Experts in science: a view from the trenches

In this paper I analyze four so-called “principles of expertise”; that is, good epistemic practices that are normatively motivated by the epistemological literature on expert judgment. I highlight some of the problems that the four principles of expertise run into, when we try to implement them in concrete contexts of application (e.g. in science committees). I suggest some possible alternatives and adjustments to the principles, arguing in general that the epistemology of expertise should be informed both by case studies and by the literature on the use of experts in science practice.     

BDNF serum levels in subjects developing or not post-traumatic stress disorder after trauma exposure

Post-traumatic stress disorder (PTSD) is a syndrome resulting from exposure to a severe traumatic event that poses threatened death or injury and produces intense fear and helplessness. The neural structures implicated in PTSD development belong to the limbic system, an important region for emotional processing. Brain-derived neurotrophic factor (BDNF) is a neurotrophin that serves as survival factor for selected populations of central nervous system (CNS) neurons and plays a role in the limbic system by regulating synaptic plasticity, memory processes and behavior. Impaired BDNF production in the brain can lead to a variety of CNS dysfunctions including symptoms associated with PTSD. However, so far fewer studies have investigated this neurotrophin in patients with PTSD. Furthermore, given the multiple role of BDNF in various CNS disorders, it cannot be excluded that traumatic events per se may influence neurotrophin levels, without a direct association to the PTSD syndrome.     

Validation and Standardization of the Dutch Trauma Symptom Checklist for Young Children in a Normative and Clinical Sample

The study aimed to describe the psychometric properties of the Dutch version of the Trauma Symptom Checklist for Young Children (TSCYC) in normative and clinical populations in the Netherlands. Caregivers’ ratings on the TSCYC were obtained for 1,802 children from the normal population, and for 515 children from a clinical population of traumatized children. In the clinical sample, additional measures were taken. The internal consistency and test-retest reliability of TSCYC scales were adequate. Confirmatory factor analysis showed acceptable fit on the putative scale structure. Regarding criterion validity, the clinical sample scored significantly higher on all clinical scales when compared to the normal population sample. Within the clinical sample, significant associations were found between TSCYC scales and convergent scales of other instruments. The Posttraumatic Stress-Total subscale demonstrated excellent discriminative ability between traumatized children and children from the normal population. The Dutch version of the TSCYC proved a valid and reliable instrument to measure trauma symptoms in young children through caregiver report, similar to the original American version. Further comparisons with diagnostic interviews are warranted.     

Principles for Object-Linguistic Consequence: from Logical to Irreflexive

We discuss the principles for a primitive, object-linguistic notion of consequence proposed by (Beall and Murzi, Journal of Philosophy, 3 pp. 143–65 (2013)) that yield a version of Curry’s paradox. We propose and study several strategies to weaken these principles and overcome paradox: all these strategies are based on the intuition that the object-linguistic consequence predicate internalizes whichever meta-linguistic notion of consequence we accept in the first place. To these solutions will correspond different conceptions of consequence. In one possible reading of these principles, they give rise to a notion of logical consequence: we study the corresponding theory of validity (and some of its variants) by showing that it is conservative over a wide range of base theories: this result is achieved via a well-behaved form of local reduction. The theory of logical consequence is based on a restriction of the introduction rule for the consequence predicate. To unrestrictedly maintain this principle, we develop a conception of object-linguistic consequence, which we call grounded consequence, that displays a restriction of the structural rule of reflexivity. This construction is obtained by generalizing Saul Kripke’s inductive theory of truth (strong Kleene version). Grounded validity will be shown to satisfy several desirable principles for a naïve, self-applicable notion of consequence.     

