Building Capacity of State Adolescent Pregnancy Prevention Coalitions to Implement Science-Based Approaches

A central question in adolescent reproductive health circles is how to effectively disseminate research to practitioners in a way that supports them in using the most scientifically sound and effective programming. In 2002, the Division of Reproductive Health at the Centers for Disease Control and Prevention (CDC) tackled this question by funding three national-level and five state-level organizations focused on adolescent pregnancy prevention to promote the use of science-based programs and approaches. Healthy Teen Network (HTN) and Education, Training and Research Associates (ETR), two national organizations, have partnered under this CDC funding to implement an effective model for capacity building. This paper provides an overview of the approaches used by HTN and ETR in capacity building using a seven-step process. We describe how we modified the Interactive Systems Framework for Dissemination and Implementation (ISF) for science-based innovations to apply to capacity-building for adolescent reproductive health (ARH) programs, and how we developed relevant, sustainable training and technical support. We conclude by reviewing some of the results of this training, and discuss the future work that will likely continue to advance the science behind effective dissemination of ARH research to practice.     

Air pollution, cognitive deficits and brain abnormalities: a pilot study with children and dogs

Exposure to air pollution is associated with neuroinflammation in healthy children and dogs in Mexico City. Comparative studies were carried out in healthy children and young dogs similarly exposed to ambient pollution in Mexico City. Children from Mexico City (n: 55) and a low polluted city (n:18) underwent psychometric testing and brain magnetic resonance imaging MRI. Seven healthy young dogs with similar exposure to Mexico City air pollution had brain MRI, measurement of mRNA abundance of two inflammatory genes cyclooxygenase-2, and interleukin 1 beta in target brain areas, and histopathological evaluation of brain tissue. Children with no known risk factors for neurological or cognitive disorders residing in a polluted urban environment exhibited significant deficits in a combination of fluid and crystallized cognition tasks. Fifty-six percent of Mexico City children tested showed prefrontal white matter hyperintense lesions and similar lesions were observed in dogs (57%). Exposed dogs had frontal lesions with vascular subcortical pathology associated with neuroinflammation, enlarged Virchow-Robin spaces, gliosis, and ultrafine particulate matter deposition. Based on the MRI findings, the prefrontal cortex was a target anatomical region in Mexico City children and its damage could have contributed to their cognitive dysfunction. The present work presents a groundbreaking, interdisciplinary methodology for addressing relationships between environmental pollution, structural brain alterations by MRI, and cognitive deficits/delays in healthy children.     

Training and Mentoring of Chemists: A Study of Gender Disparity

This study was conducted to compare women’s and men’s retrospective perceptions of the mentoring they received during their training and career development in chemistry. Participants were 455 graduates (135 women) who received doctoral degrees from 11 top US chemistry programs over a 5-year period (1988–1992). In 2003, graduates completed surveys of undergraduate, graduate, post-doctoral, and initial employment experiences. In line with Social Cognitive Career Theory (Lent et al., Journal of Vocational Behavior 45:79–122, 1994), which posits that perceptions of barriers can affect career decisions, results suggest that women perceived that they received less mentoring than men at the undergraduate, graduate, and post-doctoral levels of training, likely related to gender differences in eventual career success. Possible interventions at the individual and institutional levels are discussed.     

Explaining contradictory relations between risk perception and risk taking

Different studies have documented opposite relations between perceived risk and behavior. The present study tested a theoretical explanation that reconciles these conflicting results. Adolescents (N= 596) completed alternative measures of risk perception that differed in cue specificity and response format. As predicted by fuzzy-trace theory, measures that emphasized verbatim retrieval and quantitative processing produced positive correlations between perceived risk and risky behavior; risk perceptions reflected the extent to which adolescents engaged in risky behavior. In contrast, measures that assessed global, gist-based judgments of risk produced negative correlations; higher risk perceptions were associated with less risk taking, a protective rather than reflective relation. Endorsement of simple values and principles provided the greatest protection against risk taking. Results support a dual-processes interpretation of the relation between risk perception and risk taking according to which observed relations depend on whether the cues in questions trigger verbatim or gist processing.     

Practical Reason and the Stability Standard

Practical reasoning, reasoning about what to do, is a very familiar activity. When we think about whether to cook or to go out for dinner, to buy a house or rent, or to study law or business, we are engaged in practical reasoning. If the kind of reasoning we engage in is truly a rational process, there must be some norms or standards that govern it; the process cannot be arbitrary or random. In this paper I argue that one of the standards that governs practical reasoning is the stability standard. The stability standard, I argue, is a norm that is constitutive of practical reasoning: insofar as we do not take violations of this norm to be relevant considerations, we do not count as engaged in reasoning at all. Furthermore, I argue that it is a standard we can explicitly employ in order to deliberate about our ends or desires themselves. Importantly, this standard will not require that some ends are prescribed or determined by reason alone. The stability standard, therefore, allows us to retain some of the attractive features of instrumentalism without accepting the implication that there is no rational way to evaluate ends.     

Self-Injurious Thoughts and Behaviors Interview: development, reliability, and validity in an adolescent sample

The authors developed the Self-Injurious Thoughts and Behaviors Interview (SITBI) and evaluated its psychometric properties. The SITBI is a structured interview that assesses the presence, frequency, and characteristics of a wide range of self-injurious thoughts and behaviors, including suicidal ideation, suicide plans, suicide gestures, suicide attempts, and nonsuicidal self-injury (NSSI). This initial study, based on the administration of the SITBI to 94 adolescents and young adults, suggested that the SITBI has strong interrater reliability (average kappa = .99, r = 1.0) and test-retest reliability (average kappa = .70, intraclass correlation coefficient = .44) over a 6-month period. Moreover, concurrent validity was demonstrated via strong correspondence between the SITBI and other measures of suicidal ideation (average kappa = .54), suicide attempt (kappa = .65), and NSSI (average kappa = .87). The authors concluded that the SITBI uniformly and comprehensively assesses a wide range of self-injury-related constructs and provides a new instrument that can be administered with relative ease in both research and clinical settings.     

The influence of eye-gaze and arrow pointing distractor cues on voluntary eye movements

We investigated Ricciardelli et al.'s (2002) claim, that the tendency for gaze direction to elicit automatic attentional following is unique to biologically significant information. Participants made voluntary saccades to targets on the left or the right of a display, which were either congruent or incongruent with a centrally presented distractor (eye-gaze or arrow). Contrary to Ricciardelli et al., for both distractor types, saccade latencies were slower, and participants made more directional errors, on incongruent than on congruent trials. Moreover, a cost-benefit analysis showed no difference between the two distractor types. However, latencies for erroneous saccades were faster than correctly directed saccades for the eye-gaze distractors, but not for the arrow distractors.     

Creativity, unique designs, and schizotypy in a nonclinical sample

The present study examined whether creativity and novel design construction differ in 60 individuals who scored low and high (based on a median split) on a measure of schizotypy. Groups differed on one measure, total designs made, but not on creativity.