A case of thalamic aphasia with postmortem verification

This study discusses a case of aphasia after dominant thalamic lesion, a hemorrhagic infarction. Unlike other such cases, both repeated standardized assessment and postmortem verification were available. The patient was assessed at 3 weeks and again at 9 weeks postonset. The aphasia demonstrated the syndrome common to dominant thalamic hemorrhage: fluent but paraphasic output sometimes deteriorating to jargon, comprehension less impaired than this type of output usually indicates, and the least impairment in repetition. As sometimes reported in previous cases, semantic paraphasias were more common than phonemic paraphasias. The lesion was located in the dorsal aspect of the lateral nucleus, but it extended into the pulvinar, including the anterior superior lateral aspect which has been implicated in language by previous studies. Thus, data from this case are consistent with an involvement of the dominant pulvinar in language and suggest that this role involves the semantic aspects of language.     

Food-search behavior and its relation to the central excitatory state in the genetic analysis of the blow fly Phormia regina

Dethier (1957) described an aspect of food-search behavior in Phormia regina as the blow fly dance. A hungry fly walks in relatively straight lines with its proboscis retracted until it encounters food (sucrose). After ingesting even a small amount of sucrose, the fly begins making frequent, tight turns, flexes its front tarsi to bring more chemosensory hairs into contact with the substrate and repeatedly extends and retracts its proboscis. Like the central excitatory state (CES), which causes an increase in proboscis extensions to water when a fly is stimulated with sucrose, the dance lasts longer in hungrier flies or with higher sucrose concentrations. It was considered that dance behavior might be an ethologically relevant manifestation of CES. In order to test this hypothesis, dance duration in lines selected for high- and low-CES levels was measured. As predicted, flies from the high-CES line danced longer than those from the low-CES line, and the CES-dance correlation in individual flies was high. This phenotypic correlation disappeared in the F2 generation of a cross between the high- and low-CES lines, a result indicating that the observed variations in CES and dance duration were not caused by the same set of genes. Further characterization of the underlying genetic system showed that several linked autosomal genes with digenic epistatic interactions and a complex pattern of maternal inheritance were responsible for the difference in dance durations between the high- and low-CES lines.     

Effects of Suntan on Judgements of Healthiness and Attractiveness by Adolescents1

The present study sought to explore the relationship between level of suntan and perceptions of healthiness and attractiveness. The sample consisted of 191 students with a mean age of 14 years from five Victorian secondary schools. Subjects were presented with a series of slide pairs of models and asked to indicate the healthier and more attractive stimulus model in each pair. Systematically varied independent variables were: tan level (4 levels: no tan, light, medium, and dark tan), attire (swimwear and casual), sex of model, and sex of subject. Judgements of healthiness and attractiveness were moderately related to each other, the same judgement being made two thirds of the time. Results indicate that a medium tan is perceived as healthiest and most attractive, and “no tan” is perceived as both least healthy and attractive. Generally, darker tans were judged relatively more healthy and more attractive for judgements of male models, judgements of models who wore swimwear, and overall by subjects who desired a dark tan. Sex of subject affected judgements of attractiveness but not healthiness, with male subjects seeing darker tans as more attractive than female subjects. These findings confirm that perception of both healthiness and attractiveness are affected by level of suntan. That suntans have these attributes is a barrier to skin cancer control campaigns designed to encourage reduced exposure to the sun, although the lower level of preferences for the darkest tan level is reassuring.     

