Neural correlates of lexicon and grammar: evidence from the production, reading, and judgment of inflection in aphasia

Are the linguistic forms that are memorized in the mental lexicon and those that are specified by the rules of grammar subserved by distinct neurocognitive systems or by a single computational system with relatively broad anatomic distribution? On a dual-system view, the productive -ed-suffixation of English regular past tense forms (e.g., look-looked) depends upon the mental grammar, whereas irregular forms (e.g., dig-dug) are retrieved from lexical memory. On a single-mechanism view, the computation of both past tense types depends on associative memory. Neurological double dissociations between regulars and irregulars strengthen the dual-system view. The computation of real and novel, regular and irregular past tense forms was investigated in 20 aphasic subjects. Aphasics with non-fluent agrammatic speech and left frontal lesions were consistently more impaired at the production, reading, and judgment of regular than irregular past tenses. Aphasics with fluent speech and word-finding difficulties, and with left temporal/temporo-parietal lesions, showed the opposite pattern. These patterns held even when measures of frequency, phonological complexity, articulatory difficulty, and other factors were held constant. The data support the view that the memorized words of the mental lexicon are subserved by a brain system involving left temporal/temporo-parietal structures, whereas aspects of the mental grammar, in particular the computation of regular morphological forms, are subserved by a distinct system involving left frontal structures.     

Four studies on how past and current suicidality relate even when "everything but the kitchen sink" is covaried

T. E. Joiner's (2004, in press) theory of suicidal behavior suggests that past suicidal behavior plays an important role in future suicidality. However, the mechanism by which this risk is transferred and the causal implications have not been well studied. The current study provides evaluation of the nature and limits of this relationship across 4 populations, with varying degrees of suicidal behavior. Across settings, age groups, and impairment levels, the association between past suicidal behavior and current suicidal symptoms held, even when controlling for strong covariates like hopelessness and symptoms of various Axis I and II syndromes. Results provide additional support for the importance of past suicidality as a substantive risk factor for later suicidal behavior.     

Income inequality and risk of suicide in New York City neighborhoods: a multilevel case-control study

Evidence on the relationship between income inequality and suicide is inconsistent. Data from the New York City Office of the Chief Medical Examiner for all fatal injuries was collected to conduct a multilevel case-control study. In multilevel models, suicide decedents (n=374) were more likely than accident controls (n=453) to reside in neighborhoods with greater income inequality even after controlling for individual characteristics; this relation was modified by age with an effect overall and among decedents aged 15-34 but not among decedents 35-64. These data suggest that income inequality may contribute to the risk of suicide in younger adults.     

The relations of problem behavior status to children's negative emotionality, effortful control, and impulsivity: concurrent relations and prediction of change

The relations of children's internalizing and externalizing problem behaviors to their concurrent regulation, impulsivity (reactive undercontrol), anger, sadness, and fearfulness and these aspects of functioning 2 years prior were examined. Parents and teachers completed measures of children's (N = 185; ages 6 through 9 years) adjustment, negative emotionality, regulation, and behavior control; behavioral measures of regulation also were obtained. In general, both internalizing and externalizing problems were associated with negative emotionality. Externalizers were low in effortful regulation and high in impulsivity, whereas internalizers, compared with nondisordered children, were low in impulsivity but not effortful control. Moreover, indices of negative emotionality, regulation, and impulsivity with the level of the same variables 2 years before controlled predicted stability versus change in problem behavior status.     

Show your pride: evidence for a discrete emotion expression

Abstract— Three experiments provide converging evidence that pride has a distinct, recognizable expression. Experiment 1 showed that judges can agree in identifying a posed expression as showing pride and can reliably distinguish pride expressions from expressions of related emotions such as happiness. Experiment 2 showed that judges can identify the pride expression when the task uses an open-ended response format that does not cue them with the label "pride." Experiment 3 showed that the pride expression includes a small smile, with head tilted slightly back, visibly expanded posture, and arms raised above the head or hands on hips. Overall, these findings challenge the assumption that all positive emotions share the same expression, and suggest that pride may be added to the pantheon of basic emotions generally viewed as evolved responses.     

