The neural circuitry supporting goal maintenance during cognitive control: a comparison of expectancy AX-CPT and dot probe expectancy paradigms

Goal maintenance is an aspect of cognitive control that has been identified as critical for understanding psychopathology according to criteria of the NIMH-sponsored CNTRICS (Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia) and Research Domain Criteria (RDoC) initiatives. CNTRICS proposed the expectancy AX-CPT, and its visual-spatial parallel the dot probe expectancy (DPX), as valid measures of the cognitive and neural processes thought to be relevant for goal maintenance. The goal of this study was to specifically examine the functional neural correlates and connectivity patterns of both goal maintenance tasks in the same subset of subjects to further validate their neural construct validity and clarify our understanding of the nature and function of the neural circuitry engaged by the tasks. Twenty-six healthy control subjects performed both the letter (AX) and dot pattern (DPX) variants of the CPT during fMRI. Behavioral performance was similar between tasks. The 2 tasks engaged the same brain networks including dorsolateral prefrontal cortex (DLPFC) and dorsal parietal regions, supporting their validity as complementary measures of the goal maintenance construct. Interestingly there was greater engagement of the frontal opercular insula region during the expectancy AX-CPT (letter) and greater functional connectivity between the PFC and medial temporal lobe in the DPX (dot pattern). These differences are consistent with differential recruitment of phonological and visual-spatial processes by the two tasks and suggest that additional long-term memory systems may be engaged by the dot probe version.     

Guilty or Innocent? Women's Reliance on Inadmissible Evidence in a Simulated Rape Case

This study investigated the extent to which women disregard inadmissible evidence in a simulated rape case as a function of when they receive a judge's global legal instructions concerning presumption of innocence, burden of proof, reasonable doubt, and inadmissible evidence. We hypothesized that participants would be more likely to disregard incriminating inadmissible evidence when the instructions were given before rather than after the trial. Participants listened to audiotaped excerpts from a rape trial. They were given pretrial, predeliberation, or both sets of instructions; and received admissible or inadmissible avidence or no prior rape testimony, after which they made judgments. The results supported hypothesis that pretrial instructions are more effective than predeliberation instructions in allowing participants to disregard inadmissible evidence.
One cannot unring a bell; after the thrust of a saber, it is difficult to say forget the wound; and finally, if you throw a skunk into the jury box, you can't instruct the jury not to smell it ( Dunn v. United States , 1962 , p. 886).     

A Qualitative Exploration of Religion,Gender Norms,and Sexual Decision-Making within African American Faith-Based Communities

Human immunodeficiency virus (HIV) continues to be a prominent health and social justice issue, especially for African American communities in the Southern United States. Gender role norms, specifically within faith-based communities in the South, pose challenges to empowering women to make safer sexual health decisions. To explore perceptions of gender norms and sexual health, 42 qualitative interviews were gathered from female members of 16 predominantly African American churches in Atlanta, GA. Constructs from the theory of gender and power and the social ecological model were used to guide coding and analysis. Participants discussed their experiences with gender norms and gender-based power differentials at the institutional (i.e., church), familial, and interpersonal (i.e., intimate relationship) levels. Because of the attitudes and beliefs held by their religious communities and families, many participants recalled struggling to assert themselves in sexual relationships and recalled engaging in risky and unwanted sexual behavior, especially during their young adult years. However, as the participants matured, they worked to overturn traditional gender norms, empowering both their children and women in their religious communities to make healthy, autonomous sexual decisions. Moving forward, participants want their churches and members of their faith communities to play an active role in the empowerment of African American women and provide them with the confidence and education necessary to negotiate sexual decisions with their partners.

     

What we talk about when we talk about pediatric suffering

Theoretical Medicine and Bioethics - In this paper I aim to show why pediatric suffering must be understood as a judgment or evaluation, rather than a mental state. To accomplish this task, first I...     

Social Justice: Outcome and Procedure

A review of recent research demonstrates that people are more willing to accept decisions when they feel that those decisions are made through decision‐making procedures they view as fair. Studies of procedural justice judgements further suggest that people evaluate fairness primarily through criteria that can be provided to all the parties to a conflict: whether there are opportunities to participate; whether the authorities are neutral; the degree to which people trust the motives of the authorities; and whether people are treated with dignity and respect during the process. These findings are optimistic and suggest that authorities have considerable ability to bridge differences and interests and values through the use of fair decision‐making procedures. The limits to the effectiveness of such procedural approaches are also outlined.