The Structure of Anxiety and Depression in a Normative Sample of Younger and Older Australian Adolescents

It has been reported that depression and anxiety have overlapping symptoms and are conceptually interrelated. One of the most prominent theoretical developments that explain this association is Clark and Watson’s tripartite model (Journal of Abnormal Psychology, 100:316–336, 1991) that posits these two disorders and negative emotions share a latent component of negative affect (NA). The current study had two aims, (a) to compare a tripartite factor structure against competing models by Confirmatory Factor Analysis (CFA) of the Depression Anxiety and Stress Scales (DASS-21) (Lovibond and Lovibond 1995), and (b) explore the psychometric properties of the DASS-21. The DASS-21 was completed by a representative sample of 4039 young Australians, aged 12–18 years, as part of the South Australian Youth Mental Health Survey (SAYMHS), South Australia, Australia. The best fitting model for the data consisted of anhedonic depression, physiological hyperarousal, and general NA. The psychometric properties of the DASS-21 were excellent with a stable and interpretable factor structure and good internal consistency. The results of the current study suggest that the theoretical tripartite structure of depression and anxiety is robust and applicable among Australian youth. The diagnostic, clinical and theoretical implications of these findings are discussed.     

Effects of Message Framing on Breast-Cancer-Related Beliefs and Behaviors: The Role of Mediating Factors

The effects of gain-loss message framing on breast-cancer-related cognitions and behaviors were assessed among 539 women aged 30 to 70 years. The design involved a prebrochure telephone interview, followed by a brochure mailout, and a postbrochure telephone interview. The brochures contained information about breast cancer and the risk of family history. Recommended behaviors were framed to emphasize gains, losses, or were neutral; and statistical risk information was presented either positively or negatively. Measures included demographics, family history, breast self-examination (BSE) performance, BSE intention, self-efficacy in performing BSE, perceived early detection risk of breast cancer, perceived susceptibility to breast cancer, and anxiety about breast cancer. A loss-framed message led to greater positive change in BSE behavior. Interactions between framing effects and variables of issue involvement, perceived early detection risk, and self-efficacy indicated effects on behavior, but not beliefs.     

Duns Scotus on the metaphysics of virtue and conformity to right reason

For Duns Scotus, facts about moral psychology are ultimately reducible to facts about ontology. The created agent has a soul which includes as formal “parts” the intellect and will; the intellect and will, of course, are the seat of qualities (e.g. thoughts and volitions, respectively) and habits (e.g. virtues) that are related to one another in various ways. One of these ways is the conformity relation. From a metaphysical base of categorical being – whether Substance, Quality/Habit, or Relation – Scotus constructs an ethical theory which complements, though in some interesting ways departs from, the Aristotelian tradition of which he is a part. In this essay, our aim is twofold: first, to reconstruct the ontological status of virtue within Scotus's overall metaphysical framework. Second, we attend to the ways in which this metaphysic of virtue places constraints on how one is to understand the conformity relation that, according to Scotus, must exist between an agent's will and right reason whenever a morally good action results.     

Demarcating depression

How to draw the line between depression‐as‐disorder and non‐pathological depressive symptoms continues to be a contested issue in psychiatry. Relatively few philosophers have waded into this debate, but the tools of philosophical analysis are quite relevant to it. In this paper, I defend a particular answer to this question, the Contextual approach. On this view, depression is a disorder if and only if it is a disproportionate response to a justifying cause or else is unconnected to any justifying cause. I present four objections to this approach and then defend it from them. Along the way, I explain why it matters whether we get this question right.     

Residual outcome expectations and relapse in ex-smokers.

From a social cognitive theoretical point of view, strong positive outcome expectations of smoking are a cause of relapse in smoking cessation, working in concert with self-efficacy. This study investigated whether and to what extent this could be verified in a sample of ex-smokers. Some (N = 324) ex-smokers were followed for 7 months. At Time 1 (T1) and Time 2 (T2), participants filled in a self-report questionnaire assessing residual outcome expectations (ROEs), self-efficacy, craving for tobacco, and smoking behavior, which was sent and returned by mail. First, prospective analyses showed that ROEs assessed at T1 predicted relapse reported at T2 over and above self-efficacy. Second, the influence of ROEs (and self-efficacy) on relapse was mediated by craving experience. Third, the hypothesized interactions between ROEs and self-efficacy were significant and meaningful.