In search of shared and nonshared environmental factors in security of attachment: a behavior-genetic study of the association between sensitivity and attachment security

The current article presents results from a twin study of genetic and environmental components of maternal sensitivity and infant attachment and their association. The sample consisted of 136 twin pairs from 2 sites: Leiden, the Netherlands, and London, UK. Maternal sensitivity was assessed in the home at 9-10 months, and infant attachment security was observed in the laboratory at 12 months. The study yielded little evidence that genetic factors are involved in variations between twins in maternal sensitivity ratings but did find that shared variance in maternal sensitivity was able to account for some of the similarity between twins in attachment security. Weak nonshared associations between sensitivity and attachment appeared to suppress the magnitude of the correlation between attachment and sensitivity in twin children. The results could indicate that the attachment security of one twin may depend on the relationship the parent has with the other twin. The results are brought to bear on the validity of attachment theory as a theory of primarily shared environmental effects in children's development and the continuing challenge posed to attachment theory by within-family differences in socioemotional processes.     

The validity of the hospital anxiety and depression scale and the geriatric depression scale in Parkinson's disease

We assessed the concurrent validity of the Hospital Anxiety and Depression Scale (HADS) and the Geriatric Depression Scale (GDS) against the Hamilton Rating Scale for Depression (Ham-D) in patients with Parkinson's disease (PD). Forty-six non-demented PD patients were assessed by a neurologist on the Ham-D. Patients also completed four mood rating scales: the HADS, the GDS, the VAS and the Face Scale. For the HADS and the GDS, Receiver Operating Characteristics (ROC) curves were obtained and the positive and negative predictive values (PPV, NPV) were calculated for different cut-off scores. Maximum discrimination between depressed and non-depressed PD patients was reached at a cut-off score of 10/11 for both the HADS and the GDS. At the same cut-off score of 10/11 for both the HADS and the GDS, the high sensitivity and NPV make these scales appropriate screening instruments for depression in PD. A high specificity and PPV, which is necessary for a diagnostic test, was reached at a cut-off score of 12/13 for the GDS and at a cut-off score of 11/12 for the HADS. The results indicate the validity of using the HADS and the GDS to screen for depressive symptoms and to diagnose depressive illness in PD.     

Fitch’s paradox and <Emphasis Type="Italic">ceteris paribus</Emphasis> modalities

The paper attempts to give a solution to the Fitch’s paradox though the strategy of the reformulation of the paradox in temporal logic, and a notion of knowledge which is a kind of ceteris paribus modality. An analogous solution has been offered in a different context to solve the problem of metaphysical determinism.     

The limits of definition: Gadamer’s critique of Aristotle’s ethics

ABSTRACT

There is a recent scholarly trend drawing similarities between Aristotle’s conceptions of ethics and demonstrative science. One such similarity has become widely and rightly recognized: for Aristotle both ethics and demonstrative science seek essential definitions of phenomena. The task of the paper is to show that German philosopher and classicist Hans-Georg Gadamer not only prefigured this interpretative trend, he also identified a problematic feature of Aristotle’s method so construed. The problematic feature is semantic. For Aristotle essential definitions must consist of univocal terms, but such univocity cannot be maintained if the definienda and definientes are concepts to be usefully employed in everyday ethical judgements. Gadamer therefore points out a problematic tension in Aristotle’s ethics. On the one hand, ethical inquiry should have practical application, but, on the other hand, the semantic assumptions underlying inquiry imply that it cannot.     

Frege: two theses,two senses

One particular topic in the literature on Frege's conception of sense relates to two apparently contradictory theses held by Frege: the isomorphism of thought and language on one hand and the expressibility of a thought by different sentences on the other. I will divide the paper into five sections. In (1) I introduce the problem of the tension in Frege's thought. In (2) I discuss the main attempts to resolve the conflict between Frege's two contradictory claims, showing what is wrong with some of them. In (3), I analyse where, in Frege'ps writings and discussions on sense identity, one can find grounds for two different conceptions of sense. In (4) I show how the two contradictory theses held by Frege are connected with different concerns, compelling Frege to a constant oscillation in terminology. In (5) I summarize two further reasons that prevented Frege from making the distinction between two conceptions of sense clear: (i) the antipsychologism problem and (ii) the overlap of traditions in German literature contemporary to Frege about the concept of value. I conclude with a hint for a reconstruction of the Fregean notion of ‘thought’ which resolves the contradiction between his two theses.