Reduced spiking in entorhinal cortex during the delay period of a cued spatial response task

Intrinsic persistent spiking mechanisms in medial entorhinal cortex (mEC) neurons may play a role in active maintenance of working memory. However, electrophysiological studies of rat mEC units have primarily focused on spatial modulation. We sought evidence of differential spike rates in the mEC in rats trained on a T-maze, cued spatial delayed response task. Animals begin at the base of the T-maze where a 1-sec white noise and visual light cue are presented on the left or right side of the maze. Rats are rewarded for responding toward the cued direction. In correct trials, we observed decreased spike rates during the delay period, the time interval between cue presentation and reward delivery. Firing-rate histograms show significant decreases during the delay period compared to 5-sec windows from both pre-cue and post-reward periods. We analyzed how running speed and trajectory specificity correlated to spike rate. Twice as many cells were responsive to cue alone compared to running speed. Trajectory specificity did not relate significantly to firing rate. Decreased spike rate may reflect active maintenance in other structures inhibiting mEC. Alternately, the reduction may reflect decreases in background activity during enhanced attention and cholinergic modulation. Lastly, animals often ran through the T-maze choice-point with varying speed. We calculated the spatial posterior probability density from spike rates during these choice-point passes. Slow passes through the choice point were characterized by greater probability of decoding to the reward locations on correct trials compared to quick passes on the maze consistent with similar "look-ahead" properties previously reported in the hippocampus and ventral striatum.     

Comparability of Self‐Reported Conscientiousness Across 21 Countries

In cross‐national studies, mean levels of self‐reported phenomena are often not congruent with more objective criteria. One prominent explanation for such findings is that people make self‐report judgements in relation to culture‐specific standards (often called the reference group effect), thereby undermining the cross‐cultural comparability of the judgements. We employed a simple method called anchoring vignettes in order to test whether people from 21 different countries have varying standards for Conscientiousness, a Big Five personality trait that has repeatedly shown unexpected nation‐level relationships with external criteria. Participants rated their own Conscientiousness and that of 30 hypothetical persons portrayed in short vignettes. The latter type of ratings was expected to reveal individual differences in standards of Conscientiousness. The vignettes were rated relatively similarly in all countries, suggesting no substantial culture‐related differences in standards for Conscientiousness. Controlling for the small differences in standards did not substantially change the rankings of countries on mean self‐ratings or the predictive validities of these rankings for objective criteria. These findings are not consistent with mean self‐rated Conscientiousness scores being influenced by culture‐specific standards. The technique of anchoring vignettes can be used in various types of studies to assess the potentially confounding effects of reference levels. Copyright © 2011 John Wiley & Sons, Ltd.     

Converting virtual community members into online buyers

Although many online vendors have sponsored virtual communities (VCs) in the hope of reaping commercial benefits from it, not many have been successful in reaping commercial benefits from their VC. Online vendors can benefit greatly from having a VC, if the VC members can be converted into online buyers. This study examines the conversion of a VC member into an online buyer. Using a classical-conditioning approach, this study finds that members' committed participation in the VC is the springboard for online vendors to convert VC members into online buyers.     

A new high-pressure phase transition in a zirconium-niobium alloy

It is reported for the first time that a g M y transformation can be induced in a g -stabilized zirconium alloy subjected to shock pressure. The y phase formed in the g matrix has been found to have a plate shape akin to martensitic plates. The lattice correspondence between the g and y structures has been found to be the same as that produced by thermal treatment. The formation of the plate-shaped y phase is explained in terms of a mechanism involving shear on <112> planes of the bcc lattice and the mechanical instability of the g phase.     

Primacy and recency in nonword repetition

An increasing body of evidence suggests that nonword repetition is related to immediate serial memory (e.g., ; ). One possible account of this relationship is that a nonword is processed like a list when it is first encountered. If this is the case, it should be possible to detect serial position effects in repetition of single nonwords. Three experiments tested this prediction. Experiment 1 examined whether there would be syllable serial position primacy and recency effects in repetition of polysyllabic nonwords, and obtained both primacy and recency effects. Experiments 2 and 3 showed that these effects were not due to the controlled duration of the nonwords or the requirements of concurrent articulation or the procedure by which nonwords were created.     

Notes on Kant's derivation of the various formulae of the categorical imperative

Abstract

This article is concerned with examining Kant's derivation of the various formulae of his Categorical Imperative. It is in agreement with Paton in maintaining that Kant actually mentions five formulae. But it is not in agreement with him, and some others, in maintaining that they are ultimately reducible to three. Nor is it in agreement with those who maintain that they are ultimately reducible to just one. According to the present article, they are ultimately reducible to two: that about a moral law being a universal law; and that about a moral law involving treating human beings as ends in themselves.     

Specific Cognitive Deficits in ADHD: A Diagnostic Concern in Differential Diagnosis

We present a critical account of existing tools used to diagnose children with Attention Deficit Hyperactivity Disorder and to make a case for the assessment of cognitive impairments as a part of diagnostic system. Surveys have shown that clinicians rely almost entirely upon subjective reports or their own clinical judgment when arriving at diagnostic decisions relating to this prevalent disorder. While information from parents and teachers should always be carefully considered, they are often influenced by a host of emotional and perceptual factors. It increases the possibility for misdiagnosis of a condition like ADHD. Recent experimental literature on ADHD has identified unique underlying cognitive dysfunction, specific to ADHD. Therefore, we propose that there is a need to incorporate information on cognitive mechanisms underlying ADHD and inculcate such information in the diagnostic system, which will provide a more sensitive as well as specific tool in differential diagnosis of ADHD.     

Communalism, familism, and filial piety: are they birds of a collectivist feather?

The present studies examined the extent to which (a) communalism, familism, and filial piety would pattern onto a single family/relationship primacy construct; (b) this construct would be closely related to indices of collectivism; and (c) this construct would be related to positive psychosocial functioning and psychological distress. In Study 1, 1,773 students from nine colleges and universities around the United States completed measures of communalism, familism, and filial piety, as well as of individualistic and collectivistic values. Results indicated that communalism, familism, and filial piety clustered onto a single factor. This factor, to which we refer as family/relationship primacy, was closely and positively related to collectivism but only weakly and positively related to individualism and independence. In Study 2, 10,491 students from 30 colleges and universities in 20 U.S. states completed measures of communalism, familism, and filial piety, as well as of positive psychosocial functioning and psychological distress. The family/relationship primacy factor again emerged and was positively associated with both positive psychosocial functioning and psychological distress. Clinical implications and future directions for the study of cultural values are discussed.     

BHAGAVAD GĪTĀ AS DUTY AND VIRTUE ETHICS

The paper examines the ethical conception of the most well‐known and much discussed Hindu text, the Bhagavad Gītā, in the context of the Western distinction between duty ethics and virtue ethics. Most of the materials published on the Gītā make much of its conception of duty; however, there is no systematic investigation of the notion of virtue in the Gītā. The paper begins with a discussion of the fundamental characteristics of virtue ethics, before undertaking a discussion of the conceptions of duty and virtue in the Gītā. The paper clearly demonstrates that (1) both duty and virtue coexist in the Gītā, and (2) the Gītā accords virtue an important place.