olds, and adults classified a subset of these faces by sex and were asked, subsequently, to recognize the faces from among the entire set of faces. This recognition task was designed to assess the relationship between categorization and recognition accuracy. Participants categorized the adult faces by sex at levels of accuracy varying from just above chance (7-year-olds) to nearly perfect (adults). All participant groups performed less accurately for children's faces than for adults' faces. The 7-year-olds were unable to classify the children's faces by sex at levels above chance. Finally, the faces of children and adults were equally recognizable--a finding that has theoretical implications for understanding the relationship between categorizing and identifying faces.     

On the other side of the mean: the perception of dissimilarity in human faces

We created a 'face space' using a laser-scan representation of faces. In this space, a caricature can be made by moving a face away from the average face, along the line connecting the particular face to the average face. Here, we move the face along this line in the other direction, proceeding through the mean and 'out the other side'. This results in a face that is 'opposite', in a computational sense, to the original face. We morphed several faces into their anti-faces and sampled the morph trajectory in five discrete steps. We then collected similarity ratings from human participants for all possible pairs of morphed faces to determine how the distances in the 'physical face space' related to the distances in the 'psychological face space'. The data indicate that there is a perceptual discontinuity of face identity as the face crosses over to the 'other side of the mean'. We consider these results in the context of face-space models of human face processing.     

Loneliness predicts suicidal ideation and anxiety symptoms in long-term childhood cancer survivors

Background/ObjectiveLong-term childhood cancer survivors (CCS) are at risk for adverse late effects. However, not all of them are well understood. The present study addressed loneliness, a previously under-researched mental health risk in cancer survivor populations. We assessed the prevalence of loneliness and its impact on psychological symptoms over time. Method: A registry-based sample of N = 633 adult long-term CCS underwent medical and psychological assessments and took part in a follow-up survey 2.5 years later. Psychological symptoms (somatic, anxiety, depression symptoms, and suicidal ideation) were measured using the Patient Health Questionnaire. We calculated linear regression models of symptoms at follow-up to investigate the impact of loneliness over time (controlling for symptoms at baseline and relevant confounders). Results: Loneliness was reported by 17.70% of CCS. In multivariate linear regression analyses, loneliness was still predictive of more severe anxiety symptoms and suicidal ideation over two years later. Loneliness did not predict somatic and depression symptoms at follow-up (which increased with age). Conclusions: Loneliness affected a significant number of CCS and was a risk factor for persistent anxiety symptoms and suicidal ideation. The extent to which young cancer patients’ re-integration into society is successful could thus have important implications for well-being in adulthood.     

Dietary patterns and intelligence in early and middle childhood

The association between intelligence and diet at 3.5 and 7 years was examined in 591 children of European descent. Approximately half of the children were born small-for-gestational age (birth weight ≤ 10th percentile). The relationship between IQ and diet (measured by food frequency) was investigated using multiple regression analyses. Eating margarine at least daily was associated with significantly lower IQ scores at 3.5 years in the total sample and at 7 years in SGA children. For all children, eating the recommended daily number of breads and cereals was associated with significantly higher IQ scores at 3.5 years, and those who ate fish at least weekly had significantly higher IQ scores at 7 years than those who did not. The consumption of fish, breads and cereals commeasurable with nutritional guidelines may be beneficial to children's cognitive development. In contrast, consuming margarine daily was associated with poorer cognitive functioning. Further research is needed to identify the nutrients that may underlie this association.