Dexamethasone Does Not Prevent Seven-Day ADX-Induced Apoptosis in the Dentate Gyrus of the Rat Hippocampus

Long-term adrenalectomy (ADX) is known to result in apoptosis within the dentate gyrus of the rat hippocampus. While the underlying mechanism is still unclear, adrenal steroids appear to play a pivotal role in granule cell survival, as administration of the mineralocorticoid receptor (MR) agonists, corticosterone and aldosterone, to ADX rats results in protection against the ADX-induced effect. The consequence of administration of the glucocorticoid receptor (GR) agonists, dexamethasone and RU28362, however, is less clear, and either complete or only partial protection for the ADX animal has been reported. This study investigated further the role played by GR in the degenerative process. After establishing the characteristics of seven-day ADX-induced apoptosis in the young male Wistar rat, the effect of chronically-implanted, subcutaneous pellets containing various doses of dexamethasone and corticosterone, on ADX-induced apoptosis was studied. Both high and low doses of corticosterone were found to be protective. In contrast to some other studies, however, neither dose of dexamethasone had any obvious protective effect and rather seemed to increase apoptosis in dentate gyrus of intact animals. Intracerebroventricular infusion of dexamethasone for seven days was also found to be ineffective in preventing apoptosis, demonstrating that it is occupation of MR, rather than GR, which is crucial to dentate gyrus granule cell survival.     

Programmed instruction: What it is and how to do it

Five behaviorological features of programmed instruction are outlined: behavioral objectives, reinforcement, activity rate: high and relevant, successive approximation, and mastery progression. Each of these topics is explained, and examples are given to illustrate the differences between programmed instruction and the more common transmission model of teaching. A final section provides suggestions on specific techniques of successive approximation.     

Contested terms and philosophical debates

There are two standard theoretical responses to putative errors in ordinary thinking about some given target property: eliminativism or revisionism. Roughly, eliminativism is the denial that the target property exists, and revisionism is the view that the property exists, but that people tend to have false beliefs about it. Recently, Shaun Nichols has proposed a third option: discretionism. Discretionism is the idea that some terms have multiple reference conventions, so that it may be true to say with eliminativists that the property does not exist, and true to say with revisionists (and others) that the property does exist. This article explores the viability of discretionism, and argues that it faces serious difficulties. Even if the difficulties faced by discretionism can be overcome, it is unclear that discretionism secures anything beyond what is already available to standard revisionist views. The article concludes with some reflections about Nichols’ account of the bare retributive norm.     

Stereotypic explanatory bias: Implicit stereotyping as a predictor of discrimination

Two experiments examined whether a measure of implicit stereotyping based on the tendency to explain Black stereotype-incongruent events more often than Black stereotype-congruent events (Stereotypic Explanatory Bias or SEB) is predictive of behavior toward a partner in an interracial interaction. In Experiment 1 SEB predicted White males’ choice to ask stereotypic questions of a Black female (but not a White male or White female) in an interview. In Experiment 2 the type of explanation (internal or external attribution) made for stereotype-inconsistency was examined. Results showed that White participants who made internal attributions for Black stereotype-incongruent behavior were rated more positively and those who made external attributions were rated more negatively by a Black male confederate. These results point to the potential of implicit stereotyping as an important predictor of behavior in an interracial interaction.     

Blocking incidental frustration during bargaining

The current study examined the effects of an intervention aimed at blocking the transfer of frustration from a previous experience (i.e. recall task) to a subsequent and unrelated task (i.e. ultimatum bargaining task). Participants who went through the intervention were more likely to accept unfair offers in the ultimatum bargaining task than those who did not go through the intervention. These results show that participants who were blocked from transferring their feelings of frustration from the recall task to the subsequent bargaining task (no-transfer condition) more likely accepted unfair offers than those who inadvertently transferred their feelings of frustration (transfer condition). The effect of conditions on accept-reject decisions in the ultimatum bargaining was mediated by reported feelings of frustration.     

Using and being used by categories. The case of negative evaluations and daily well-being

Three studies involving 257 undergraduates examined whether a simple choice reaction time task could predict daily experiences of affect. Individuals who were fast to make negative evaluations experienced more negative affect and more somatic symptoms and were less satisfied with their lives, compared with individuals who were slow to make negative evaluations. A fourth study, involving 89 undergraduates, indicated that performance on the task was relatively unaffected by transitory mood states. The results support the idea that categorization provides a useful perspective on personality functioning.     

A daughter's retrospective of B. F. Skinner

This paper describes characteristic behaviors of my father, B. F. Skinner, using family documents and my own recollections. Early contingencies in his upbringing strengthened his love of building things and his independence in discovering how the world works. Those skills, combined with a lack of supervision in graduate school, set the stage for his discovery of the operant. He did not stop with laboratory research. He extended his discovery of how consequences select behavior into education and the design of cultural practices. As well as solving society's problems, my father was always concerned with improving his own behavior. Some of the contingencies he set up to maximize his own productivity are described.     

Trait as default: extraversion, subjective well-being, and the distinction between neutral and positive events

On the basis of prior work suggesting that trait self-knowledge serves a "fill-in" function when event-specific information is missing (M.D. Robinson & G. L. Clore, 2002a), we sought to demonstrate that extraversion is a more reliable predictor of subjective well-being (SWB) judgments among certain individuals than among others. Four studies involving a total of 260 participants revealed that the extraversion-SWB relation was relatively weaker among those quick to appreciate the distinction between neutral and positive events in a choice reaction-time task; by contrast, it was stronger among those slow to recognize this distinction. The findings suggest that extraversion scales measure (among other things) beliefs about SWB that differentially contribute to judgments among those less capable of making evaluative distinctions at encoding.     

Development and validation of the Granada Burnout Questionnaire in Spanish police

The goal of the present study is to develop a questionnaire, with proper psychometric properties and current norms, to evaluate the burnout syndrome in Spain. The operative definition of burnout proposed by Maslach and Jackson is used to define three dimensions (Emotional exhaustion, Depersonalization and Personal accomplishment). A total of 2,403 national Spanish police participated. Evidence of construct validity was checked through cross validation (showing a good fit of the three factors model to the data). Using the MBI, NEO-FII and CECAD evidence of convergent validity and criteria validity were developed (showing that the relations are similar to the ones that appear in other research). The discrimination, mean, standard deviation, and typical error of the average of the items composing the various dimensions were analyzed. Both the Cronbach's alpha coefficient and the conditional standard error of measurement (CSEM) were calculated for each of the dimensions. The results showed good internal consistency (all α values > .85). Finally, the questionnaire was scaled using T scores. The psychometrical properties reported here support the use of this new questionnaire for the burnout evaluation in Spanish police.