Dealing with labyrinths. General practice and research in psychoanalysis--an evaluation

If psychotherapy research is to yield results relevant for therapeutic practice, it must broaden its receptiveness for the peculiarities of this field and for the methods employed by therapists. The therapist works on-line, while the researcher enjoys the advantage of working off-line. Research in psychotherapy has addressed the world of images and affects, the interactive process, the dependence on models, and the specific manner of information processing characteristic of therapy. The author compares the different ways in which the therapeutic and the empirical settings handle suspicion and error.     

Simultaneous effects and aftereffects of the intensity and success aspect in coping with stresses

Intensity and success of coping processes in achievement-related situations are very often tightly connected. Therefore, the specific empirical status of each of the two aspects is unclear. In the current study a technique is introduced which allows orthogonal variation of both components. 64 subjects were confronted with a simple perceptual-speed task in which objective success rate was held constant by a computer-based adaptive process. Graphic feedback was provided about the objective success rate in relation to one of two different success criteria. For half of the subjects the criterion was above (failure condition) and for the other half it was below (success condition) the adaptively controlled success rate. Intensity, the second between-subjects factor, was manipulated by presenting either a high or a low number of items per time unit. As an additional quasi-experimental factor, the degree of action- vs. state-orientation (Kuhl, 1983) was included. The results showed highly specific effects for both the intensity and the failure/success dimension: High intensity resulted in an increase of electrodermal activity which could be observed throughout a one hour post-stressor phase. The failure/success variation had effects mainly on subjective variables representing appraisal of controllability and produced no after-effects. Especially strong effects on subjective variables could be observed when state-oriented subjects were confronted with both failure and high intensity.     

Hippocampal deafferentation: transplantderived reinnervation and functional recovery

A brief review is provided of the capacity of neural tissue transplants to reinnervate the deafferented hippocampus and repair functional deficits induced by the lesion. The techniques for transplantation of solid pieces of embryonic septum, locus coeruleus or raphe nuclei, or tissue suspensions of embryonic septum, to the adult rat hippocampus are described. Such grafts manifest good long-term survival, provide a good reinnervation of the hippocampus that is histochemically and biochemically appropriate and specific, can establish ultrastructural synaptic contacts with the host, and are electrophysiologically active. Rats with septal grafts manifest recovery of the capacity to learn certain aspects of radial 8-arm maze, T-maze alternation and Morris water-maze tasks. Rats with locus coeruleus grafts manifest an amelioration of lesion-induced hyperactivity. It is concluded that neural tissue transplantation provides a powerful new tool in the study of the functional organization of the hippocampus and its various neurotransmitter-specific afferent systems.     

Functional recovery following brain damage: conceptual frameworks and biological mechanisms

Mammals are well known to manifest recovery over time of many functional impairments induced by brain lesions. A brief reveiw is provided of the different conceptual frameworks within which functional recovery has been examined in the literature, and of different neurobiological mechanisms that have been proposed to account for the phenomenon. We observe that these two levels of analysis have frequently been only loosely related. Finally, a newly identified biological mechanism—compensatory collateral sprouting—is described which appears to be closely related to functional recovery in animals with hippocampal lesions, and this is proposed as a powerful new model within which to investigate further the relationship between the phenomenon of functional recovery and its underlying mechanisms.     

Assessing social competencies in lower income preschool children

This study examined social competencies in 4-year-old, lower income, nonwhite preschool children in a replication of work by Shure, Spivack, and Jaeger. Age differential interpersonal cognitive problem-solving skills were investigated, i.e., ability to generate alternative solutions to interpersonal problems, consequential thinking, and school achievement as they relate to behavioral adjustment ratings by teachers and independent observers. A teacher's rating of a child as aberrant or adjusted predicted an independent observer's rating of that child in a naturalistic setting. Children who were rated as adjusted by their teachers had significantly higher scores on an achievement inventory than those children who were rated aberrant, but the study did not find the predicted relationship between problem-solving thinking and adjustment. A version of this paper was presented at the annual meeting of the American Psychological Association, New York, September 1979. The study was supported by grants from the McGregor Fund, the Eloise and Richard Webber Foundation, the David M. Whitney Fund and by the Detroit Public Schools Region 7, for which the authors express grateful appreciation. The authors also wish to thank Myrna B. Shure for her help in carrying out this replication.     

Some problems of Wilson's disease

The Leipzig Center for Wilson's Disease in the GDR is charged with the registration and diagnosis of all homozygous Wilson gene carriers, the clarification of all suspected cases, including the heterozygote test, and the co-ordination of long-term treatment. At present, there are 78 recorded Wilson gene carriers living. On the basis of our own comprehensive observations and investigations over prolonged periods of time, questions concerning pathogenesis, genetics, diagnosis and therapeutic measures, including their side-effects, are dealt with.     

Experimentally induced phonological paraphasias.

A motor aphasic patient had to repeat word lists that contained, among other things, words with the sequences r - r - l and l - l - r. These sequences were often repeated as l - r - l (anticipatory distant assimilation) and r - l - r (same type, but less frequently), respectively. These assimilations violate the cross-over constraint (or relevancy condition or adjacency principle) and thus represent another instance of a flagrant contradiction between pathological and normal (natural) phonological processes.     

Aortic isthmus stenosis from a neurological viewpoint

The etiology, pathogenesis, and clinical treatment of stenoses of the isthmus aortae are outlined. Following this, the particular case of a 41-year-old patient with typical stenosis of the isthmus of the aorta is reported. The course of disease required the need for a surgical operation, which had not initially been taken into consideration, to be reexamined. The patient, after performance on him of vascular restoration, is now on a part-time job. Using age as the sole circumstance indicating the inadvisability of performing a surgical operation in the case of stenosis of the isthmus aortae cannot any longer be considered justifiable.