干细胞移植治疗冠心病的现状与未来

冠心病仍然是全球的主要死亡原因.其所造成的心肌梗死及慢性心力衰竭对生活质量的影响和由此造成的高额医疗费用促使我们不断寻求新的医疗措施.近几年有关干细胞用于心肌梗死后心肌再生、心肌内新生血管形成,可能还会改善梗死后的心功能的研究成为心脏病学研究的最热门领域.尽管干细胞治疗有可能使心力衰竭的治疗得到彻底的革命,但仍有部分问题需要澄清.已发表的各个研究结果设计不尽相同,致使对该项治疗的效果较难得出一致的结论.但这些研究都强调干细胞治疗在未来心血管疾病的治疗中可能会发挥较大的作用.干细胞治疗与药学、外科及介入治疗的结合会显著改善冠心病患者的预后.     

肺炎支原体感染与婴幼儿哮喘

呼吸道感染是耍幼儿哮喘发病的重要因素,肺炎支原体(mycoplasma pneumoniae,Mp)与婴幼儿哮喘的关系是近年研究的热点之一.Mp作为社区获得性常见病原体之一在婴幼儿感染率有增高趋势.Mp感染导致婴幼儿哮喘初次和反复发作可能的机制为:Mp感染可直接损伤呼吸道上皮细胞、影响细胞及体液免疫、粘液分泌和呼吸道上皮内神经调节机制紊乱;反复发作与呼吸道对刺激因子呈现高反应性、呼吸道慢性炎症及婴幼儿特应性体质有关.大环内酯类药物具有抗炎和免疫调节作用.用于治疗Mp相关喘息性疾病时取得了一定疗效.     

禅悟与空灵之美

禅悟方法一般分为渐悟与顿悟,其目的都是悟得佛性,成就涅槃正果,最终在空灵之美的境界中使个体人生艺术化、审美化。在禅悟过程中,自然而然的态度,自性自渡的途径,明心见性的妙悟,既是重要的法门,也构成中国美学的独特内容。     

成败等因素对小学生游戏中自我价值感的影响

本研究以三、四年级的142名小学生为被试,以自编的"背投沙包"游戏为载体,通过创设竞争与合作的四类小组以及控制成功与失败的结果,探讨其对个体自我价值感的影响。研究发现,个体的自我价值感受到个体成败而非群体成败的影响,其中人际关系起着部分中介作用。尤其是在失败的结果产生后,极端的高能力重视水平能够带来高自我价值感。而竞争与合作的小组安排对自我价值感的影响并不显著。     

Seeing My World in a Million Little Pieces: Narcissism, Self-Construal, and Cognitive–Perceptual Style

ABSTRACT In 4 studies we examine the association between narcissism, self-construal, and cognitive–perceptual style, hypothesizing that high self-focus in combination with low other-focus (i.e., social atomization) is related to an analytic cognitive–perceptual style. Participants completed the Narcissistic Personality Inventory, the Self-Construal Scale, and measures of cognitive–perceptual style such as the Analysis-Holism Scale, the Embedded Figures Test, a visual illusion test, and a measure of the representativeness heuristic. We found evidence for a decontextualized cognitive–perceptual style in socially atomized participants, which included those high in narcissism and also those who had a combination of high independent and low interdependent self-construal. A meta-analytic integration of our findings found that narcissism was positively related to independent and negatively related to interdependent self-construal, and mediation analyses found some evidence that the relationship between self-construal and cognitive–perceptual style is partially mediated by narcissism.     

Alone and without purpose: Life loses meaning following social exclusion

Four studies (N = 643) supported the hypothesis that social exclusion would reduce the global perception of life as meaningful. Social exclusion was manipulated experimentally by having a confederate refuse to meet participants after seeing their videotaped introduction (Study 1) and by ostracizing participants in a computerized ball-tossing game (Study 2). Compared to control condition and acceptance conditions, social exclusion led to perceiving life as less meaningful. Exclusion was also operationalized as self-reported loneliness, which was a better predictor of low meaning than other potent variables (Study 3). Study 4 found support for Baumeister’s model of meaning (1991), by demonstrating that the effect of exclusion on meaning was mediated by purpose, value, and positive self-worth.     

The moderating and mediating role of group identification in observers' reactions to intragroup disrespect

The current research examines observer reactions to disrespectful treatment of another ingroup member by an ingroup authority. In an empirical study which identifies both the moderating and mediating role of group identification in tandem, specifically with regard to the observed intragroup disrespect, relational motives appeared to underlie subsequent observer evaluations of the group as a whole. Respondents' pre‐transgression identification with the group in which the injustice occurred moderated reactions to intragroup disrespect; only when group members identified strongly with the group did they react to more severe disrespect with worse evaluations. Group identification also mediated the impact of disrespect on subsequent reactions toward the group. Additionally, the relationship between observed disrespect severity and post‐transgression identification with the group was further mediated by perceptions of membership value in the group. Copyright © 2007 John Wiley & Sons, Ltd.     

Perception2

The article is an overview of some central philosophical problems associated with perception. It discusses what distinguishes perception from other sensory capacities and from conception. It discusses anti‐individualism, a view according to which the nature of a perceptual state is dependent not just causally but for its identity or ‘essence’ on relations to a normal environment in which systems containing that state were formed. It discusses different views about epistemic warrant. By emphasising the deep ways in which human and animal perceptual systems, especially visual systems, are similar, it criticises a dominant view of the last century, in both philosophy and large parts of psychology, according to which a range of sophisticated supplementary abilities have to be learned before a child can perceive objective features of the physical world.     

说服效应的理论模型、影响因素与应对策略

说服效应是指面临说服性信息时, 个体态度发生转变并影响其决策行为的一种现象, 该现象普遍存在于政治选举、生活消费及商业广告等领域, 具有重要的应用价值。说服效应的两个主要理论模型包括双加工模型和自我功效理论。信息源的可信度、情绪、信息框架、社会网络、事件卷入度等是影响说服效应的主要因素。说服效应的应对策略包括公开承诺和自我控制。未来的研究应该从说服效应的产生根源、特征成分及应用领域等方面进行深入地探讨。     

失用性失写的脑机制

失用性失写是指人们知道该如何书写, 但实际上却不会书写或错误书写的一种现象。失用性失写涉及的神经网络包括皮层与皮层连接、皮层与皮质下连接。其中前者包括额-顶叶相关脑区的连接、顶-枕叶相关脑区的连接以及额-顶-枕相关脑区的连接, 这些神经网络分别负责操作空间表征图像、回忆以及检索字母的形状等; 后者包括小脑与额-顶叶的连接、左丘脑-大脑皮质的连接以及纹状体-内囊-左额顶叶的连接等, 它们分别与图像输出程序、书写运动过程、操作指令的执行过程以及字素形成过程等有关。今后的研究应该集中在完善失用性失写的研究范式、深入探讨失用性失写的心理机制以及推动其康复工作的开展等方面。