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801.
Gap junctions are important to how the brain functions but are relatively under-investigated with respect to their contribution towards behaviour. In the present study a single trial discrimination avoidance task was used to investigate the effect of the gap junction inhibitor 18-α-glycyrrhetinic acid (αGA) on retention. Past studies within our research group have implied a potential role for gap junctions during the short-term memory (STM) stage which decays by 15 min post-training. A retention function study comparing 10 μM αGA and vehicle given immediately post-training demonstrated a significant main effect for drug with retention loss at all times of test (10–180 min post-training). Given that the most common gap junction in the brain is that forming the astrocytic network it is reasonable to conclude that αGA was acting upon these. To confirm this finding and interpretation two additional investigations were undertaken using endothelin-1 (ET-1) and ET-1 + tolbutamide. Importantly, a retention function study using 10 nM ET-1 replicated the retention loss observed for αGA. In order to confirm that ET-1 was acting on astrocytic gap junctions the amnestic action of ET-1 was effectively challenged with increasing concentrations of tolbutamide. The present findings suggest that astrocytic gap junctions are important for memory processing. 相似文献
802.
Vanessa LoBue 《Journal of experimental child psychology》2010,107(1):59-66
Spiders are among the most common targets of fears and phobias in the world. In visual search tasks, adults detect their presence more rapidly than other kinds of stimuli. Reported here is an investigation of whether young children share this attentional bias for the detection of spiders. In a series of experiments, preschoolers and adults were asked to find the single spider picture among an array of eight mushrooms or cockroaches or the reverse. Both children and adults detected the presence of spiders more rapidly than both categories of distracter stimuli. Furthermore, there was no difference between the detection of two neutral stimuli (cockroaches vs. mushrooms). These results provide the first evidence of enhanced visual detection of spiders in young children. 相似文献
803.
Pedro Pechorro Vanessa Caramelo João Pedro Oliveira Cristina Nunes Shelby R. Curtis Daniel N. Jones 《Deviant behavior》2019,40(3):273-286
The dark triad is a term used to describe a constellation of three socially harmful personality traits: Machiavellianism, psychopathy, and narcissism. The main aim of the present study was to examine the psychometric properties of the Short Dark Triad (SD3) scale, a brief measure of the dark triad, among a sample (N = 412) of male (n = 200) and female (n = 212) at-risk Portuguese youths. Confirmatory factor analysis revealed the three-factor structure of the SD3 obtained an adequate fit, and measurement invariance across gender was demonstrated, although two items per dimension had to be removed. The Portuguese version of the SD3 scale demonstrated satisfactory psychometric properties, specifically the properties of internal consistency, convergent validity, discriminant validity, and known-groups validity, which overall justifies its use among this population. Findings are discussed in terms of the use of the SD3 scale with male and female at-risk youths. 相似文献
804.
Jason Brown Samantha Wiendels Vanessa Eyre 《Counselling and Psychotherapy Research》2019,19(4):533-543
The purpose of the present study was to identify social justice competencies from the perspective of psychotherapists engaged in therapeutic practice. Twenty‐five therapists were asked, “What social justice competencies do psychotherapists need?” Responses were analysed using the concept mapping method. Nine participants grouped all unique interview responses into groups. Multidimensional scaling and cluster analysis were applied. The six competency areas identified included community activism, political influence on clinical work, critical consciousness, social responsibility, self‐awareness and personal style. The results were compared and contrasted with the literature. Considerable overlap was noted. The main differences concerned the need for collaboration as an advocacy tactic, as well as local knowledge about the pressing social issues affecting members of the community within which one practices. 相似文献
805.
806.
We investigated how people design interventions to affect the outcomes of causal systems. We propose that the abstract structural properties of a causal system, in addition to people's content and mechanism knowledge, influence decisions about how to intervene. In Experiment 1, participants preferred to intervene at specific locations (immediate causes, root causes) in a causal chain regardless of which content variables occupied those positions. In Experiment 2, participants were more likely to intervene on root causes versus immediate causes when they were presented with a long‐term goal versus a short‐term goal. These results show that the structural properties of a causal system can guide the design of interventions. 相似文献
807.
Jodi M. Gilman Randi M. Schuster Max T. Curran Vanessa Calderon Andre van der Kouwe A. Eden Evins 《Cognitive, affective & behavioral neuroscience》2016,16(4):646-661
Though social influence is a critical factor in the initiation and maintenance of marijuana use, the neural correlates of influence in those who use marijuana are unknown. In this study, marijuana-using young adults (MJ; n = 20) and controls (CON; n = 23) performed a decision-making task in which they made a perceptual choice after viewing the choices of unknown peers via photographs, while they underwent functional magnetic resonance imaging scans. The MJ and CON groups did not show differences in the overall number of choices that agreed with versus opposed group influence, but only the MJ group showed reaction time slowing when deciding against group choices. Longer reaction times were associated with greater activation of frontal regions. The MJ goup, compared to CON, showed significantly greater activation in the caudate when presented with peer information. Across groups, caudate activation was associated with self-reported susceptibility to influence. These findings indicate that young adults who use MJ may exhibit increased effort when confronted with opposing peer influence, as well as exhibit greater responsivity of the caudate to social information. These results not only better define the neural basis of social decisions, but also suggest that marijuana use is associated with exaggerated neural activity during decision making that involves social information. 相似文献
808.
Louis Renoult Leia Kopp Patrick S. R. Davidson Vanessa Taler Cristina M. Atance 《Quarterly journal of experimental psychology (2006)》2016,69(2):299-309
It has been argued that adults underestimate the extent to which their preferences will change over time. We sought to determine whether such mispredictions are the result of a difficulty imagining that one's own current and future preferences may differ or whether it also characterizes our predictions about the future preferences of others. We used a perspective-taking task in which we asked young people how much they liked stereotypically young-person items (e.g., Top 40 music, adventure vacations) and stereotypically old-person items (e.g., jazz, playing bridge) now, and how much they would like them in the distant future (i.e., when they are 70 years old). Participants also made these same predictions for a generic same-age, same-sex peer. In a third condition, participants predicted how much a generic older (i.e., age 70) same-sex adult would like items from both categories today. Participants predicted less change between their own current and future preferences than between the current and future preferences of a peer. However, participants estimated that, compared to a current older adult today, their peer would like stereotypically young items more in the future and stereotypically old items less. The fact that peers’ distant-future estimated preferences were different from the ones they made for “current” older adults suggests that even though underestimation of change of preferences over time is attenuated when thinking about others, a bias still exists. 相似文献
809.
810.
According to attentional control theory (ACT; Eysenck et al. in Emotion 7(2):336–353, 2007) anxious individuals recruit motivation on demanding tasks, which helps prevent performance shortfalls. We used a quasi-experimental design to examine the relationship between trait anxiety (operationalised using questionnaire scores), situational stress (manipulated using ego threat instructions) and motivation (indexed using a self-report goal-commitment scale) in predicting effectiveness (accuracy) and efficiency (accuracy divided by RT) on the reading span task. After controlling for depression, the variables were not related to effectiveness; however there was a significant trait anxiety × goal-commitment interaction on reading span efficiency. Higher trait anxiety predicted better efficiency at higher goal-commitment, and poorer efficiency at lower goal-commitment, and these relationships were independent of situational stress. Results are interpreted in terms of ACT. 相似文献