The Ohio study in light of national data and clinical experience

The Siminoff, Burant, and Youngner study in Ohio is strikingly consistent with data from a national study. Both suggest that there might be significant public acceptance of future policies that violate the dead donor rule, or that further extend the boundary between life and death to include brain-damaged patients short of "brain death." Experience with donation suggests that many individuals would donate their loved ones' organs when they have concluded that the brain injury is not survivable, even if all the criteria for "brain death" are not met. It would be very helpful to have research on those who have gone through the real-life clinical situation. Based on the findings of this study and the increasing demand for organs, it may be appropriate for public policy to allow for ways to increase organ procurement from individuals who are not fully "brain dead" beyond the current method of procurement after cardiac death, but any change in this area should go slowly and with significant public input.     

Variations in Anxiety and Depression as a Function of ADHD Subtypes Defined by DSM-IV: Do Subtype Differences Exist or Not?

Concerns have been raised about the ability of diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD) to distinguish subtypes that are clearly distinct from each other with regard to clinical correlates. One area of concern is that research regarding differences in anxiety and depression as a function of ADHD subtype has produced discrepant findings. This study was designed to systematically evaluate whether the ADHD subtypes differ with regard to level of internalizing symptoms. From a large pool of children referred to an ADHD center based in a pediatric hospital, children were differentiated into three groups: ADHD, Combined Type (ADHD/COM); ADHD, Inattentive Type (ADHD/I); and a non-ADHD, comparison group (COMP). Parent- and child-report measures using both dimensional and categorical methods were used to assess internalizing symptoms. The results indicated that children with ADHD/COM and ADHD/I had similar levels of anxiety and depression. Subtype differences related to parent-reported depression were accounted for by group differences in level of externalizing problems. The results were discussed with regard to their implications for refining the criteria used to differentiate children with ADHD into subtypes.     

A woman's struggle in academic psychology (1936-2001)

Tracy S. Kendler's strong desire to get a college education had to overcome economic hardships of the Great Depression and a mother's conviction that finding a suitable husband was more important. Solomon Asch at Brooklyn College, by scholarly example, encouraged her to seek a career in psychology. At the University of Iowa she studied with both Kurt Lewin and Kenneth Spence and finally opted to conduct a research program, ultimately on cognitive development, within a neobehavioristic methodological orientation. Being married to academic psychologist Howard H. Kendler, and a mother of 2 sons, created problems in fashioning an independent academic career, but persistence and research productivity, sometimes a result of collaborative efforts with her husband, finally led to a distinguished career.     

Inhibition of return to color: A replication and nonextension of Law, Pratt, and Abrams (1995)

We presented subjects with an unpredictive cue that was followed after a 150- to 900-msec interstimulus interval (ISI) by a detection target. Cue and target were blue or red squares that appeared at fixation and in an otherwise uniform black field. In a filler condition, a task-irrelevant filler stimulus (magenta square) was presented during the ISI; in a no-filler condition, no stimulus appeared during the ISI. Using only a 900-msec ISI, Law, Pratt, and Abrams (1995) reported slower reaction times (RTs) when cue and target were the same color, but only when the task-irrelevant filler was presented during the ISI. They argued that attention is first drawn to the cue color and that inhibition of return (IOR; see Posner & Cohen, 1984) is established when attention is drawn away from that cue color representation by the task-irrelevant filler. Critical to their view is the assumption that IOR occurs only after attention is drawn away from the cue color by the filler. Assuming a time course for the withdrawal of attention from the cue color representation, Law et al. ’s view predicts growth of the inhibitory effect as a function of ISI in the filler condition as well as facilitation at early ISIs in the no-filler condition (because there is no filler to withdraw attention from the cue color). Contrary to these predictions, we found that the inhibitory effect observed by Law et al. at the 900-msec ISI was present at—and did not vary in magnitude across—the range of ISIs tested. And there was never facilitation in the no-filler condition. These results challenge Law et al. ’s inference that IOR for foveally presented colors was operating in their paradigm.