Awareness and Attitudes Regarding Prenatal Testing among Texas Women of Childbearing Age

Despite increased visibility and availability of prenatal testing procedures, very little is known about the attitudes among the populace toward these procedures. Using a computer assisted telephone interview of pregnant and non-pregnant women of childbearing age we analyze awareness and attitudes regarding prenatal tests among a diverse group of women of childbearing age in Texas. We also examine maternal characteristics associated with awareness and the willingness to undergo these procedures. While 89% were aware that such tests are available, younger, black and less educated women were less likely to know about prenatal tests for birth defects. Seventy-two percent of respondents said they would want their baby tested while Hispanic and black women were significantly more likely to express an interest than non-Hispanic whites. This study demonstrates the variability of knowledge and beliefs and confirms the importance of taking time to understand an individual’s personal beliefs, knowledge and attitudes about prenatal diagnosis.     

On trekking to operant frontiers

Only recently have psychologists begun to explore systematically the unmapped territory of validating numerous, detailed operant principles in nonclinical human populations. Several concerns question the usefulness of simplistic leverpressing tasks superficially patterned on nonhuman laboratory studies. A realistic uniform laboratory context for responding would help address some of them. Research conducted by my colleagues and me using the Star Trek computer game is proffered as an exemplar.     

The role of the frontal lobes in the regulation of cognitive development.

Between the ages of 1.5 and 5 years, and again between the ages of 5 and 10 years, a sequence of changes takes place in children's behavior which indicates a fundamental reorganization of their attentional, executive, and self-reflexive processes. In the present article, these changes are summarized, and evidence is adduced to support the claims (1) that these changes are frontally mediated and (2) that the underlying mechanism that generates them is similar to the one that generates the changes in EEG coherence during the same time period. The psychological model that has been hypothesized to explain the cycles of cognitive development (Case, 1992) is then compared to the physiological model that has been proposed to explain cycles of EEG development (Thatcher, 1992). It is shown that the two models are complementary, both in the underlying developmental sequence that they postulate and in the recursive dynamic they propose for producing movement through this sequence. A number of implications and predictions are derived, which follow from the proposition that the two sets of changes are different manifestations of a common underlying process.     

The role of binaural and fundamental frequency difference cues in the identification of concurrently presented vowels

The relative importance of voice pitch and interaural difference cues in facilitating the recognition of both of two concurrently presented synthetic vowels was measured. The interaural difference cues used were an interaural time difference (400 μsec ITD), two magnitudes of interaural level difference (15 dB and infinite ILD), and a combination of ITD and ILD (400 μsec plus 15 dB). The results are analysed separately for those cases where both vowels are identical and those where they are different. When the two vowels are different, a voice pitch difference of one semitone is found to improve the percentage of correct reports of both vowels by 35.8% on average. However, the use of interaural difference cues results in an improvement of 11.5% on average when there is a voice pitch difference of one semitone, but only a non-significant 0.1% when there is no voice pitch difference. When the two vowels are identical, imposition of either a voice pitch difference or binaural difference reduces performance, in a subtractive manner. It is argued that the smaller size of the interaural difference effect is not due to a “ceiling effect” but is characteristic of the relative importance of the two kinds of cues in this type of experiment. The possibility that the improvement due to interaural difference cues may in fact be due to monaural processing is discussed. A control experiment is reported for the ITD condition, which suggests binaural processing does occur for this condition. However, it is not certain whether the improvement in the ILD condition is due to binaural processing or use of the improvement in signal-to-noise ratio for a single vowel at each ear.     

A funny thing happened on the way to articulation: N400 attenuation despite behavioral interference in picture naming

We measured Event-Related Potentials (ERPs) and naming times to picture targets preceded by masked words (stimulus onset asynchrony: 80 ms) that shared one of three different types of relationship with the names of the pictures: (1) Identity related, in which the prime was the name of the picture ("socks" - ), (2) Phonemic Onset related, in which the initial segment of the prime was the same as the name of the picture ("log" - ), and (3) Semantically related in which the prime was a co-category exemplar and associated with the name of the picture ("cake" - ). Each type of related picture target was contrasted with an Unrelated picture target, resulting in a 3×2 design that crossed Relationship Type between the word and the target picture (Identity, Phonemic Onset and Semantic) with Relatedness (Related and Unrelated). Modulation of the N400 component to related (versus unrelated) pictures was taken to reflect semantic processing at the interface between the picture's conceptual features and its lemma, while naming times reflected the end product of all stages of processing. Both attenuation of the N400 and shorter naming times were observed to pictures preceded by Identity related (versus Unrelated) words. No ERP effects within 600 ms, but shorter naming times, were observed to pictures preceded by Phonemic Onset related (versus Unrelated) words. An attenuated N400 (electrophysiological semantic priming) but longer naming times (behavioral semantic interference) were observed to pictures preceded by Semantically related (versus Unrelated) words. These dissociations between ERP modulation and naming times suggest that (a) phonemic onset priming occurred late, during encoding of the articulatory response, and (b) semantic behavioral interference was not driven by competition at the lemma level of representation, but rather occurred at a later stage of production.     

Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

A key criticism of the main diagnostic tool in psychiatry, the Diagnostic and Statistical Manual of Mental Health Disorders (DSM-IV), is that it lacks a biological footing. In this article, we argue for a biological approach to psychiatry based on 'neurocognitive endophenotypes', whereby changes in behavioural or cognitive processes are associated with discrete deficits in defined neural systems. We focus on the constructs of impulsivity and compulsivity as key examples of the approach and discuss their possible cross-diagnostic significance, applying them to co-morbidities and commonalities across a range of disorders (attention-deficit/hyperactivity disorder, substance dependence, obsessive-compulsive disorder and eating disorders). We argue that this approach has important implications for the future classification of psychiatric disorders, genetics and therapeutics.     

Inhibition and the right inferior frontal cortex

It is controversial whether different cognitive functions can be mapped to discrete regions of the prefrontal cortex (PFC). The localisationist tradition has associated one cognitive function - inhibition - by turns with dorsolateral prefrontal cortex (DLPFC), inferior frontal cortex (IFC), or orbital frontal cortex (OFC). Inhibition is postulated to be a mechanism by which PFC exerts its effects on subcortical and posterior-cortical regions to implement executive control. We review evidence concerning inhibition of responses and task-sets. Whereas neuroimaging implicates diverse PFC foci, advances in human lesion-mapping support the functional localization of such inhibition to right IFC alone. Future research should investigate the generality of this proposed inhibitory function to other task domains, and its interaction within a wider network.     

Conceptualizing Nonsuicidal Self‐Injury as a Process Addiction: Review of Research and Implications for Counselor Training and Practice

Nonsuicidal self‐injury (NSSI) may be characterized as a process addiction for some individuals who self‐injure. The authors review findings on the addictive features of NSSI, including compulsivity, loss of control, continued use despite negative consequences, and tolerance.