Dissociation of reward and effort sensitivity in methcathinone‐induced Parkinsonism

Methcathinone‐induced Parkinsonism is a recently described extrapyramidal syndrome characterized by globus pallidus and substantia nigra lesions, which provides a unique model of basal ganglia dysfunction. We assessed motivated behaviour in this condition using a novel cost‐benefit decision‐making task, in which participants decided whether it was worth investing effort for reward. Patients showed a dissociation between reward and effort sensitivity, such that pallidonigral complex dysfunction caused them to become less sensitive to rewards, while normal sensitivity to effort costs was maintained.     

'Assaults upon the Self': Control and Surveillance in a Theological College

Training in a residential setting is a compulsory aspect of the professional preparation of those offering themselves for ordained ministry within the various denominations of Anglican Communion in the UK. This mode of preparation is seen as essential to an inculcation of the 'attitudes and habits' required of future occupational roles and status. The mode as well as the content of training can, therefore, be viewed as powerful facilitators of occupational socialisation and identity. The paper explores how residential training in one setting, through the timetable and 'gaze' of staff and other students, acts to regulate the body in preparation for the transition to an ordained status. The paper further outlines some of the means by which students conform to and contest this 'curriculum of the body'.     

A funny thing happened on the way to articulation: N400 attenuation despite behavioral interference in picture naming

We measured Event-Related Potentials (ERPs) and naming times to picture targets preceded by masked words (stimulus onset asynchrony: 80 ms) that shared one of three different types of relationship with the names of the pictures: (1) Identity related, in which the prime was the name of the picture ("socks" - ), (2) Phonemic Onset related, in which the initial segment of the prime was the same as the name of the picture ("log" - ), and (3) Semantically related in which the prime was a co-category exemplar and associated with the name of the picture ("cake" - ). Each type of related picture target was contrasted with an Unrelated picture target, resulting in a 3×2 design that crossed Relationship Type between the word and the target picture (Identity, Phonemic Onset and Semantic) with Relatedness (Related and Unrelated). Modulation of the N400 component to related (versus unrelated) pictures was taken to reflect semantic processing at the interface between the picture's conceptual features and its lemma, while naming times reflected the end product of all stages of processing. Both attenuation of the N400 and shorter naming times were observed to pictures preceded by Identity related (versus Unrelated) words. No ERP effects within 600 ms, but shorter naming times, were observed to pictures preceded by Phonemic Onset related (versus Unrelated) words. An attenuated N400 (electrophysiological semantic priming) but longer naming times (behavioral semantic interference) were observed to pictures preceded by Semantically related (versus Unrelated) words. These dissociations between ERP modulation and naming times suggest that (a) phonemic onset priming occurred late, during encoding of the articulatory response, and (b) semantic behavioral interference was not driven by competition at the lemma level of representation, but rather occurred at a later stage of production.     

Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

A key criticism of the main diagnostic tool in psychiatry, the Diagnostic and Statistical Manual of Mental Health Disorders (DSM-IV), is that it lacks a biological footing. In this article, we argue for a biological approach to psychiatry based on 'neurocognitive endophenotypes', whereby changes in behavioural or cognitive processes are associated with discrete deficits in defined neural systems. We focus on the constructs of impulsivity and compulsivity as key examples of the approach and discuss their possible cross-diagnostic significance, applying them to co-morbidities and commonalities across a range of disorders (attention-deficit/hyperactivity disorder, substance dependence, obsessive-compulsive disorder and eating disorders). We argue that this approach has important implications for the future classification of psychiatric disorders, genetics and therapeutics.     

Conceptualizing Nonsuicidal Self‐Injury as a Process Addiction: Review of Research and Implications for Counselor Training and Practice

Nonsuicidal self‐injury (NSSI) may be characterized as a process addiction for some individuals who self‐injure. The authors review findings on the addictive features of NSSI, including compulsivity, loss of control, continued use despite negative consequences, and tolerance.     

Toward a Pragmatic Psychology

In this article I want to expand on the pragmatism that runs through Being Human: Human Being in order to think about what a pragmatic psychology might look like. Baert (2005) argued that a pragmatist science has to begin with an acknowledgment of the different interests that might be behind inquiry. The aims of inquiry are linked to useful and appropriate methods. I argue that in personality and social psychology the focus should primarily be on achieving hermeneutic understanding, rather than on finding causal explanation.     

Research digest: post-traumatic stress disorder

The onset of weaning is often described as an important early milestone, but it creates considerable emotional turbulence in the motherinfant relationship. The interruption of the breast-feeding relationship, whether gradual or sudden, creates a very special kind of agony for both the mother and baby, especially when a good trusting relationship with the breast has been found. This paper explores some of the hurts and sacrifices made on both sides during weaning, and looks at some of the subtle reactions to mutual feelings of rejection at this time. It also describes some of the difficulties that arise when the work of weaning is compromised by certain anxieties in the feeding relationship. Extracts from several psychoanalytical infant observations are used both to illustrate and to discuss these themes.     

Inhibition and the right inferior frontal cortex

It is controversial whether different cognitive functions can be mapped to discrete regions of the prefrontal cortex (PFC). The localisationist tradition has associated one cognitive function - inhibition - by turns with dorsolateral prefrontal cortex (DLPFC), inferior frontal cortex (IFC), or orbital frontal cortex (OFC). Inhibition is postulated to be a mechanism by which PFC exerts its effects on subcortical and posterior-cortical regions to implement executive control. We review evidence concerning inhibition of responses and task-sets. Whereas neuroimaging implicates diverse PFC foci, advances in human lesion-mapping support the functional localization of such inhibition to right IFC alone. Future research should investigate the generality of this proposed inhibitory function to other task domains, and its interaction within a wider network.